Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,629 recruiting studies in this area right now.
By phase
- Not applicable4,297
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2310
- Phase 4208
- Phase 2/Phase 368
Top conditions
- Lung Cancer425
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama174
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas90
- Pennsylvania84
- Colorado71
Recruiting studies6,629 total
- NCT07169552RecruitingPhase 2
HC010 for first-line PD-L1 positive advanced lung cancer
This trial tests a new drug called HC010 as a first treatment for people with advanced non-small cell lung cancer that is PD-L1 positive. It aims to see if the drug can help shrink or control the cancer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06487078Recruiting
Study of Lorlatinib for untreated ALK-positive lung cancer
This study looks at how well and how safely the drug lorlatinib works in people with a certain type of advanced lung cancer (ALK-positive NSCLC) who have not had treatment for their advanced cancer yet. The goal is to see how effective it is in the real world.
Paris, ParisAges 18 years+ - NCT07717372Recruiting
CRP test for adults with respiratory infection in primary care
This trial tests whether a simple finger-prick test (C-reactive protein or CRP) can help doctors decide whether antibiotics are needed for adults with a cold or other respiratory infection. If you are an adult with recent symptoms and have not taken antibiotics yet, you may be able to join.
JakartaAges 18 years+ - NCT07716527Enrolling by invitation
Testing a web tool for lung cancer screening
This study is testing a new website-based tool to help people decide if they should get screened for lung cancer. You may be eligible if you are between 50 and 80 years old and currently smoke or recently quit.
New Brunswick, New JerseyAges 50–80 - NCT06348797RecruitingPhase 1
CAR-T Cells Targeting PD-L1 and DLL3 for Small Cell Lung Cancer
This trial tests a new CAR-T cell therapy that targets two proteins (PD-L1 and DLL3) on small cell lung cancer cells. It's for people whose cancer came back or got worse after standard chemotherapy, and it aims to see if the treatment is safe and works.
Chengdu, SichuanAges 18–70 - NCT06097910Recruiting
Watching multiple lung spots over time
This study is for people who have three or more tiny lung spots (called ground-glass nodules or GGNs) that have not changed in at least three months. The goal is to see if carefully monitoring these spots with regular CT scans is a safe and effective approach.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07687745RecruitingEarly Phase 1
Breathing exercises for healthy blood pressure during pregnancy
This trial tests whether a simple breathing exercise device can help keep your blood pressure healthy during pregnancy. You will use a small device 5-7 days a week and sync measurements with your smartphone.
Tucson, ArizonaAges 18–55 - NCT07616375RecruitingPhase 3
Safety Study of HSK31858 for Bronchiectasis
This study tests how safe an experimental inhaled medicine (HSK31858) is for people with non-cystic fibrosis bronchiectasis, a lung condition where airways are damaged and collect mucus. You can only join if you already completed a previous HSK31858 study.
Yixingcun, JiangxiAges 18 years+ - NCT07669779RecruitingPhase 2
Study of AK146D1 and AK112 for advanced lung cancer
This trial tests a combination of two experimental drugs, AK146D1 and AK112, for people with advanced non-small cell lung cancer that cannot be removed by surgery or treated with standard chemo-radiation. It aims to find out if this combination can shrink tumors or slow cancer growth.
Guangzhou, GuangdongAges 18–75 - NCT07637331Recruiting
Breathing Exercises and Brain Performance Study
This study tests whether special breathing muscle exercises can improve thinking and memory in healthy young adults. Researchers will track how the training affects your brain performance over time.
Bloomington, IndianaAges 18–40 - NCT07670013RecruitingPhase 2
SKB264 and glecirasib for advanced KRAS G12C lung cancer
This trial tests a new combination of two drugs (SKB264 and glecirasib) for people with advanced non-small cell lung cancer that has a specific genetic change called KRAS G12C. It aims to see if this combination can shrink tumors or slow their growth.
Hangzhou, ZhejiangAges 18–75 - NCT07682610Recruiting
Improving lung cancer screening in Kentucky clinics
This study works with healthcare teams to improve how lung cancer screening is done. It uses surveys and feedback to find better ways to help patients get screened.
Ashland, KentuckyAges 18–100 - NCT07611903Recruiting
Oxygen delivery methods during endoscopy procedure
This trial compares two different ways of delivering oxygen through your nose during an endoscopy procedure (ERCP, which examines your bile ducts and pancreas). The study tests whether one method keeps your oxygen levels safer or more comfortable than the other.
Kocaeli, UmuttepeAges 18–84 - NCT07587970Recruiting
Body Position and Oxygen Levels During Sedated Scope Procedures
This study tests whether your body position during recovery from sedated endoscopy (a camera procedure to examine your stomach and colon) affects your oxygen levels. The researchers want to find the best recovery position to keep your oxygen levels stable and safe.
Yinchuan, NingxiaAges 18 years+ - NCT07531901Recruiting
Testing Cough Sensitivity With a Handheld Inhaler Device
This study tests whether a handheld nebulizer (a device that turns liquid medicine into mist) can reliably measure how sensitive your cough reflex is. Researchers will have you inhale citric acid (a harmless substance similar to lemon juice) and record your cough response to see if this method works well.
Missoula, MontanaAges 18–89 - NCT07545304Recruiting
Testing MRI scans to help diagnose childhood lung disease
This study tests whether MRI (a safe imaging scan) can help doctors diagnose a specific type of lung disease in children. Your child would have an MRI scan to see if it gives doctors useful information before they do a procedure called a bronchoscopy.
SheffieldAges 5–17 - NCT07605078Recruiting
How Household Mold Affects Your Health
This study looks at whether mold and toxins in your home are connected to physical and mental health problems. Researchers will analyze dust samples you've already tested to understand these links better.
Richmond, VirginiaAges Any age - NCT07603921Recruiting
Local Pain Relief Injection During Lung Surgery
This study tests whether injecting a numbing medicine and anti-inflammatory steroid around the surgical area before lung surgery reduces pain after the procedure. If it works, it could help patients recover more comfortably after thoracoscopic lung surgery (minimally invasive lung surgery using small cameras).
Beijing, Beijing MunicipalityAges 18–64 - NCT07595341Enrolling by invitation
Breathing Training for Competitive Swimmers
This study tests whether a special breathing-exercise program can improve how well swimmers' lungs work and their swimming performance. Researchers will teach swimmers techniques to strengthen the muscles used for breathing and measure how it affects their ability to swim.
MadridAges 18 years+ - NCT07532733Recruiting
Sedation Safety During Minimally Invasive Heart Valve Procedure
This study examines how a specific sedative medication (dexmedetomidine) affects breathing and heart function during a minimally invasive procedure to replace a faulty heart valve. Researchers want to ensure the sedation is safe and effective for older adults.
BrusselsAges 60 years+ - NCT07495982Recruiting
Inflammation markers and CT scans in stable bronchiectasis
This study looks at whether certain blood tests and CT scans can help predict when someone with bronchiectasis might have a flare-up (worsening of symptoms). It may help doctors better understand and manage the condition.
SohagAges 18 years+ - NCT07538102Recruiting
Breathing Exercises for Ventilated ICU Patients
This study tests whether specialized breathing exercises can help strengthen the breathing muscle (diaphragm) in patients on breathing machines in the ICU. Researchers will measure changes in the diaphragm's thickness and function.
Çorum, CentreAges 18 years+ - NCT07512635RecruitingPhase 4
Nerve Block Pain Relief for Minimally Invasive Lung Surgery
This trial tests whether numbing medication injected around nerves in the chest can reduce pain and help patients recover faster after minimally invasive lung surgery. The goal is to improve how you feel after the procedure.
Sanming, FujianAges 18–65 - NCT07501923Recruiting
How heat exposure day and night affects human health
This study looks at how exposure to heat during the day, night, or both affects the health of healthy young adults. It may help understand how heat impacts the body and find ways to protect people from heat-related risks.
Hefei, AnhuiAges 18–30
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,629 recruiting pulmonology studies from the U.S. registry right now, out of 10,546 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.