Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06559774Recruiting
Strong Man program for American Indian men with substance use
This study tests a program called Strong Man, which is designed to help American Indian men who have used alcohol or drugs. The program aims to support their health and well-being. If you join, you will take part in sessions and assessments to see if the program helps.
Chinle, ArizonaAges 18 years+ - NCT06562608RecruitingPhase 4
Reducing Anticholinergic Medications in Schizophrenia
This trial is testing whether it is safe to slowly reduce or stop anticholinergic medications (benztropine or trihexyphenidyl) in people with schizophrenia. It aims to see if stopping these drugs can help with thinking and memory without causing worsening movement problems.
Pittsburgh, PennsylvaniaAges 40–70 - NCT06552286Recruiting
Study of STRW-T program for autistic teens in 11th and 12th grade
This trial tests the STRW-T program to help autistic high school students improve daily living skills. It is designed for teens who are in their last two years of high school or deferring graduation.
Carrboro, North CarolinaAges 15–21 - NCT06562153Recruiting
fMRI-guided TMS for depression
This trial tests whether combining fMRI brain scans with TMS (a non-invasive brain stimulation) can help treat depression more effectively. It is for adults with major depressive disorder who can safely undergo MRI.
Charleston, South CarolinaAges 18–65 - NCT06559995RecruitingPhase 2/Phase 3
Ketone drink for alcohol withdrawal
This study tests whether a special ketone drink can ease alcohol withdrawal and help your brain heal. If you have been drinking heavily for at least 3 years and are having withdrawal symptoms now, this might be an option for you.
Philadelphia, PennsylvaniaAges 18–65 - NCT06566664Enrolling by invitation
Peripheral neurostimulation for improving nerve block placement in upper limb surgery
This study looks at using peripheral neurostimulation to improve the placement of nerve blocks for upper limb surgery. It may help you get better pain control during and after your operation.
Stanford, CaliforniaAges 18 years+ - NCT06551090Recruiting
Anxiety and memory study for temporal lobe epilepsy patients
This research study looks at how anxiety and memory work in people with temporal lobe epilepsy. It uses brain recordings to better understand these conditions, which might lead to better treatments in the future.
New York, New YorkAges 18–55 - NCT06566235Recruiting
Testing DBT therapy for teens with emotional issues in Taiwan
This trial is testing a type of talk therapy called Dialectical Behavior Therapy (DBT), adapted for teenagers in Taiwan who struggle with strong emotions like sadness, worry, or hyperactivity. The study will see if this culturally-adjusted therapy helps teens feel better and manage their emotions.
TaipeiAges 12–18 - NCT06563310Recruiting
Brain Training for Anxiety Using Neurofeedback
This study tests whether a brain-training technique called neurofeedback can help people with certain anxiety disorders learn to change how they think about upsetting situations. Participants will do thinking exercises while an MRI machine measures their brain activity, which helps them see if they are using the right coping strategies.
Ann Arbor, MichiganAges 18–24 - NCT06565416Recruiting
Pain & opioid treatment in Native communities
This study is testing better ways to treat pain and opioid use in Native American communities. It may help if you have chronic pain or struggle with opioids.
Arcata, CaliforniaAges 18 years+ - NCT06563466Recruiting
Pegasus: Better treatment for emotional instability
This study tests a new way to treat emotionally unstable personality disorder (also called borderline personality disorder) by including family or close friends in therapy. It aims to see if this approach improves how patients feel and function.
CopenhagenAges 18 years+ - NCT06555406Recruiting
Healthy lifestyle study for bipolar disorder with sleep issues
This study tests a healthy lifestyle program for people with bipolar disorder who have sleep or schedule problems. It aims to see if changing daily habits can help improve mood and sleep.
Berkeley, CaliforniaAges 18–65 - NCT06560255RecruitingPhase 3
Fish oil in pregnancy to prevent childhood asthma
This study tests if taking fish oil during pregnancy can help lower the risk of childhood asthma. If you have low omega-3 levels, you may be randomly assigned to receive fish oil or a placebo.
Gentofte MunicipalityAges 18–45 - NCT06565663Enrolling by invitation
Decision aid for gender-affirming surgeries
This study tests an online decision tool for people considering metoidioplasty or phalloplasty. The tool helps patients compare surgical options to make informed choices.
Hanover, New HampshireAges 18 years+ - NCT06551246RecruitingPhase 3
Medicines for daytime wetting in children
This study tests two medicines (solifenacin and mirabegron) alone and together to see which works best for children with daytime wetting. It is for children ages 5 to 14 who still have accidents after trying non-drug treatments.
Aalborg, AalborgAges 5–14 - NCT06557005Recruiting
Helping new mothers with chronic conditions get primary care
This study helps new mothers with chronic health conditions transition smoothly from pregnancy care to regular primary care. If you have high blood pressure, diabetes, severe obesity, depression, or anxiety, you may be able to join a program that coordinates your care after childbirth.
Boston, MassachusettsAges 18 years+ - NCT06560749Recruiting
Exercise to help thinking in bipolar disorder
This study tests whether a regular exercise program can help improve thinking and memory problems that often come with bipolar disorder. You must have stable mood and no recent changes to your medications.
São Paulo, São PauloAges 18–60 - NCT06551987Recruiting
Insomnia treatment for military members with mild brain injury
This study tests a behavioral insomnia therapy for active-duty service members who have had a mild traumatic brain injury and continue to have sleep problems and other symptoms. It aims to help improve sleep and recovery.
Fort Cavazos, TexasAges 18–45 - NCT06566612Recruiting
Understanding decisions in anorexia and bulimia through MRI
This study uses brain scans to understand how people with eating disorders make decisions and learn. It may help find better treatments for anorexia and bulimia.
La Jolla, CaliforniaAges 18–39 - NCT06551038Recruiting
Suicide prevention program for at-risk teens
This study tests a new program to help prevent suicide in teens and young adults who face extra challenges. It is designed for those who are already struggling with mental health, school, detention, or other tough life situations.
Geneva, Canton of GenevaAges 14–25 - NCT06558201Enrolling by invitation
Open-label extension for completers of earlier study
This trial is for people who finished a 12-week study (NCT06221852) and still meet its original requirements. It offers continued access to the study treatment.
Belmont, MassachusettsAges 18–45 - NCT06556602Recruiting
Study to improve access to methadone treatment
This trial tests a new way to help people get methadone treatment by working with staff at opioid treatment programs. It might lead to better access for patients.
Tucson, ArizonaAges 18 years+ - NCT06560554Enrolling by invitation
Fermented diet for long COVID microbiome health
This study tests whether eating fermented foods (like yogurt, kimchi, or sauerkraut) can improve gut health and ease symptoms in people with long COVID. You'll log your food on your phone and follow a fermented diet for a period of time.
Rochester, MinnesotaAges 18 years+ - NCT03262259Recruiting
Testing a global smart drinking goals program
This study looks at a “smart drinking goals” program for teens and adults. If it helps, it could guide safer drinking choices and goal-setting in everyday life.
Calverton, MarylandAges 12 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.