Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT06511752RecruitingEarly Phase 1
Support group for Spanish/English speakers with progressive aphasia
This trial tests a support group program for people with progressive aphasia (a language disorder that gets worse over time) and their caregivers. The groups meet online to share experiences and learn together.
Austin, TexasAges 18 years+ - NCT06506162Recruiting
Oral nicotine pouch study for young adult vapers
This study looks at how young adults who vape react to oral nicotine pouches (like Zyn). It tests whether these products might be appealing or lead to misuse. You must be 21–25, an exclusive vaper, and never have used nicotine pouches before.
Los Angeles, CaliforniaAges 21–25 - NCT06512662Recruiting
Support program for ENT cancer patients in a day hospital
This trial offers a support program for patients undergoing surgery for head and neck cancer. The goal is to help with recovery and well-being.
BrestAges 18 years+ - NCT06500637RecruitingPhase 2
TB006 for autism in adults
This study tests an experimental medication called TB006 for adults with autism. It aims to see if it can help reduce symptoms. Participants must be 18–35, have moderate-to-severe autism, and have a caregiver who can join them.
Phoenix, ArizonaAges 18–35 - NCT06511544Recruiting
Brain stimulation for treatment-resistant depression with rumination
This study tests whether a specific form of brain stimulation (called rTMS) can help people with treatment-resistant depression by targeting brain circuits linked to rumination (repetitive negative thinking). If you have tried at least one antidepressant without success and do not have other major mental health conditions, this trial may be worth exploring with your doctor.
Indianapolis, IndianaAges 18–70 - NCT06511011RecruitingPhase 2
Chinese Herbal Medicine for Chronic Insomnia
This trial tests a Chinese medicine treatment for people with long-term insomnia that is caused by a specific imbalance (Yin deficiency with internal heat). It aims to see if the herbal formula can improve sleep quality and daily function.
ShatinAges 18–65 - NCT06496425Recruiting
Exercise for protecting memory in older adults
This study tests whether a 12-month exercise program can help protect memory and thinking skills in older adults who have noticed changes in their memory. You would be asked to exercise at home and attend some group classes.
Atlanta, GeorgiaAges 65 years+ - NCT06501495Recruiting
Brain waves and memory in aging and Alzheimer's
This study looks at how brain waves (EEG) change during normal aging and early Alzheimer's disease. It compares three groups: people with early-stage Alzheimer's, healthy older adults, and healthy young adults. The goal is to understand how memory and thinking problems relate to slow brain wave activity.
ParisAges 18–85 - NCT06501781Recruiting
PUSH: Helping People with HIV and Substance Use
This study tests if a program that encourages positive activities (behavioral activation) can help people with HIV or on PrEP who also use substances improve their health. It focuses on those receiving long-acting injectable medications for HIV prevention or treatment.
Washington D.C., District of ColumbiaAges 18–88 - NCT06495684Recruiting
A brain stimulation study for adults with autism
This trial tests whether mild brain stimulation (transcranial direct current stimulation or tDCS) over multiple sessions can improve thinking, behavior, and brain activity in adults with autism. It may help researchers learn if this safe, noninvasive treatment can support better daily functioning.
Albuquerque, New MexicoAges 18–35 - NCT06512194RecruitingPhase 2
Psilocybin for depression study
This trial tests whether psilocybin can help people with major depression who are currently having a depressive episode. It aims to understand how the treatment works and if it is safe and effective.
Edwards, ColoradoAges 18–70 - NCT04627415Recruiting
Early support program for ADHD symptoms in preschool children
This trial tests an early intervention program for young children (about ages 3 to 5) with clinically significant attention and behavior symptoms. It may help by targeting ADHD-related difficulties seen at home and school.
Bethlehem, PennsylvaniaAges 3–5 - NCT06487533Recruiting
Sensing opioid withdrawal and cravings with wearable sensors
This study uses wearable sensors to track physical signs of opioid withdrawal and cravings over 14 days. It aims to better understand these symptoms in people currently taking or planning to start medication for opioid use disorder.
Center City, MinnesotaAges 18–50 - NCT06480383RecruitingPhase 2
Adding an experimental pill to current anxiety medication
This study tests an experimental medication (ITI-1284) added to your current anxiety treatment to see if it improves symptoms. It's for adults with generalized anxiety disorder (GAD) who haven't gotten enough relief from their current medicine.
Glendale, CaliforniaAges Any age - NCT06477796Recruiting
Improving sleep in veterans with TBI and sleep problems
This study tests a new way to help Veterans with both a traumatic brain injury (TBI) and sleep problems get better rest. If you are a Veteran with sleep trouble and a history of TBI, this program may help improve your sleep without needing extra medication.
Portland, OregonAges 18–89 - NCT06484088RecruitingEarly Phase 1
Brain scanning study of frustration in healthy adults
This study looks at how the brain handles frustration in healthy adults using a special brain scanner called magnetoencephalography (MEG). It may help researchers understand normal brain responses to frustration.
Bethesda, MarylandAges 18–55 - NCT05590637RecruitingPhase 4
Compare antipsychotic medicines for Parkinson or Lewy body psychosis
This study compares two medicines—quetiapine and pimavanserin—in people with psychosis caused by Parkinson’s disease or Lewy body dementia, looking at how they work over time. You might join if you are starting an antipsychotic for the first time and your clinician can safely manage either option.
San Antonio, TexasAges Any age - NCT06312956Recruiting
Sleep Apnea and Ventilotherapy: A Study Before and After Treatment
This trial studies how sleep apnea affects the body and brain before and after starting treatment with a breathing device (ventilotherapy). It aims to understand the benefits of early treatment for people with obstructive sleep apnea.
Piancavallo, VCOAges 20–60 - NCT06490315Enrolling by invitation
Studying OkeyMind for social anxiety in young people
This trial tests if a smartphone program called OkeyMind helps reduce social anxiety in young people aged 15-24. It also looks at whether the program is worth the cost.
Hong Kong, Hong KongAges 15–24 - NCT06493708Recruiting
EMDR Therapy for Borderline Personality Disorder
This study tests whether Eye Movement Desensitization and Reprocessing (EMDR) therapy can help people with Borderline Personality Disorder (BPD). EMDR is a type of talk therapy often used for trauma, and this trial wants to see if it can improve BPD symptoms.
Brescia, BresciaAges 18–65 - NCT06485934Recruiting
A new questionnaire to measure fear of arm movement
This study is for people with arm or shoulder problems who are afraid of moving because they worry about pain or injury. Researchers want to test a new questionnaire that measures this fear, so they can better understand and help patients like you.
IstanbulAges 18–65 - NCT06480019Recruiting
Group talk therapy for depression in young adults
This study tests if a group therapy program led by non-professionals can help reduce depressive symptoms in young adults aged 18-24 who live, work, or study in Porto Alegre, Brazil. You may benefit if you have mild to moderate depression but no risk of suicide.
Porto Alegre, Rio Grande do SulAges 18–24 - NCT06481878Recruiting
Testing a stool test for Alzheimer’s markers
This study checks if Alzheimer’s-related proteins (amyloid and tau) can be found in stool samples. It may help develop a simple, non-invasive way to detect Alzheimer’s disease.
GrenobleAges 40 years+ - NCT06493773Recruiting
Alcohol help for new liver disease diagnosis
This trial tests a program to help people recently diagnosed with alcohol-related liver disease cut back on drinking. If you qualify, you may get support to improve your liver health.
Køge, KøgeAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.