Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT06399952Recruiting
Natural history study for Baker Gordon syndrome
This study follows people with Baker Gordon syndrome over time to better understand the condition. Participants and their caregivers share medical records and complete tests and questionnaires.
Columbia, MissouriAges birth–99 years - NCT06413979Recruiting
Family support program for teens with substance use and mood or anxiety issues
This trial offers a family support program for teens with both substance use and internalizing problems like depression or anxiety. The goal is to help you and your caregiver work together to manage symptoms and improve well-being.
Jacksonville, FloridaAges 13–21 - NCT05226624Recruiting
Improving care for babies born with opioid withdrawal
This program helps participating hospitals improve care for newborns who may go through opioid withdrawal (also called neonatal abstinence syndrome). It mainly aims to make mother-baby support and treatment plans work better after delivery.
Edmonton, AlbertaAges Any age - NCT04979338RecruitingPhase 3
Opioid-sparing pain control for gender-affirming surgery
This Phase 3 study tests ways to manage pain during and after gender-affirming surgery while using less opioid medicine. It may help improve comfort after surgery and reduce opioid-related side effects.
Los Angeles, CaliforniaAges 18 years+ - NCT05794061Recruiting
Testing new ways to assess brain and behavior health
This study is developing and checking better tests to understand neurological (brain-related) and psychiatric (mental health) conditions. If you have a diagnosed brain or mental health condition—or you’re being considered as a healthy person—your results will help researchers see how well these assessments work.
Milan, LombardyAges 20–100 - NCT06395558Recruiting
Online support program for cardiac arrest survivors
This trial tests if an internet-based program helps people recover after a cardiac arrest. You may qualify if you were discharged from the hospital with good brain function and can use the web.
Bologna, BolognaAges 18–80 - NCT04560517Recruiting
Study remission factors in anorexia nervosa
This study looks for factors that may help people with anorexia nervosa reach remission (lessening or recovery of symptoms). If you join, your team may assess your health and brain signals to understand what supports recovery.
ParisAges 18–65 - NCT05299749Recruiting
Brain training using real-time fMRI for hearing voices in schizophrenia
This trial tests whether real-time brain imaging “neurofeedback” can help people with schizophrenia who have ongoing auditory hallucinations (hearing voices) that haven’t improved with medications. If you qualify, you may complete brain-scanning sessions where you practice changing brain activity while being monitored.
Brockton, MassachusettsAges 18–55 - NCT06381180RecruitingPhase 1/Phase 2
Cannabis for Veterans with PTSD
This study is testing whether cannabis can help veterans with PTSD feel better. It is for veterans who have used cannabis before and currently have PTSD symptoms.
Detroit, MichiganAges 19–69 - NCT06384196Recruiting
Virtual-reality therapy for anxiety and depression in young people
This study tests a new virtual-reality therapy for young people struggling with anxiety or depression. It aims to help you feel better by addressing both conditions together.
BadalonaAges 16–29 - NCT06383806Recruiting
Reducing nightmares in adults with narcolepsy
This study tests a new behavioral treatment to reduce nightmares in adults with narcolepsy. It aims to help you sleep better and feel more rested.
Salt Lake City, UtahAges 18 years+ - NCT06386497Recruiting
Bed for better sleep in Parkinson's disease
This study tests a special bed (Somnomat Casa) to help improve sleep in people with Parkinson's disease. It looks at whether the bed is comfortable and acceptable to use.
BernAges 18–85 - NCT06379984RecruitingPhase 2
Quick-start buprenorphine for opioid addiction with fentanyl use
This trial tests a way to quickly start buprenorphine (a medication for opioid addiction) in an outpatient clinic for people who use fentanyl. It aims to make starting treatment easier and faster, without needing to go through full withdrawal first.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06397469Recruiting
Digital program for attention and wellbeing in older adults
This study tests a digital program designed to help improve attention and overall wellbeing in older adults. You can take part from home using your own smartphone or tablet.
San Francisco, CaliforniaAges 60–99 - NCT06386029Recruiting
Bedtime routine study for children with autism
This study tests a new bedtime routine designed to help children with autism who are very sensitive to sensory input and have trouble settling down at night. It may help your child fall asleep more easily.
Pittsburgh, PennsylvaniaAges 6–10 - NCT06383221Enrolling by invitation
Psychological and prenatal support for depression or anxiety in pregnancy
This trial tests a step-by-step program that combines psychological support and prenatal care to help pregnant women manage depression or anxiety. It is designed for women who have screened positive for these symptoms but are not yet receiving treatment.
Ma’anshanAges 18 years+ - NCT06391684Recruiting
Brain flexibility in autistic and non-autistic adults
This study looks at how the brain predicts and adapts in autistic and non-autistic people. Participants will have MRI scans and do simple tasks to help researchers understand flexibility in thinking.
GrenobleAges 18–50 - NCT06395389Recruiting
A brief program to help young adults cut back on cannabis
This trial tests a short, one-time program designed to help people ages 18-25 who use cannabis frequently (at least 20 days per month) reduce their use. It may be a good fit if you're not already in treatment and are thinking about making a change.
Charleston, South CarolinaAges 18–25 - NCT06393439Recruiting
Virtual reality for functional movement disorder
This study tests whether virtual reality can help people with functional or essential tremor. You may join if you have one of these tremor types or are a healthy volunteer.
GrazAges 18–65 - NCT06399263RecruitingPhase 2
Psilocybin for anorexia in young adults
This trial tests whether a single dose of psilocybin (a psychedelic substance) can help treat anorexia nervosa in young adults. It involves taking the medication in a safe, supervised setting and participating in therapy sessions with a support person.
San Francisco, CaliforniaAges 18–25 - NCT06387290RecruitingPhase 3
Mindfulness and pain management for chronic pain on opioids
This study tests whether adding mindfulness training to standard pain management visits can help people with chronic pain who are taking long-term opioids. It aims to improve pain relief and reduce opioid-related risks.
La Jolla, CaliforniaAges 18 years+ - NCT06396312Recruiting
Predicting lithium response in difficult depression
This study looks at how to predict which people with hard-to-treat depression will benefit from adding lithium to their antidepressant. If you have treatment-resistant depression and are considering lithium, this trial may help find the best treatment for you.
Munich, BavariaAges 18 years+ - NCT06384209Recruiting
Friendship Bench Plus for Depression
This study tests whether a structured talk therapy program called the Friendship Bench can help adults with moderate to severe depression. You will have conversations with trained lay counselors who guide you through problem-solving techniques.
HarareAges 18 years+ - NCT06379074Recruiting
Sleep in pregnancy and postpartum mental health
This study looks at how poor sleep during pregnancy might affect stress and mental health after childbirth. It aims to help new mothers by understanding these links.
Bologna, BolognaAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.