Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,629 recruiting studies in this area right now.
By phase
- Not applicable4,297
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2310
- Phase 4208
- Phase 2/Phase 368
Top conditions
- Lung Cancer425
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama174
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas90
- Pennsylvania84
- Colorado71
Recruiting studies6,629 total
- NCT05846841Recruiting
Personalized quit-smoking support in primary care
This study tests a personalized tobacco (smoking) treatment plan delivered in primary care to help reduce cravings and smoking. It may help you quit or smoke less using options like nicotine patches/lozenges or varenicline, chosen to fit your needs.
St Louis, MissouriAges 18 years+ - NCT06638554Recruiting
Using video visits to help people get screened for lung cancer
This trial tests whether telehealth (video visits) can help more people get screened for lung cancer. It may be a good fit if you are between 50 and 80, have a history of smoking, and have not had a lung cancer screening in the last two years.
Philadelphia, PennsylvaniaAges 50–80 - NCT07419425RecruitingPhase 4
Help for Black adults to quit smoking
This study tests a program to help Black adults who smoke quit. It offers support and medication to help you stop smoking.
Phoenix, ArizonaAges 21 years+ - NCT07599462Recruiting
Better Communication for People Who Use Cigarettes and E-Cigarettes
This study tests new ways to talk with people about quitting or reducing cigarettes and e-cigarettes. Researchers want to understand what communication approaches work best for people using both products.
Chapel Hill, North CarolinaAges 18 years+ - NCT06789692Recruiting
Reducing tobacco use in people with HIV
This study combines a medication to help people stop smoking with a custom mobile app, all within the Swiss HIV Cohort Study. It's designed for people living with HIV who smoke and want to quit.
Basel, BaselAges 18 years+ - NCT06371482RecruitingPhase 2
Durvalumab plus chemoradiation for limited-stage small cell lung cancer
This trial tests adding the immunotherapy drug durvalumab to standard chemotherapy and radiation for limited-stage small cell lung cancer. The goal is to see if this combination helps control the cancer better than standard treatment alone.
Shijiazhuang, HebeiAges 18–75 - NCT06521515Recruiting
Lung ultrasound to predict weaning success
This study uses a lung ultrasound to predict which patients can safely come off a breathing machine. It's for older adults or those with heart/lung conditions who are at higher risk of needing the tube again.
Shanghai, Shanghai MunicipalityAges 18–100 - NCT05804188Recruiting
Testing safer breathing tube care in intubated children
This trial studies care during placing a breathing tube (tracheal intubation) in children having general anesthesia. It may help improve safety and outcomes around the breathing tube process.
Boston, MassachusettsAges Up to 16 years - NCT06106802RecruitingPhase 2
Testing lazertinib and tepotinib for EGFR lung cancer that progressed on lazertinib
This trial tests a combination of two targeted drugs, lazertinib and tepotinib, for people with advanced EGFR-mutant non-small cell lung cancer whose tumors show MET overactivity (high MET levels or MET gene copies) and have grown despite prior treatment with lazertinib. It aims to see if adding tepotinib can overcome that resistance.
Seoul, Gangnam-guAges 19 years+ - NCT06107374RecruitingPhase 2
New imaging for immunotherapy in advanced lung cancer
This trial tests a special imaging scan called [18F]-FARAG to see how well it shows the activity of immunotherapy in advanced NSCLC. The goal is to help doctors understand if the treatment is working earlier than standard scans.
Iowa City, IowaAges 18 years+ - NCT06105242Recruiting
Sex differences in CTEPH heart function and recovery
This study looks at how CTEPH (a type of high blood pressure in the lungs caused by blood clots) affects heart function differently in men and women. It uses heart ultrasounds and pressure measurements to see if recovery after surgery differs by sex.
Murray, UtahAges 18 years+ - NCT06102928Recruiting
Anlotinib plus Aumolertinib for first-line treatment of advanced EGFR-mutant lung cancer
This trial tests a combination of two targeted drugs (anlotinib and aumolertinib) as the first treatment for advanced lung cancer with a specific EGFR mutation (L858R). The goal is to see if the combination works better than standard care.
Kunming, YunnanAges 18 years+ - NCT07593027RecruitingPhase 1/Phase 2
Study of IMC-003 for pulmonary arterial hypertension
This trial tests a new drug called IMC-003 for people with pulmonary arterial hypertension (PAH). It aims to see if the drug can help improve symptoms and exercise ability when added to your current PAH medications.
Beijing, Beijing MunicipalityAges 18–75 - NCT07223762Enrolling by invitation
Comparing two types of laryngoscope blades for intubation
This trial compares two types of laryngoscope blades (the tool used to guide a breathing tube) to see which works better for routine intubations. If you are an adult scheduled for a planned breathing tube placement, you may be able to join.
Los Angeles, CaliforniaAges 18 years+ - NCT05443126RecruitingPhase 1/Phase 2
Testing a new RET drug for advanced lung cancer
This Phase 1/2 study tests lunbotinib, a new medicine that targets a specific lung-cancer change called RET. It aims to see how well it works and how safe it is for adults with advanced RET-altered non-small cell lung cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT05429463RecruitingPhase 3
Surgery-ready lung cancer treatment with immunotherapy plus chemo
This trial studies adding an immunotherapy drug (sintilimab) to standard chemotherapy before surgery for resectable squamous non-small cell lung cancer. It aims to shrink the tumor and improve outcomes, while still keeping the cancer operable.
Hangzhou, ZhejiangAges 18–75 - NCT06531798RecruitingPhase 4
Safety study of Breztri aerosphere in Indian COPD patients
This study tests a medication called Breztri aerosphere (a triple-combination inhaler) to see how safe and well-tolerated it is in Indian patients with COPD who have had recent flare-ups. It may help people who need better control of their breathing symptoms.
Dalgate, DrugjanAges 18 years+ - NCT05481723RecruitingPhase 3
Lung ultrasound to guide fluid and blood pressure during surgery
This Phase 3 study tests whether using a lung ultrasound scan during surgery can better guide blood pressure and fluid needs. It may help stabilize patients during long operations and reduce complications related to poor circulation or fluid balance.
AmiensAges 18 years+ - NCT06491862Recruiting
Lung cancer care after chemo in Brazil
This study looks at how doctors in Brazil treat non-squamous non-small cell lung cancer after platinum chemotherapy stops working. It aims to understand real-world outcomes and help improve future care.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT07142668Recruiting
How cigarette cost and availability affect tobacco buying
This study looks at how changing cigarette prices and availability affects what and how much tobacco people buy. It may help inform future policies that aim to reduce smoking.
Buffalo, New YorkAges 21 years+ - NCT05413122RecruitingPhase 2/Phase 3
Smoking quit support for adults living with HIV in South Africa
This trial tests smoking-cessation interventions to help people living with HIV quit smoking or smoke less. You may be eligible if you smoke, are actively engaged in HIV treatment, and can follow the study for about a year.
Soweto, GautengAges 18 years+ - NCT07448194RecruitingPhase 1
Safety study of HW241045 in healthy adults
This trial tests the safety of a new drug called HW241045 in healthy volunteers. It helps doctors understand how the drug affects the body and if it causes any side effects.
BeijingAges 18–55 - NCT07445269Enrolling by invitation
Breathing muscle warm-up for athletes
This study looks at whether warming up your breathing muscles before exercise can help make them stronger during both fast, explosive workouts (like sprinting) and longer, steady endurance exercise (like jogging). It might be a good option for young athletes who want to see if a simple warm-up can boost their performance.
ÇorumAges 14–30 - NCT07047430Recruiting
Air quality near Sea-Tac airport and children's asthma
This study looks at how air quality near the airport affects children with asthma. Participating families help researchers understand if certain actions can reduce asthma flare-ups.
Seattle, WashingtonAges 6–12
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,629 recruiting pulmonology studies from the U.S. registry right now, out of 10,546 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.