Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06575751RecruitingPhase 2
Study of cannabidiol and cannabis concentrate users
This study looks at how cannabidiol (a compound in cannabis) affects people who regularly use strong cannabis concentrates like wax, shatter, or oil. It may help understand if using CBD can change how cannabis affects the body or help with cannabis use disorder.
Aurora, ColoradoAges 25–60 - NCT06568419Recruiting
Online therapy for mental health and work
This trial tests an online program to help people on sick leave due to anxiety or depression return to work. You would receive therapy through a secure website while staying with your regular mental health care team.
Oslo, BærumAges 18–65 - NCT06570109Enrolling by invitation
Risk and outcomes of frailty in Alzheimer's dementia
This study looks at how frailty affects people newly diagnosed with Alzheimer's dementia. It aims to understand risk factors and outcomes to help improve care.
AalborgAges 65 years+ - NCT06571916Recruiting
Brief skills for safer living
This study tests a short therapy program that teaches practical skills to help people cope with thoughts of suicide. It aims to see if learning these skills can make a difference in staying safe.
Toronto, OntarioAges 18 years+ - NCT06582199Recruiting
Personalized Alzheimer's study using brain scans and spinal fluid
This study looks at how to better predict and understand Alzheimer's disease by using advanced brain scans and spinal fluid tests. It aims to find ways to identify people who stay healthy longer despite risk factors.
ParisAges 50–90 - NCT06568081Recruiting
Studying a therapy for paranoia in psychosis
This trial tests a therapy for people with psychosis who also experience paranoia. It aims to see if the therapy works and whether it's cost-effective in routine care.
LondonAges 18 years+ - NCT06580860Recruiting
Brain health study for young people with early psychosis
This study looks at brain scans and other health information to understand mental health conditions better. You may be able to join if you are a young adult or teen with early signs of mental health changes.
Changsha, HunanAges 13–35 - NCT06573476Recruiting
Smartphone app and peer coach for opioid treatment
This study tests whether a smartphone app and support from a peer recovery coach can help Black and Latinx individuals with opioid use disorder start buprenorphine treatment. The goal is to reduce overdose deaths and address racial gaps in care.
New York, New YorkAges 18–99 - NCT06580561Recruiting
Exercise and insomnia treatment for knee pain
This study combines a gentle exercise program with a treatment for insomnia to see if it helps older adults with knee osteoarthritis feel less pain and sleep better. You will attend group exercise classes and receive sleep coaching.
Ann Arbor, MichiganAges 50 years+ - NCT06574360RecruitingPhase 2
Study of a dual-target drug for hard-to-treat schizophrenia
This trial tests an experimental combination treatment that targets two different brain receptors (sigma-1 and NMDA) to see if it can improve symptoms in people with schizophrenia that hasn't responded well to standard antipsychotics.
TaichungAges 18–65 - NCT06570889RecruitingPhase 3
Vitamin D in pregnancy to prevent early childhood asthma
This trial tests if taking extra vitamin D during pregnancy can prevent asthma in young children. It is for pregnant women in Denmark who already have certain healthy fat levels in their blood.
Gentofte MunicipalityAges 18–45 - NCT06572683Enrolling by invitation
Novel TMS for hard-to-treat depression
This trial tests a new type of transcranial magnetic stimulation (TMS) for people with severe depression that hasn't improved with multiple medications or therapy. It uses a different frequency pattern to target brain circuits.
Los Angeles, CaliforniaAges 21–75 - NCT06582121Recruiting
Sleep disorders in early and advanced Parkinson's disease
This study looks at sleep problems in people with Parkinson's disease, people with REM sleep behavior disorder (a condition that causes acting out dreams), and healthy volunteers. The goal is to understand how sleep is affected in early and full Parkinson's disease.
Clermont-FerrandAges 18 years+ - NCT06577779RecruitingPhase 4
Testing Jornay PM for adult ADHD symptoms into the evening
This study tests if Jornay PM, a long-acting ADHD medication, helps control symptoms, focus, and emotions throughout the day and into the early evening in adults with ADHD. It is an open-label study, meaning everyone knows they are getting the medication, and then they are randomly assigned to different observation groups.
New York, New YorkAges 18–60 - NCT06575894Enrolling by invitation
Mental health program for home visiting staff in Iowa and Indiana
This trial tests a program to improve mental health support for staff and volunteers in home visiting programs in Iowa and Indiana. It aims to help you feel better and more supported at work.
Indianapolis, IndianaAges 18 years+ - NCT06577636RecruitingPhase 2
Dreaming with anesthesia for post-traumatic stress disorder
This study tests whether using anesthesia to induce dreaming can help people with post-traumatic stress disorder (PTSD). It aims to see if a therapy session under anesthesia can reduce PTSD symptoms and improve well-being.
Stanford, CaliforniaAges 18–70 - NCT06576726Recruiting
Tracking tic disorder in teens over time
This study follows teens with chronic tic disorders (like Tourette syndrome) for a few years to understand how their symptoms and social life change. It also looks at brain signals using EEG, but you can join the main study even if you can't do the EEG part.
Nashvile, TennesseeAges 11–17 - NCT06578429Recruiting
Deep TMS for methamphetamine use disorder
This study uses a type of brain stimulation called deep TMS to see if it can help people with methamphetamine use disorder reduce their cravings and use. You would receive daily magnetic pulses to specific brain areas over several weeks.
Palo Alto, CaliforniaAges 25–75 - NCT06567210Recruiting
Insomnia treatment and emotional memory regulation for mental health
This study tests whether treating insomnia can help regulate emotional memories overnight, which may reduce the risk of developing or worsening mental health conditions. You may be eligible if you have both insomnia and some anxiety symptoms.
Macquarie Park, New South WalesAges 18–45 - NCT06581302Recruiting
Magnetic seizure therapy for psychotic disorders
This trial tests magnetic seizure therapy (MST) as a treatment for people with schizophrenia or other psychotic disorders. It aims to see if MST can help reduce symptoms like hallucinations or delusions.
Shanghai, Shanghai MunicipalityAges 18–55 - NCT06579183Recruiting
Health products for better mood and sleep
This trial tests health products to see if they can improve mood and sleep quality. It is for adults who are generally healthy and not currently struggling with mental health conditions.
Hong Kong, Hong KongAges 18–65 - NCT06578845Recruiting
HappyMums app for depression during pregnancy
This trial tests a mobile app called HappyMums to see if it can help pregnant people who feel depressed or have risk factors for depression. The app is designed to provide support and may improve your mood during pregnancy.
ZagrebAges 18 years+ - NCT06569303Recruiting
Filipino family health study for parents of children 8–12
This study offers a free parenting program for Filipino families with children ages 8–12 to help strengthen family bonds and manage challenges together. It is designed to understand what works best for your community.
Pasadena, CaliforniaAges 8 years+ - NCT06573671Enrolling by invitation
Histiocytosis in people who inject drugs
This trial looks at a condition called PVP-histiocytosis, which can happen in people who inject drugs made from tablets containing polyvinylpyrrolidone (PVP). The goal is to study these cases to better understand the condition.
Tampere, PirkanmaaAges 18–70
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.