Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,643 recruiting studies in this area right now.
By phase
- Not applicable4,313
- Phase 2851
- Phase 1471
- Phase 3424
- Phase 1/Phase 2309
- Phase 4209
- Phase 2/Phase 366
Top conditions
- Lung Cancer425
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD142
- Breast Cancer111
- COVID-19107
- Pulmonary Hypertension101
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Interstitial Lung Disease79
- Pneumonia79
- Cystic Fibrosis78
- Chronic Obstructive Pulmonary Disease (COPD)73
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca64
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona155
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas91
- Pennsylvania82
- Illinois72
Recruiting studies6,643 total
- NCT06066723Recruiting
MRI study for healthy children and mild cystic fibrosis
This study uses a special MRI that can show inflammation in the lungs. It looks at healthy children and children with mild cystic fibrosis to test if the scan can detect early changes. If you join, you will breathe in a special gas during the MRI.
Chapel Hill, North CarolinaAges 6–17 - NCT06453876RecruitingPhase 3
Comparing clot removal, low-dose clot dissolver, and heparin for high-risk lung clot
This trial compares three treatments for an intermediate-high risk pulmonary embolism: a minimally invasive clot removal procedure (embolectomy), a low-dose clot-dissolving medication, or standard blood thinning (heparin). The goal is to see which approach works best to prevent worsening while reducing bleeding risks.
CopenhagenAges 18 years+ - NCT07681973Recruiting
Smell training for loss of smell in sinus patients
This study tests whether smell training can improve your sense of smell and affect your immune system. It is for people with chronic sinus inflammation and nasal polyps who have lost their sense of smell.
Cleveland, OhioAges 18 years+ - NCT07482917Recruiting
Streamlining the diagnosis of interstitial lung disease
This study is testing a new way to speed up the diagnosis of interstitial lung disease (a group of lung scarring conditions). If you have symptoms or scan findings that suggest ILD but haven't been fully diagnosed yet, this trial may help you get a faster, clearer answer.
Granollers, BarcelonaAges 18 years+ - NCT04645602RecruitingPhase 2
Study of pembrolizumab and lenvatinib for lung papillomas
This early-phase trial tests how well pembrolizumab plus lenvatinib can treat respiratory papillomas that have spread to the lungs. It may help people whose lung disease is caused by human papillomavirus (HPV).
New Haven, ConnecticutAges 18 years+ - NCT06979323RecruitingPhase 3
Depemokimab study for asthma with imaging and bronchoscopy
This study tests depemokimab, an injectable biologic, to see how it works in the lungs of people with severe asthma. You would get the drug and have special imaging and a bronchoscopy (a tube with a camera placed into your airways to take tiny tissue samples) so doctors can understand how the medicine reduces inflammation.
Brooksville, FloridaAges 18 years+ - NCT06159127Recruiting
SMART@Home: A smartphone program for teens with chronic conditions
This trial is testing a new program called SMART@Home that helps teens manage their long-term health conditions using a smartphone app. It aims to see if this approach is practical and helpful for teens with conditions like asthma.
Cincinnati, OhioAges 12–18 - NCT07681583Recruiting
Fungal pneumonia risk score study
This study is developing a tool to better predict fungal pneumonia in people who come to the emergency department or hospital with pneumonia. By analyzing samples from your lungs and other data, researchers hope to improve diagnosis and treatment decisions.
FlorenceAges 18–90 - NCT07223255Recruiting
Mediterranean diet study for children with cystic fibrosis
This study tests whether a Mediterranean-style diet can improve gastrointestinal health in children with cystic fibrosis. It requires families to follow the diet for 6 months and attend regular clinic visits.
Lebanon, New HampshireAges 3–18 - NCT07330778RecruitingPhase 1
Study of CDX-622 for mild to moderate asthma
This trial is testing an investigational drug called CDX-622 for people with mild to moderate asthma. The study aims to see if it can help control asthma symptoms and improve lung function.
San Francisco, CaliforniaAges 18 years+ - NCT06057714Recruiting
MRI study of airway function in cystic fibrosis
This study uses a special MRI technique (19F MRI) to look at how well your lungs are working and where any blockages are. The goal is to understand airway problems in cystic fibrosis better.
Chapel Hill, North CarolinaAges 18–99 - NCT03412877RecruitingPhase 2
Personalized immune-cell therapy for advanced metastatic cancers
This trial tests a personalized cell therapy made from your own immune cells, changed to recognize “neoantigens” on cancer cells. It’s designed for people with metastatic (advanced spread) solid cancers or certain other cancers who have tried standard treatments but cancer is still growing.
Bethesda, MarylandAges 18–72 - NCT07059884Recruiting
Exercise program to help people with cancer stay active
This trial tests a distance-based exercise program designed to help people on chemotherapy maintain their physical function and prevent disability. It is for patients with certain cancers who are working full-time and can participate in moderate physical activity.
Dublin, CaliforniaAges 18 years+ - NCT07312734Recruiting
Testing new ways to find lung germs in CF
This study tests a new method to detect bacteria in the lungs of people with cystic fibrosis (CF) by analyzing mucus samples. It aims to improve how we diagnose and treat lung infections.
La Jolla, CaliforniaAges 16 years+ - NCT07447232Recruiting
Ultrasound vs. standard breathing test for lung disease
This trial compares a new ultrasound breathing test (spirometry) to the standard one. If you have a chronic lung condition like COPD or asthma, it could help see if the new method is as good as the old one.
New Taipei CityAges 18–80 - NCT07254000RecruitingPhase 2
Anakinra dosing study for preterm infants
This trial tests different doses and ways of giving a medicine called anakinra to preterm babies. It aims to find the safest and most effective dose to help reduce inflammation.
Clayton, VictoriaAges 6 months–7 months - NCT07254026Recruiting
Precision health and smart telerehabilitation for sleep apnea
This trial tests a smart home-based program using telerehabilitation to help people with obstructive sleep apnea. It aims to see if personalized health coaching and remote exercise can improve sleep and overall health.
TainanAges 20 years+ - NCT07254338Recruiting
Blood chemicals study in lung scarring and high lung blood pressure
This study looks at special chemicals in the blood (metabolites) from people with both lung scarring and high lung blood pressure. It aims to learn how these chemicals change with or without treatment for the lung blood pressure.
Bron, RhoneAges 18 years+ - NCT07255131Recruiting
Online talk therapy for cystic fibrosis
This study tests an online cognitive behavioral therapy (a type of talk therapy) program designed for people with cystic fibrosis. It aims to help improve mental health and coping skills through 13 video sessions.
AthensAges 18–70 - NCT07255430Recruiting
Airway bacteria study for children with PBB
This study looks at the bacteria in the airways of children with Protracted Bacterial Bronchitis (PBB), a long-lasting cough caused by bacteria. It aims to understand how these bacteria affect the condition, which could lead to better treatments.
EdegemAges Up to 5 years - NCT07255950Recruiting
Comparing lung biopsy methods for suspected lung cancer
This study compares two ways of doing a lung biopsy with a needle guided by ultrasound. It aims to see which method gives better samples for diagnosing lung cancer.
Yogyakarta, Special Region of YogyakartaAges 18 years+ - NCT07257458Recruiting
Lung cancer early detection and monitoring trial
This trial uses special markers in the blood to find lung cancer early and track if it comes back after treatment. It is for people with non-small cell lung cancer who are able to have surgery.
Beijing, Beijing MunicipalityAges 18–85 - NCT07257471Recruiting
Methylation markers in early-stage lung cancer with ablation therapy
This trial tests if a special treatment called co-ablation can help people with early-stage non-small cell lung cancer who cannot or choose not to have surgery. It also looks at certain markers in the blood to better understand the cancer.
Beijing, Beijing MunicipalityAges 18–85 - NCT07258784Recruiting
Studying windpipe tissue to understand non-cancerous narrowing
This study uses a small piece of tissue from your windpipe to look at the genes and cells that cause benign (non-cancerous) tracheal stenosis. It aims to understand why the narrowing happens, which could lead to better treatments.
Baltimore, MarylandAges 18–80
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,643 recruiting pulmonology studies from the U.S. registry right now, out of 10,656 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.