Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,769 recruiting studies in this area right now.
By phase
- Not applicable6,417
- Phase 2493
- Phase 1249
- Phase 3236
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 368
Top conditions
- Anxiety386
- Depression382
- Alzheimer Disease337
- Autism Spectrum Disorder240
- Dementia224
- Mild Cognitive Impairment193
- Schizophrenia185
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder142
- Opioid Use Disorder141
- Stress117
- PTSD106
- Mental Health99
- Autism95
- Mild Cognitive Impairment (MCI)88
- Suicidal Ideation87
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital76
- Stanford University69
- Assistance Publique - Hôpitaux de Paris63
- Johns Hopkins University61
- University of California, Los Angeles58
- The University of Hong Kong52
- University of Pennsylvania52
- Karolinska Institutet49
Where studies are running
- California517
- Massachusetts263
- New York255
- Texas209
- Maryland174
- Pennsylvania169
- Florida145
- Alabama118
- Arizona110
- Illinois104
Recruiting studies7,769 total
- NCT06995885Enrolling by invitation
A study to improve tracking of opioid use in the fentanyl era
This study aims to develop a better tool for recalling and tracking opioid use patterns, especially with fentanyl. It may help people who use opioids outside of medical settings to more accurately report their use.
Baltimore, MarylandAges 18–99 - NCT07459647RecruitingPhase 2
Long-term study of ML-007C-MA for schizophrenia
This trial tests a new drug, ML-007C-MA, for adults with schizophrenia who may benefit from ongoing treatment. It aims to see how safe and effective the drug is over a longer period.
Little Rock, ArkansasAges 18–65 - NCT06811181Recruiting
Study of what affects family doctors' handling of burnout
This study looks at the personal and social factors that affect how family doctors handle burnout. It aims to learn what supports or makes it harder for general practitioners to manage their own burnout, with the hope of improving doctor well-being.
NantesAges 18 years+ - NCT06860607RecruitingPhase 1
Environment and Alcohol: A Pilot Study
A pilot study exploring the interaction between environment and alcohol consumption in individuals with alcohol use disorder (AUD), using smartphone-based ecological momentary assessment (EMA).
Baltimore, MarylandAges 21–100 - NCT07358598Recruiting
Eye movement and thinking in older adults
This study looks at how eye movements relate to thinking abilities in people aged 65 and older. It may help understand how the brain changes with age.
Kaohsiung CityAges 65 years+ - NCT07661563Recruiting
Alcohol support via text and chat in the emergency department
This study tests whether a friendly computer chat program, combined with text message reminders, can help reduce risky drinking in people who visit the emergency department. It aims to see if this approach is easier to use and helps you cut back on alcohol.
Palo Alto, CaliforniaAges 18–65 - NCT07425405Recruiting
Screen time and surgery anxiety in young children
This study looks at how daily screen time affects anxiety in children aged 2 to 5 years before a planned surgery. It aims to find if more screen time is linked to more anxiety, which could help prepare children better for surgery.
Istanbul, küçükçekmeceAges 2–5 - NCT05233111Enrolling by invitation
Exposure therapy to reduce PTSD after spinal cord injury
This trial compares a specific type of talk therapy (brief prolonged exposure) versus standard care to reduce post-traumatic stress symptoms after a spinal cord injury. If you qualify, you may get extra support targeted at PTSD symptoms during inpatient rehab.
Dallas, TexasAges 18 years+ - NCT07767396Recruiting
Eye movement technique for reducing intrusive trauma memories
This study tests whether a specific eye movement technique, done at home on a computer, can help reduce distressing, intrusive memories after trauma. If you've been having frequent, unwanted trauma memories, this could help you gain better control over them.
Xi'an, ShaanxiAges 18–50 - NCT06073990Enrolling by invitation
Insomnia help for adults 50 and older
This trial tests a short talk therapy that helps improve sleep without medication. It focuses on older adults who have had trouble sleeping for at least 3 months.
Tainan, TaiwanAges 50 years+ - NCT07099053Recruiting
Brain scan study for aging adults in Baltimore
This study uses a special brain scan (amyloid PET) to look at brain changes in healthy older adults. It may help researchers learn more about aging and memory loss.
Baltimore, MarylandAges 55–110 - NCT07177352RecruitingPhase 3
Screening for Roche Alzheimer's studies
This is a screening study to find people who might be eligible for other Alzheimer's drug studies run by the same company. It helps match you to a treatment trial if you qualify.
Birmingham, AlabamaAges 50–90 - NCT06520592Enrolling by invitation
Augmented reality to help CPAP use for sleep apnea
This study tests whether using augmented reality (AR) can make it easier for people with moderate to severe sleep apnea to use a CPAP machine, which helps keep their airway open during sleep. It aims to see if AR can improve comfort and adherence to CPAP therapy.
Tainan, TaiwanAges Any age - NCT07498426RecruitingPhase 3
Study of NIO752 for progressive supranuclear palsy
This trial tests a new medicine called NIO752 for people with progressive supranuclear palsy (PSP), a condition that affects movement, balance, and thinking. The goal is to see if it can help slow the disease's progression.
Scottsdale, ArizonaAges 41–81 - NCT07424404RecruitingPhase 3
Long-term safety study of a medication for psychiatric disorders in children and teens
This study tests a combination medicine (xanomeline and trospium chloride) to see if it is safe and tolerable over a longer period for children and adolescents with psychiatric disorders, especially those with autism-related irritability. It may help families understand if this treatment can be used beyond the initial study period.
Dothan, AlabamaAges 5–17 - NCT07863440Recruiting
Digital therapy for gambling disorder
This trial tests a smartphone-based therapy program to help people stop gambling. It also involves a family member, like a parent, spouse, or sibling, to support the patient during treatment.
Jakarta Pusat, Jakarta Special Capital RegionAges 18 years+ - NCT07721467RecruitingPhase 2
Cognitive training with psilocybin for brain flexibility
This study tests whether combining a brain-training program with a psychedelic drug called psilocybin can boost the brain's ability to change and adapt. It may help improve thinking and memory.
Baltimore, MarylandAges 65–120 - NCT02568878RecruitingPhase 3
Creatine to help depression and anxiety in meth users
This trial studies whether creatine can reduce depression and anxiety symptoms in people who currently use methamphetamine and also have depression and anxiety. It may help by improving mood and anxiety scores over the course of the study.
Missoula, MontanaAges 18–59 - NCT02889016Recruiting
Markers study for children with PANS and healthy controls
This study looks at physical, immune, and brain-related “markers” in children with PANS and compares them with healthy children. It may help doctors understand what is happening in PANS and how to recognize it more clearly early on.
Palo Alto, CaliforniaAges 4–18 - NCT02951754RecruitingPhase 4
Methylphenidate for adults with ADHD
This trial tests whether methylphenidate (a stimulant medicine) helps adults with attention-deficit/hyperactivity disorder (ADHD). It is checking safety and effectiveness for people who can take the immediate-release form of the medicine.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT03152630Recruiting
Vascular dementia check-up and risk diagnosis study
This study aims to find early ways to diagnose “vascular dementia,” which happens when blood vessel problems affect thinking and memory. It may help by testing how well certain health risk factors and medical information can predict who might be developing it.
TaipeiAges 65 years+ - NCT03222375Recruiting
Home treatment for autism using special sound and imaging devices
This trial studies a home-based treatment for autism (or related conditions) using specially designed sound, image, and electromagnetic devices. It aims to see whether this personalized “treatment code” and device approach can improve autism-related skills and behaviors.
Louisville, KentuckyAges 1 month–21 years - NCT03466619Recruiting
Penile implant surgery for erectile dysfunction when medicines fail
This trial looks at using a penile implant pump to help erections in people whose erectile dysfunction can’t be fixed with standard medicine or can’t safely take it. It may help if pills or other treatments have not worked for you, but it also requires the ability to use the device correctly and safely.
Cairo, ElgharbiaAges 18–80 - NCT01194648Recruiting
HIFU treatment for early prostate cancer
This trial studies a focused ultrasound treatment called HIFU for prostate cancer that appears limited to the early stages. It aims to treat cancer within the prostate while avoiding treatment spread to lymph nodes or distant organs.
London, EnglandAges Up to 90 years
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,769 recruiting psychiatry studies from the U.S. registry right now, out of 12,243 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.