Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06502964RecruitingPhase 2
ALTO-101 study for schizophrenia cognitive symptoms
This study tests an experimental medication called ALTO-101 for people with schizophrenia who also have cognitive impairment (memory or thinking problems). It aims to see if the drug can improve these symptoms while you continue your current antipsychotic treatment.
Garden Grove, CaliforniaAges 21–55 - NCT06512324Enrolling by invitation
TMS with remote viewing for depression and anxiety
This trial tests whether adding 'remote viewing' (a technique where a person tries to perceive a distant target) to standard TMS brain stimulation can improve depression and anxiety symptoms. It is for people already getting TMS and who can attend weekly visits.
Encinitas, CaliforniaAges 12 years+ - NCT06504290RecruitingPhase 1
Safety study of VV119 for healthy adults and people with schizophrenia
This trial tests if a new drug called VV119 is safe and how it works in the body. It is for healthy volunteers and for people who have had schizophrenia for at least a year and are currently having worsening symptoms.
Beijing, Beijing MunicipalityAges 18–65 - NCT06506344Recruiting
Suicide prevention screening for people leaving jail
This study looks at a new way to connect people leaving jail with suicide prevention services. It tests whether better coordination between health systems and jails can help reduce suicide risk.
Detroit, MichiganAges 18 years+ - NCT06506162Recruiting
Oral nicotine pouch study for young adult vapers
This study looks at how young adults who vape react to oral nicotine pouches (like Zyn). It tests whether these products might be appealing or lead to misuse. You must be 21–25, an exclusive vaper, and never have used nicotine pouches before.
Los Angeles, CaliforniaAges 21–25 - NCT06497894RecruitingPhase 4
Hormone therapy for sleep in late menopause
This trial tests whether hormone replacement therapy (HRT) can improve sleep for women in late menopause who have insomnia. If you are in late menopause and struggle with poor sleep, this study may offer a treatment option.
BernAges 45–69 - NCT06499740Recruiting
Supporting teens with suicidal thoughts in primary care
This study tests a short, supportive conversation for teens with suicidal thoughts that happens in their regular doctor's office. It aims to help teens and their families get the right care without needing a hospital stay.
Centralia, WashingtonAges 10 years+ - NCT06496425Recruiting
Exercise for protecting memory in older adults
This study tests whether a 12-month exercise program can help protect memory and thinking skills in older adults who have noticed changes in their memory. You would be asked to exercise at home and attend some group classes.
Atlanta, GeorgiaAges 65 years+ - NCT06511011RecruitingPhase 2
Chinese Herbal Medicine for Chronic Insomnia
This trial tests a Chinese medicine treatment for people with long-term insomnia that is caused by a specific imbalance (Yin deficiency with internal heat). It aims to see if the herbal formula can improve sleep quality and daily function.
ShatinAges 18–65 - NCT06512662Recruiting
Support program for ENT cancer patients in a day hospital
This trial offers a support program for patients undergoing surgery for head and neck cancer. The goal is to help with recovery and well-being.
BrestAges 18 years+ - NCT06511752RecruitingEarly Phase 1
Support group for Spanish/English speakers with progressive aphasia
This trial tests a support group program for people with progressive aphasia (a language disorder that gets worse over time) and their caregivers. The groups meet online to share experiences and learn together.
Austin, TexasAges 18 years+ - NCT06501495Recruiting
Brain waves and memory in aging and Alzheimer's
This study looks at how brain waves (EEG) change during normal aging and early Alzheimer's disease. It compares three groups: people with early-stage Alzheimer's, healthy older adults, and healthy young adults. The goal is to understand how memory and thinking problems relate to slow brain wave activity.
ParisAges 18–85 - NCT06501781Recruiting
PUSH: Helping People with HIV and Substance Use
This study tests if a program that encourages positive activities (behavioral activation) can help people with HIV or on PrEP who also use substances improve their health. It focuses on those receiving long-acting injectable medications for HIV prevention or treatment.
Washington D.C., District of ColumbiaAges 18–88 - NCT06501677Recruiting
Web program for couples concerned about drinking
This trial tests a web-based program for couples where one partner is concerned about their drinking. You and your partner will use a smartphone app to share daily feelings and drinking habits, with the goal of reducing risky drinking.
Portland, OregonAges 18 years+ - NCT06500117Recruiting
Mindfulness app for quitting smoking
This trial tests a digital mindfulness program on your smartphone to help you quit smoking and stay smoke-free. It's for adults who have a smoking-related health problem and are motivated to stop.
DijonAges 18 years+ - NCT06496646Recruiting
Depression and Antidepressant Adherence in Primary Care
This study tests whether a special electronic pill bottle that reminds you to take your antidepressant helps people stay on their medication. It is for adults with major depression who are starting a new antidepressant prescribed by their primary care doctor.
Philadelphia, PennsylvaniaAges 21–64 - NCT06497920Recruiting
Brain stimulation for motor skills in autistic adults
This trial tests whether a type of brain stimulation called rTMS can improve motor skills (like coordination and movement) in autistic adults. If you have autism and notice challenges with motor function, this study may help.
Toronto, OntarioAges 18–40 - NCT06497101Recruiting
A therapy with support for adults with anorexia nervosa
This study tests a new type of therapy called Temperament Based Therapy with Support (TBT-S) for adults with anorexia nervosa. It involves bringing a support person to sessions to help with recovery.
OsloAges 18 years+ - NCT06511544Recruiting
Brain stimulation for treatment-resistant depression with rumination
This study tests whether a specific form of brain stimulation (called rTMS) can help people with treatment-resistant depression by targeting brain circuits linked to rumination (repetitive negative thinking). If you have tried at least one antidepressant without success and do not have other major mental health conditions, this trial may be worth exploring with your doctor.
Indianapolis, IndianaAges 18–70 - NCT06507254Recruiting
Polyphenols and brain health in aging
This study tests whether eating more polyphenols (natural compounds in plants) can protect brain health in people at higher risk for Alzheimer's disease, especially if they currently eat a typical Western diet. Participants will be followed over time to see if changes in diet affect thinking and memory.
Los Angeles, CaliforniaAges 50 years+ - NCT06513156Recruiting
Care support for hospitalized patients with drug-related infections
This study is for people who are in the hospital with a serious infection caused by injection drug use. It aims to provide better care and support while you are in the hospital and after you leave.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06495684Recruiting
A brain stimulation study for adults with autism
This trial tests whether mild brain stimulation (transcranial direct current stimulation or tDCS) over multiple sessions can improve thinking, behavior, and brain activity in adults with autism. It may help researchers learn if this safe, noninvasive treatment can support better daily functioning.
Albuquerque, New MexicoAges 18–35 - NCT06500637RecruitingPhase 2
TB006 for autism in adults
This study tests an experimental medication called TB006 for adults with autism. It aims to see if it can help reduce symptoms. Participants must be 18–35, have moderate-to-severe autism, and have a caregiver who can join them.
Phoenix, ArizonaAges 18–35 - NCT06512194RecruitingPhase 2
Psilocybin for depression study
This trial tests whether psilocybin can help people with major depression who are currently having a depressive episode. It aims to understand how the treatment works and if it is safe and effective.
Edwards, ColoradoAges 18–70
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.