Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2848
- Phase 1470
- Phase 3423
- Phase 1/Phase 2310
- Phase 4207
- Phase 2/Phase 367
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer179
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Riphah International University34
Where studies are running
- California389
- Alabama174
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT06264154Recruiting
Can e-cigarette flavor help you quit smoking?
This study looks at whether the flavor of an e-cigarette can help people who keep smoking switch completely away from regular cigarettes. Participants will use e-cigarettes with different flavors for 6 weeks.
Philadelphia, PennsylvaniaAges 21 years+ - NCT06970990Recruiting
Testing nose pressure to measure breathing effort with oxygen therapy
This trial uses a small tube in your nose to measure how hard you are working to breathe while receiving different types of oxygen therapy. It aims to find out if this nose pressure test can replace a more invasive test, making monitoring easier for you.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07639255Recruiting
Improving lung cancer screening in Kentucky
This study wants to see if a quality improvement program called QUILS can help healthcare workers find lung cancer earlier. It uses surveys, feedback, and interviews to improve how lung cancer screening is done.
Ashland, KentuckyAges 18–100 - NCT06479499Recruiting
Pilates vs aerobic exercise for breathing and anxiety in COPD
This trial compares Pilates exercises with aerobic exercises to see which is better at reducing shortness of breath, improving daily function, and lowering anxiety in people with moderate COPD.
Lahore, Punjab ProvinceAges 45–65 - NCT07027956Recruiting
Smoking and lung function study
This study measures how well your lungs work and how much oxygen is in your blood. It compares smokers and non-smokers to see if smoking affects breathing.
KırşehirAges 18–65 - NCT06998264Recruiting
Immune response to flu in young children
This study looks at how children's immune systems fight the flu in the nose and throat. It aims to understand why some children get very sick and others don't, which could help create better treatments and vaccines.
GenevaAges 2–5 - NCT07501572Enrolling by invitation
Escape room game to prevent tobacco harm for kids
This study tests if a robot-assisted escape room game can help 5th and 6th graders learn about the dangers of tobacco. It may help students make healthier choices.
New Taipei City, Xindian DistrictAges 10–12 - NCT07500987RecruitingPhase 1
Study of Imaging Agent for EGFR-Mutated Lung Cancer
This trial tests a new radioactive imaging agent that helps doctors see EGFR-positive lung cancer cells. It is for people with advanced non-small cell lung cancer that has an EGFR mutation, and who are not currently on a changing cancer treatment.
BeijingAges 18–130 - NCT07498244Recruiting
Collagen fingerprinting to understand lung blood pressure
This study uses a special imaging method to look at collagen (a building block of lung tissue) in people with COPD or pulmonary fibrosis. Researchers want to see if collagen patterns can help doctors better understand and treat high blood pressure in the lungs (pulmonary hypertension).
Graz, StyriaAges 18 years+ - NCT07468968Enrolling by invitation
Balance vs. breathing training for older adults
This study compares two types of training—one focusing on balance exercises and one on breathing muscle exercises—to see which helps older adults more. If you are 60 or older and able to walk on your own, you may be able to join.
IstanbulAges 60 years+ - NCT07517497Recruiting
Lung Vibration Device for Seniors With Hip Fracture and Breathing Problems
This study tests a special vibration device on the chest to help older adults who have both a hip fracture and acute breathing failure recover better. The device uses gentle vibrations to help clear the lungs and improve breathing.
AstanaAges 60–85 - NCT06987461Recruiting
Studying non-invasive ventilation for bronchiectasis
This trial is studying how a mask that helps you breathe (non-invasive ventilation) affects people with bronchiectasis (a condition where airways in the lungs are stretched and scarred). It may help doctors understand if this treatment improves quality of life or slows the disease.
CréteilAges 18 years+ - NCT04537182Recruiting
Surgery versus bronchoscopy for severe emphysema
This study compares two ways to reduce lung “overinflation” in people with severe emphysema: surgery (LVRS) or a bronchoscopy procedure (BLVR). It aims to see which approach works best and is safest for eligible patients.
ViennaAges 30–80 - NCT07482930Recruiting
Nerve stimulation and breathing test study in healthy adults
This study tests if a gentle nerve stimulation device placed on the ear can change how you breathe during a lung function test. It is only for healthy volunteers aged 18–40 who have no heart, lung, nerve, or mental health conditions.
SinopAges 18–40 - NCT07481916Recruiting
Warming up breathing muscles for combat athletes
This study tests whether a special breathing warm-up can help combat athletes perform better. If you are a young, experienced kickboxer or Muay Thai fighter, this trial may be for you.
Samsun, AtakumAges 15–22 - NCT06990308Enrolling by invitation
Comparing breathing tube removal methods
This study compares two ways of removing the breathing tube (extubation) after surgery: one with the tube's cuff inflated and one with it deflated. It aims to see which method may be safer and more comfortable for patients having short, non-airway surgeries.
Marine Corps Base Camp Lejeune, North CarolinaAges 18–50 - NCT07465510Recruiting
Ultrasound vs. other methods for double-lumen tube placement
This study compares three ways to check if a breathing tube is in the right spot during lung surgery: using ultrasound, listening with a stethoscope, or looking with a tiny camera. It aims to find which method works best and is safest.
Izmir, İzmirAges 18–65 - NCT07464730Recruiting
High-flow nasal oxygen after high-risk surgery for frail adults
This trial tests whether using high-flow nasal oxygen after surgery helps frail patients recover better and avoid breathing problems. It includes people having long abdominal, vascular, or chest surgeries who have several health risks like older age, low oxygen levels, or heart or lung conditions.
StockholmAges 18 years+ - NCT05286957RecruitingPhase 2
MRD-guided immunotherapy plus chemo after lung cancer surgery
This trial tests whether adding a cancer-fighting immunotherapy (tislelizumab) and chemotherapy after surgery can lower the chance of lung cancer coming back. It uses “MRD” (measurable remaining disease) to help decide who may benefit the most after resection.
Zhengzhou, HenanAges 18–80 - NCT07446959Recruiting
Smallest effective dose of bupivacaine for chest surgery pain block
This trial tests the smallest amount of bupivacaine (a numbing medicine) needed to control pain after keyhole chest surgery. You will receive a nerve block before surgery, and the goal is to find the best dose with fewer side effects.
BursaAges 18 years+ - NCT07461779RecruitingPhase 4
Oxygen to the healthy lung during lung surgery
This study is testing whether giving extra oxygen to the lung that is not being operated on (the non-dependent lung) during surgery can reduce problems after lung surgery. If you are having lung surgery, this might help you recover better.
MadridAges 18 years+ - NCT07135284Recruiting
Testing the LibAirty System for Bronchiectasis at Home
This trial tests the LibAirty system, a device that helps clear mucus from your lungs, in people with bronchiectasis. Participants use the device at home to see how well it works in daily life.
Birmingham, AlabamaAges 21 years+ - NCT07459621Recruiting
App for smokers unsure about quitting
This study tests a smartphone app for people who smoke at least half a pack a day and are not sure they want to quit. The app helps them explore their feelings about smoking in a low-pressure way.
Portland, OregonAges 18 years+ - NCT07402707RecruitingPhase 4
Dexamethasone for acute asthma in children
This trial tests if a different steroid (dexamethasone) is as good as the usual steroid for treating children with asthma attacks in the Emergency Department. It aims to make treatment easier for children.
SheffieldAges 4–15
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,521 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.