Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06805682Recruiting
Study of young children in child protective care
This study follows young children (under 3.5 years) who are under child protective services, to better understand their health and needs. It aims to improve care for vulnerable children.
Évreux, FranceAges birth–3.5 years - NCT06122298Recruiting
Study on gambling, emotions, and rewards
This study looks at how gambling affects emotions and the brain's reward system. It compares people with gambling problems to healthy volunteers to better understand gambling addiction.
BronAges 18–65 - NCT05180344Recruiting
Personalized phone support for suicidal thoughts or actions
This study tests a personalized mobile (phone) program to help people who have had suicidal thoughts or actions in the past month. It aims to see if the approach is safe, acceptable, and possibly helpful in reducing risk and distress.
Providence, Rhode IslandAges 18–26 - NCT05065450Recruiting
Testing whether brain stimulation improves memory in epilepsy
This trial looks at ways to improve memory by targeting specific deep brain areas in people with epilepsy. You may be eligible if you are already scheduled for long-term video monitoring with implanted depth electrodes in the memory-related regions (amygdala, hippocampus, and nearby areas).
St Louis, MissouriAges 18–75 - NCT06499051Recruiting
Study of French sexual offenders in legal care
This study looks at the health and background of people in France who have committed sexual offenses and are involved with the legal system. The goal is to better understand their needs and how to help them.
BronAges 18 years+ - NCT06793397RecruitingPhase 3
Study of an experimental psychedelic-like drug for depression (CYB003)
This study tests an investigational medication (CYB003) for people with major depression whose current antidepressant isn't working well enough. It looks at whether this treatment can help improve depression symptoms.
Birmingham, AlabamaAges 18–85 - NCT06803329Recruiting
Social connection program to prevent suicide in LGBTQ+ veterans
This study tests a program called Qnnections designed to help LGBTQ+ and other minority veterans feel more connected and reduce suicide risk. It is for veterans who have had recent suicidal thoughts or behaviors and are already working with a mental health provider.
San Diego, CaliforniaAges 18 years+ - NCT03642028RecruitingPhase 4
Sleep medicine study for PTSD-related sleep problems
This trial tests suvorexant, a sleep medicine, to help improve sleep disturbance in people with PTSD. It’s designed for adults who have had PTSD symptoms for at least a few months and also have insomnia.
Long Beach, CaliforniaAges 18–75 - NCT05701111Recruiting
School-based treatment for teens with trauma symptoms
This study tests a school-based approach to help teens who have experienced trauma and now have post-trauma symptoms. It also collects emotional and physical (biologic) information to understand how treatment may help.
Palo Alto, CaliforniaAges 11–17 - NCT06795451RecruitingPhase 1/Phase 2
Spinal stimulation for depression: a clinical trial
This study tests if a non-invasive spinal stimulation device can improve depression symptoms. It is for people currently taking an antidepressant for at least 8 weeks but still experiencing depression.
Mason, OhioAges 18–60 - NCT06793735Recruiting
Virtual reality app for memory and thinking problems
This trial tests a virtual reality app you can use at home to help with early memory or thinking problems. It may be an option if you have mild cognitive impairment or notice your thinking is slowing down.
Messina, ItalyAges 40–80 - NCT06802094Recruiting
Balance and movement strategies in children with DCD
This study compares how children with and without Developmental Coordination Disorder (a condition affecting motor skills) move their bodies during balance tasks. Researchers will use special tests and motion sensors to see different movement patterns, which could help design better therapy for kids with balance or coordination challenges.
Diepenbeek, LimburgAges 7–12 - NCT06802913RecruitingEarly Phase 1
Inhaled melatonin for sleep problems in older adults
This trial tests a new inhaled form of melatonin to help adults aged 55 and older with insomnia fall asleep faster. It compares the inhaled melatonin to a placebo to see if it improves sleep and is safe.
Macquarie Park, New South WalesAges 55 years+ - NCT06799351RecruitingPhase 2/Phase 3
Gut bacteria and nerve pain after chemo
This study looks at how bacteria in your gut (microbiome) might be linked to nerve pain from chemotherapy. It is for people who are already in the OzoParQT trial and will provide a stool sample to help understand this connection.
Las Palmas, Las PalmasAges 18 years+ - NCT06799117Recruiting
Decision Support for Opioid Addiction Treatment
This study tests a new way to help people in the emergency department who have moderate to severe opioid use disorder. It looks at using a decision-support tool to guide treatment choices.
Guilford, ConnecticutAges 18 years+ - NCT06801210Enrolling by invitation
Long-term health after elite weight-sensitive sports
This study looks at the long-term health of former elite athletes from sports that focus on weight, like gymnastics or rowing. Researchers want to understand how retiring from such sports affects your body and mind over time.
OsloAges 18 years+ - NCT06800937Recruiting
Sphingolipid study in women with anorexia nervosa
This trial looks at certain fats in the blood (called sphingolipids) in women with anorexia nervosa. Finding patterns might help understand the illness better and could lead to new ways to help.
Oggebbio, VerbaniaAges 18 years+ - NCT06800898Recruiting
Orexin gene study in anorexia nervosa
This study looks at a gene called orexin in women with anorexia nervosa. It aims to understand how this gene might be related to the condition, which could lead to better treatments.
Oggebbio, VerbaniaAges 18 years+ - NCT06800807Recruiting
Beliefs about thinking in teens with eating disorders
This study looks at how teens with eating disorders think about their own thoughts (called metacognition). It compares their responses to a group of teens without eating disorders to better understand the role of certain beliefs in these conditions.
Oggebbio, VerbaniaAges 12–17 - NCT06803485RecruitingPhase 4
Comparing two antidepressants for pain-related somatic symptom disorder
This trial tests whether venlafaxine or dosulepin works better for people whose main problem is pain from a condition called somatic symptom disorder. You may join if you are 18–65, have not recently taken similar medication, and do not have other serious health issues.
Bhubaneswar, OdishaAges 18–65 - NCT06795126Enrolling by invitation
Virtual reality for pain and anxiety in kids getting IVs
This study tests if a virtual reality game called Little NIRVANA can help reduce pain and anxiety in children getting an IV. It's for kids ages 2 to 8 in the emergency department.
Columbus, OhioAges 2–8 - NCT06801041RecruitingPhase 2
Psilocybin therapy for anxiety or depression in cancer survivors
This trial tests if a single dose of psilocybin, given with therapy, can help cancer survivors who struggle with anxiety or depression. You would travel to MD Anderson for treatment and follow-up, and must stop certain medications beforehand.
Houston, TexasAges 18 years+ - NCT06801925Enrolling by invitation
Voice Chatbot for Depression Screening
This trial tests a voice chatbot that uses artificial intelligence to screen for depression. It aims to see if the chatbot is effective and easy to use.
LondonAges 18–65 - NCT06798636RecruitingEarly Phase 1
Psilocybin and mental imagery for young people who self-harm
This study tests whether a single dose of psilocybin (the active ingredient in magic mushrooms) combined with a mental imagery therapy can help reduce self-harm thoughts and behaviors in people ages 16–25. You would receive the drug in a safe clinic setting and complete several therapy sessions and questionnaires over a few weeks.
LondonAges 16–25
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.