Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,193 recruiting studies in this area right now.
By phase
- Not applicable6,797
- Phase 2515
- Phase 1257
- Phase 3244
- Phase 4212
- Phase 1/Phase 297
- Phase 2/Phase 371
Top conditions
- Depression421
- Anxiety414
- Alzheimer Disease340
- Autism Spectrum Disorder257
- Dementia227
- Mild Cognitive Impairment199
- Schizophrenia192
- Major Depressive Disorder189
- Cognitive Impairment157
- Insomnia152
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Suicidal Ideation92
- Mental Health91
- Anxiety Disorders85
Leading sponsors
- VA Office of Research and Development102
- Yale University94
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University64
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania51
- Karolinska Institutet50
Where studies are running
- California529
- New York268
- Massachusetts263
- Texas224
- Maryland177
- Pennsylvania175
- Florida152
- Alabama117
- Arizona117
- Connecticut112
Recruiting studies8,192 total
- NCT07192042Recruiting
Testing a device to check sleep breathing in schizophrenia
This trial uses a non-wearable device to assess sleep-disordered breathing in people with schizophrenia who are hospitalized. It aims to understand if this easy method can help monitor sleep issues.
New Taipei CityAges 20–70 - NCT06995885Enrolling by invitation
A study to improve tracking of opioid use in the fentanyl era
This study aims to develop a better tool for recalling and tracking opioid use patterns, especially with fentanyl. It may help people who use opioids outside of medical settings to more accurately report their use.
Baltimore, MarylandAges 18–99 - NCT07644949Recruiting
Stress-Reduction Program for Social Service Workers
This study tests whether a self-help program called Self-Help Plus can reduce stress and improve well-being in social service workers. You would attend sessions and complete questionnaires over the study period.
IstanbulAges 18 years+ - NCT06229210RecruitingPhase 3
Lumateperone safety study for children with schizophrenia, bipolar, or autism
This trial tests a medication called lumateperone for children and teens with schizophrenia, bipolar disorder, or autism spectrum disorder. It aims to see if the medicine is safe and tolerable over time.
Phoenix, ArizonaAges 5–17 - NCT06762444Recruiting
Bump the lump: A treatment for throat lump feeling
This study tests a treatment for people who feel like there's a lump in their throat, called globus pharyngeus. If you have this sensation but no swallowing problems, you may be able to join.
Winston-Salem, North CarolinaAges 18 years+ - NCT07632248Recruiting
Digital Game for Early Eating Disorder Prevention
This study tests FlexED, a smartphone game designed to help young women who are worried about their weight and showing early signs of eating disorder behaviors—like extreme dieting, binge eating, or purging—before these behaviors become a full disorder. The goal is to see if this fun, interactive approach can help prevent the condition from getting worse.
Durham, North CarolinaAges 15–25 - NCT06655883RecruitingPhase 3
Testing suvorexant for insomnia in people with opioid use disorder
This study tests whether the sleep medication suvorexant (Belsomra) can help people with opioid use disorder who also have trouble sleeping. If you are stable on medication for opioid use disorder and have not used opioids in the last month, this trial may be an option for you.
Garden Grove, CaliforniaAges 18–70 - NCT06548490RecruitingPhase 2
Semaglutide for Opioid Use Disorder
This study tests whether a once-weekly injection of semaglutide (a GLP-1 receptor agonist) can reduce opioid use in people who are already on buprenorphine or methadone but still using opioids. It lasts about 19 weeks.
Baltimore, MarylandAges 18–75 - NCT07179614Recruiting
Kentucky women's overdose recovery program
This trial tests a support program for women in Kentucky jails who have opioid or stimulant use disorder. It aims to reduce overdose risk after release by connecting them with community support.
Harlan, KentuckyAges 18 years+ - NCT07099053Recruiting
Brain scan study for aging adults in Baltimore
This study uses a special brain scan (amyloid PET) to look at brain changes in healthy older adults. It may help researchers learn more about aging and memory loss.
Baltimore, MarylandAges 55–110 - NCT06566664Enrolling by invitation
Peripheral neurostimulation for improving nerve block placement in upper limb surgery
This study looks at using peripheral neurostimulation to improve the placement of nerve blocks for upper limb surgery. It may help you get better pain control during and after your operation.
Stanford, CaliforniaAges 18 years+ - NCT07191561Recruiting
Liver fat and alcohol use disorder study
This trial looks at how the liver processes fat in people with alcohol use disorder. It may help find better ways to treat liver problems related to drinking.
Bethesda, MarylandAges 18–100 - NCT05384158Recruiting
Testing a computer game for low mood, low pleasure, or anxiety
This trial looks at how a computer-based task performs when someone is dealing with depression-like symptoms, such as low mood, low interest/pleasure, or anxiety that affects daily functioning. You might find it helpful if you fit their symptom and safety requirements and are comfortable with computer tasks and (for some parts) MRI scanning.
Roanoke, VirginiaAges 25–50 - NCT06676059Recruiting
Substance use monitoring study with a smartphone app
This study uses a smartphone app and daily surveys to track alcohol or drug use. It aims to create a database for future research on addiction patterns and recovery.
Baltimore, MarylandAges 18–120 - NCT07169630RecruitingPhase 1
PET scan study for Alzheimer's or mild cognitive impairment
This study uses a special PET scan to look at a brain protein called PDE4 in people with Alzheimer's disease or mild cognitive impairment. It may help researchers understand how this protein is involved in memory and thinking problems.
Bethesda, MarylandAges 50–100 - NCT07424404RecruitingPhase 3
Long-term safety trial for teens with schizophrenia or autism irritability
This trial looks at the long-term safety of KarXT, a medication for schizophrenia, and KarX-EC for irritability related to autism in teenagers. It is for teens who have already completed the main part of a previous study without serious side effects.
Dothan, AlabamaAges 5–17 - NCT07227454RecruitingPhase 3
Esketamine for teens with severe depression and suicidal thoughts
This trial tests if esketamine (a nasal spray) can quickly reduce symptoms of major depression and suicidal thoughts in teenagers who need urgent hospital care.
Birmingham, AlabamaAges 12–17 - NCT07188506Recruiting
Youth suicide risk: reducing risk factors in young people
This study looks at suicide risk factors in young people with mood disorders (like depression or bipolar disorder) and tests ways to reduce those risks. It may help if you are between 18 and 25, have a mood disorder, and can undergo an MRI.
Roma, RMAges 18–25 - NCT07716098RecruitingPhase 3
Esketamine nasal spray for treatment-resistant depression
This study tests esketamine nasal spray versus a placebo in adults with depression that has not improved after trying at least two other antidepressants. It aims to see if the spray can help when standard pills have not worked.
Redlands, CaliforniaAges 18 years+ - NCT06801210Enrolling by invitation
Long-term health after elite weight-sensitive sports
This study looks at the long-term health of former elite athletes from sports that focus on weight, like gymnastics or rowing. Researchers want to understand how retiring from such sports affects your body and mind over time.
OsloAges 18 years+ - NCT05183152RecruitingTeam says not enrolling
Non-invasive brain signal control for assistive devices
This study tests an assistive device that you control using signals from the brain and muscles without surgery. It may help people with movement problems communicate or operate devices using gentle, non-invasive sensing.
Austin, TexasAges 18–80 - NCT04557891RecruitingTeam says not enrolling
Low-intensity ultrasound for generalized anxiety disorder
This trial tests a non-drug brain treatment using low-intensity focused ultrasound to reduce symptoms of generalized anxiety disorder (GAD). It may help if your anxiety has been moderate to severe and you’ve already tried standard medications without enough relief.
Los Angeles, CaliforniaAges 18–65 - NCT05048251RecruitingTeam says not enrolling
Targeted brain stimulation for OCD with contamination symptoms
This study tests a personalized brain-stimulation approach to help people with obsessive-compulsive disorder (OCD) focused on contamination worries. If you have the “contamination” type of OCD and meet the safety and medication rules, you may be able to join and see whether this targeted treatment reduces symptoms.
Belmont, MassachusettsAges 18–55 - NCT04627415RecruitingTeam says not enrolling
Early support program for ADHD symptoms in preschool children
This trial tests an early intervention program for young children (about ages 3 to 5) with clinically significant attention and behavior symptoms. It may help by targeting ADHD-related difficulties seen at home and school.
Bethlehem, PennsylvaniaAges 3–5
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,193 recruiting psychiatry studies from the U.S. registry right now, out of 13,230 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Immune system & allergy
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- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.