Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06573034Recruiting
Standing meditation study for young adults with stress
This study tests if a gentle standing meditation practice (called Daoist Zhanzhuang) can help young adults feel better and handle stress. You would practice for 30 minutes at a time and be followed for a year.
Charlotte, North CarolinaAges 18–25 - NCT06577636RecruitingPhase 2
Dreaming with anesthesia for post-traumatic stress disorder
This study tests whether using anesthesia to induce dreaming can help people with post-traumatic stress disorder (PTSD). It aims to see if a therapy session under anesthesia can reduce PTSD symptoms and improve well-being.
Stanford, CaliforniaAges 18–70 - NCT06578429Recruiting
Deep TMS for methamphetamine use disorder
This study uses a type of brain stimulation called deep TMS to see if it can help people with methamphetamine use disorder reduce their cravings and use. You would receive daily magnetic pulses to specific brain areas over several weeks.
Palo Alto, CaliforniaAges 25–75 - NCT06582706RecruitingPhase 1/Phase 2
Vitamin B3 (niacin) for Alzheimer's disease
This study tests if nicotinic acid (a form of vitamin B3) can help people with mild to moderate Alzheimer's disease. It involves taking a daily pill, having a lumbar puncture, and regular check-ups to see if the vitamin improves thinking and memory.
Indianapolis, IndianaAges 60–85 - NCT06577779RecruitingPhase 4
Testing Jornay PM for adult ADHD symptoms into the evening
This study tests if Jornay PM, a long-acting ADHD medication, helps control symptoms, focus, and emotions throughout the day and into the early evening in adults with ADHD. It is an open-label study, meaning everyone knows they are getting the medication, and then they are randomly assigned to different observation groups.
New York, New YorkAges 18–60 - NCT06567210Recruiting
Insomnia treatment and emotional memory regulation for mental health
This study tests whether treating insomnia can help regulate emotional memories overnight, which may reduce the risk of developing or worsening mental health conditions. You may be eligible if you have both insomnia and some anxiety symptoms.
Macquarie Park, New South WalesAges 18–45 - NCT06575075RecruitingPhase 1/Phase 2
Ketamine study for OCD
This study tests a form of ketamine called RR-HNK as a possible new treatment for OCD. It is for people who have not gotten enough relief from standard treatments or chose not to take them.
Palo Alto, CaliforniaAges 18–65 - NCT06569394RecruitingPhase 2
Testing CBD in young adults who use cannabis heavily
This study tests whether cannabidiol (CBD) can help young adults who use cannabis heavily but aren't looking to quit. You'll take a CBD pill and see if it changes your cannabis use or related symptoms.
Aurora, ColoradoAges 18–25 - NCT06568419Recruiting
Online therapy for mental health and work
This trial tests an online program to help people on sick leave due to anxiety or depression return to work. You would receive therapy through a secure website while staying with your regular mental health care team.
Oslo, BærumAges 18–65 - NCT06571916Recruiting
Brief skills for safer living
This study tests a short therapy program that teaches practical skills to help people cope with thoughts of suicide. It aims to see if learning these skills can make a difference in staying safe.
Toronto, OntarioAges 18 years+ - NCT06576323Recruiting
Support for mothers with opioid use disorder and babies in the NICU
This study aims to improve care for mothers with opioid use disorder and their babies with neonatal abstinence syndrome. Researchers will interview healthcare providers and mothers to develop better support programs.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06582225Recruiting
Online CBT for OCD in children with autism
This study tests if internet-based cognitive behavioral therapy (CBT) can help children and teens with autism who also have OCD. Treatment is delivered online with parent support, making it easier to access care at home.
Lund, Skåne CountyAges 7–17 - NCT06575751RecruitingPhase 2
Study of cannabidiol and cannabis concentrate users
This study looks at how cannabidiol (a compound in cannabis) affects people who regularly use strong cannabis concentrates like wax, shatter, or oil. It may help understand if using CBD can change how cannabis affects the body or help with cannabis use disorder.
Aurora, ColoradoAges 25–60 - NCT05563363Recruiting
Home-based treatment for severe addiction problems
This trial tests a home-based treatment approach for adults with severe substance use problems. It may help you and your care team manage addiction with structured support while you stay at home.
GenevaAges 18 years+ - NCT06531980Recruiting
Digital app for teens with mild to moderate anxiety
This trial tests a digital app to help teens with mild to moderate anxiety. If you are 13–16, live in Bergen, and feel anxious often, this app might help you manage your worries and get back to doing things you enjoy.
Bergen, VestlandAges 13–16 - NCT04807530Recruiting
MRI brain study for people with schizophrenia symptoms
This study uses brain scans to look at how a specific brain area works in schizophrenia. If you qualify, it may help researchers better understand the brain changes linked to symptoms.
San Francisco, CaliforniaAges 18–64 - NCT04962087Recruiting
Online app treatment for long-lasting trouble sleeping
This study tests whether an app-based program can help adults with chronic insomnia (ongoing sleep problems). You may be able to use the program at home if you meet the symptom, safety, and schedule requirements.
Halifax, Nova ScotiaAges 18 years+ - NCT06552741Recruiting
Screening for substance and alcohol use studies
This study screens people with or without past or current substance or alcohol use problems. It helps the researchers see if you might qualify for other studies at the NIDA research center.
Baltimore, MarylandAges 18–99 - NCT06566170Recruiting
Donanemab for early Alzheimer's: a real-world study
This study compares donanemab plus usual care to usual care alone for people with early Alzheimer's symptoms, to see how well donanemab works in everyday life. You may be able to join if you have early memory or thinking problems and have a brain scan or blood test showing Alzheimer's-related changes.
Huntsville, AlabamaAges 60 years+ - NCT06559306RecruitingPhase 3
Seltorexant for depression with insomnia symptoms
This trial tests if adding seltorexant to your current antidepressant can improve depression and sleep problems. It is for people with major depressive disorder who still have symptoms, especially insomnia, despite trying at least one antidepressant.
Birmingham, AlabamaAges 18–74 - NCT06563895RecruitingPhase 3
Testing acoramidis to prevent ATTR amyloidosis in gene carriers
This trial tests a daily pill called acoramidis to see if it can prevent ATTR amyloidosis in people who carry a gene mutation but have no symptoms yet. It aims to stop the disease before it starts.
La Jolla, CaliforniaAges 18–75 - NCT06565416Recruiting
Pain & opioid treatment in Native communities
This study is testing better ways to treat pain and opioid use in Native American communities. It may help if you have chronic pain or struggle with opioids.
Arcata, CaliforniaAges 18 years+ - NCT06563466Recruiting
Pegasus: Better treatment for emotional instability
This study tests a new way to treat emotionally unstable personality disorder (also called borderline personality disorder) by including family or close friends in therapy. It aims to see if this approach improves how patients feel and function.
CopenhagenAges 18 years+ - NCT06566235Recruiting
Testing DBT therapy for teens with emotional issues in Taiwan
This trial is testing a type of talk therapy called Dialectical Behavior Therapy (DBT), adapted for teenagers in Taiwan who struggle with strong emotions like sadness, worry, or hyperactivity. The study will see if this culturally-adjusted therapy helps teens feel better and manage their emotions.
TaipeiAges 12–18
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.