Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,643 recruiting studies in this area right now.
By phase
- Not applicable4,313
- Phase 2851
- Phase 1471
- Phase 3424
- Phase 1/Phase 2309
- Phase 4209
- Phase 2/Phase 366
Top conditions
- Lung Cancer425
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD142
- Breast Cancer111
- COVID-19107
- Pulmonary Hypertension101
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Interstitial Lung Disease79
- Pneumonia79
- Cystic Fibrosis78
- Chronic Obstructive Pulmonary Disease (COPD)73
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca64
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona155
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas91
- Pennsylvania82
- Illinois72
Recruiting studies6,643 total
- NCT07410676RecruitingPhase 1/Phase 2
Donor NK cells with IL-15 and pembrolizumab for advanced solid tumors
This trial tests a new type of cell therapy (natural killer cells) made from a donor, combined with low-dose IL-15 (a protein that helps these cells work) and sometimes with pembrolizumab (Keytruda), for people with advanced solid tumors that have not responded to standard treatments. The goal is to see if this combination can shrink tumors or slow their growth.
Beijing, Beijing MunicipalityAges Any age - NCT07410975RecruitingPhase 2
Immunotherapy and chemo before surgery for lung cancer
This trial tests combining two immunotherapy drugs (anti-CTLA-4 antibody and sintilimab) with chemotherapy before surgery for stage II-III non-small cell lung cancer. The goal is to see if this approach helps shrink tumors and improve outcomes.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07411417Recruiting
Acupressure for pain and lung function after chest surgery
This trial tests if acupressure can help reduce pain and improve lung function after a first-time chest surgery. It may offer a non-drug way to support recovery.
IstanbulAges Any age - NCT07412327Recruiting
Proton therapy for early stage lung cancer
This trial tests a precise form of proton radiation for people with early stage lung cancer who cannot have surgery. It aims to see if this treatment is effective and safe.
Guangzhou, GuangdongAges 18 years+ - NCT07413094RecruitingPhase 2
Testing a new drug for sepsis-related lung injury
This trial tests a new medicine called YD0743 for people who have both sepsis (a serious infection) and ARDS (a severe lung injury from the infection). The goal is to see if the medicine helps improve breathing and survival.
BeijingAges 18–75 - NCT07413978RecruitingPhase 1/Phase 2
Stem cell injection for severe ARDS
This trial tests whether an injection of stem cells from umbilical cords can help people with severe ARDS (a type of lung failure) recover faster. It is for those who have not improved after standard treatment and whose ARDS is caused by an infection (not COVID-19).
Wuhan, HubeiAges 18–80 - NCT07414056Recruiting
Can blood tests predict lung injury in burned children?
This study is testing whether simple blood tests can predict a dangerous lung condition called ARDS in children with severe burns. Researchers will check the child's white blood cell and platelet counts to look for early warning signs that could help doctors treat them faster.
CairoAges 1–12 - NCT07414108Recruiting
Predicting response to breathing support in COPD
This study looks at whether nighttime breathing problems can predict long-term success with a non-invasive breathing machine in people with COPD who have high carbon dioxide levels in their blood. The goal is to help doctors decide who will benefit most from this therapy.
BolognaAges 18 years+ - NCT07414693RecruitingPhase 4
Vitamin C for kids with severe pneumonia
This trial tests if giving vitamin C to children hospitalized with severe pneumonia can help them get better faster and leave the hospital sooner. It may be an option for children who have had pneumonia symptoms for 48 hours or less.
Multan Khurd, Punjab ProvinceAges 2 months–4.9 years - NCT07416994RecruitingPhase 3
Study of YL202 vs. docetaxel for advanced EGFR-mutant lung cancer
This trial tests a new drug, YL202, against a standard chemotherapy (docetaxel) for people with a specific type of advanced non-small cell lung cancer that has an EGFR mutation. The goal is to see if YL202 works better for those whose cancer has progressed after prior treatments.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07418450Recruiting
Comparing two needle methods for lung cancer staging
This trial compares two ways of collecting tissue samples from lymph nodes in the chest during a procedure called EBUS-TBNA. The goal is to see if changing the needle during the procedure gives better results for diagnosing lung cancer.
ViennaAges 18 years+ - NCT07418736RecruitingPhase 2
CM326 for moderate to severe COPD
This trial tests a new medicine called CM326 for people with moderate to severe COPD. It aims to see if the drug can reduce flare-ups and improve lung function.
Beijing, Beijing MunicipalityAges 40–85 - NCT07419230Recruiting
Digital tool to help with allergy shot adherence
This trial tests a digital tool designed to help patients stick to their allergy immunotherapy schedule. If you have allergic rhinitis (with or without asthma) and are starting a new single-allergy treatment, you may be able to join.
Madrid, MadridAges Any age - NCT07419360Recruiting
Draining fluid from lungs in heart failure
This study tests whether draining fluid from around the lungs can help people with heart failure who are in the hospital. It looks at how this procedure affects breathing and recovery.
Albany, New YorkAges 18 years+ - NCT07419464RecruitingPhase 2
Testing 5-FU for head and neck cancer that has returned
This trial tests the drug 5-fluorouracil (5-FU) in people with head and neck cancer that has come back or spread. It aims to see if 5-FU can help when other treatments have stopped working.
St Louis, MissouriAges 18 years+ - NCT07420985RecruitingPhase 2
Ingavirin forte for flu and other viral infections
This trial tests different doses of Ingavirin Forte capsules for treating influenza and other respiratory viruses. It may help people with fever, cough, sore throat, and body aches who have been sick less than 48 hours.
IvanovoAges 18–65 - NCT07423988Recruiting
Sleep changes at high altitude for Pic du Midi staff
This study looks at how sleep quality changes when you work overnight at high altitude (2877m) at the Pic du Midi observatory, compared to sleeping at home. It helps understand the effects of high-altitude work on rest.
Toulouse, OuiAges 18–65 - NCT07424547RecruitingPhase 1
Study of SYS6043 for advanced or metastatic solid tumors
This trial tests a new study drug (SYS6043) for people with advanced or metastatic solid tumors that have not responded to or are not candidates for standard therapies. The drug targets a protein called B7-H3 on cancer cells to help stop tumor growth.
Plantation, FloridaAges 18 years+ - NCT07426016Recruiting
Comparing two ways to give surfactant to premature babies
This study compares two methods—video laryngoscopy and direct laryngoscopy—to give surfactant (a medicine that helps babies' lungs work better) to very premature infants. It aims to find which method is safer and easier for babies born at 28 weeks or earlier who need surfactant within the first 36 hours after birth.
Dallas, TexasAges birth–3 days - NCT07426458RecruitingPhase 4
Breathing and blood flow study for adults with asthma
This study looks at how asthma affects air flow and blood flow in your lungs. You may join if you use daily asthma control medicine and your breathing test shows room for improvement even after using a rescue inhaler.
Miami, FloridaAges 18–75 - NCT07426718Recruiting
Breath test for airway inflammation in lung diseases and healthy people
This study is testing a simple breath test (Inflammacheck device) to see if it can measure airway inflammation in people with various lung conditions, including lung cancer, pneumonia, asthma, and COPD, as well as healthy volunteers. It aims to find better ways to diagnose and monitor respiratory diseases using your breath.
Portsmouth, HampshireAges 18 years+ - NCT07427537Recruiting
Studying nerve damage from chemotherapy in colorectal and lung cancer patients
This study looks for small molecules in the blood that might predict nerve damage caused by certain chemotherapies. If you have colorectal or lung cancer and are starting a specific chemo plan, this trial could help researchers understand why some people get nerve problems and others don't.
Clermont-FerrandAges 18 years+ - NCT07428044RecruitingPhase 2
Trastuzumab Deruxtecan for HER2-mutant lung cancer before surgery
This trial tests a targeted drug, trastuzumab deruxtecan, for people with non-small cell lung cancer that has a specific HER2 gene change. The treatment is given before surgery to shrink the tumor and make it easier to remove.
Ann Arbor, MichiganAges 18 years+ - NCT07430124Recruiting
Two breathing methods during balloon dilation for airway procedure
This study compares two ways of delivering breaths during a balloon dilation procedure to see which works better and is safer for your lungs.
AnkaraAges 18–65
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,643 recruiting pulmonology studies from the U.S. registry right now, out of 10,656 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.