Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT06397469Recruiting
Digital program for attention and wellbeing in older adults
This study tests a digital program designed to help improve attention and overall wellbeing in older adults. You can take part from home using your own smartphone or tablet.
San Francisco, CaliforniaAges 60–99 - NCT06396312Recruiting
Predicting lithium response in difficult depression
This study looks at how to predict which people with hard-to-treat depression will benefit from adding lithium to their antidepressant. If you have treatment-resistant depression and are considering lithium, this trial may help find the best treatment for you.
Munich, BavariaAges 18 years+ - NCT06384209Recruiting
Friendship Bench Plus for Depression
This study tests whether a structured talk therapy program called the Friendship Bench can help adults with moderate to severe depression. You will have conversations with trained lay counselors who guide you through problem-solving techniques.
HarareAges 18 years+ - NCT06389175Enrolling by invitation
Non-invasive ear stimulation for depression
This study uses a gentle, non-invasive device that stimulates the vagus nerve in your ear to see if it can improve how your stomach and brain communicate, which may help with depression symptoms.
BonnAges 18–55 - NCT06387290RecruitingPhase 3
Mindfulness and pain management for chronic pain on opioids
This study tests whether adding mindfulness training to standard pain management visits can help people with chronic pain who are taking long-term opioids. It aims to improve pain relief and reduce opioid-related risks.
La Jolla, CaliforniaAges 18 years+ - NCT06395467Recruiting
Integrated treatment for teens with substance use disorder
This trial tests a treatment program for teens and young adults with substance use disorders. It includes family members and is designed to support recovery and personal growth.
Farmington, ConnecticutAges 14–21 - NCT05738174Recruiting
High-dose brain stimulation to help treat alcohol addiction
This trial studies a type of noninvasive brain stimulation to reduce alcohol dependence and help people drink less or stop. You may be offered an accelerated treatment schedule, with regular check-ins and questionnaires to track progress.
RegensburgAges 18–65 - NCT05681767Recruiting
Lifestyle coaching to support depression care in primary clinics
This trial studies whether motivational, multi-part lifestyle coaching can help adults with depression when they start treatment through a regular primary care clinic. If you’re eligible, the program may add supportive skills to help improve mood alongside usual care.
KuopioAges 18 years+ - NCT05892952Recruiting
Scottish long-term study of aging and thinking
This study follows adults aged 50 and older over time to understand how thinking and memory change. You may help researchers learn what influences healthy aging and cognitive health.
Edinburgh, LothianAges 50–120 - NCT06364488Recruiting
App for monitoring depression and anxiety in pregnancy
This trial tests a mobile app called TrueBlue to help monitor depression and anxiety in new and expecting mothers. If you are pregnant or recently gave birth, the study will see if the app can make tracking your moods easier and connect you with care.
Nottingham, NottinghamshireAges 18 years+ - NCT06027632Recruiting
Brain training at home to help with chemo brain after breast cancer treatment
This study tests a supervised computer-based mental exercise program to help reduce memory and thinking problems after chemotherapy. It is for people who finished chemo for early-stage breast cancer and still have bothersome mental fogginess.
BordeauxAges 1.5 years+ - NCT06378541Recruiting
Smartphone app for suicide prevention in veterans
This study tests if a smartphone app can help veterans who are hospitalized after a suicidal crisis. The app is designed to support mental health and prevent future crises.
Ann Arbor, MichiganAges 18 years+ - NCT06375083RecruitingPhase 2
Computer therapy for suicide prevention and depression in Veterans
This trial tests two different computer-based therapy programs for Veterans: one for preventing suicide and one for treating depression. Both programs are designed to be done at home on your computer or tablet.
Aurora, ColoradoAges 18–65 - NCT06362707RecruitingPhase 2
Fasudil trial for early Alzheimer's disease
This trial tests a medication called fasudil to see if it can help people with early Alzheimer's disease. It is for people who have early symptoms (mild cognitive impairment or mild dementia) and have biomarker evidence of Alzheimer's in their brain.
Tromsø, NordlandAges 50–100 - NCT06372964RecruitingPhase 3
Lumateperone for pediatric bipolar depression
This study tests a new medication called lumateperone for treating depression in children and teens with bipolar disorder. It aims to see if this drug can help improve mood and daily functioning.
Dothan, AlabamaAges 10–17 - NCT06366464RecruitingPhase 3
Study of a drug for sleepiness in Prader-Willi syndrome
This trial tests a medication called pitolisant to see if it helps reduce excessive daytime sleepiness in people with Prader-Willi syndrome. You or your loved one may be able to join if they have a confirmed diagnosis and a caregiver who can regularly help with study tasks.
Los Angeles, CaliforniaAges 6 years+ - NCT06365723Recruiting
Walking in Nature vs. City for Prediabetes
This study compares walking in natural green spaces (like parks) versus walking in built environments (like city streets) for adults with prediabetes. You will be asked to walk three times a week for 30 minutes for 4 weeks in each setting, and researchers will see how your body responds.
Lake Forest, IllinoisAges 25–64 - NCT06367348Recruiting
Couples program to cut alcohol use in Malawi
This study tests a program that helps couples in Malawi reduce alcohol use and strengthen their relationship. It is for people living with HIV who are in a long-term relationship and ready to work together with their partner.
ZombaAges 18 years+ - NCT06378281Recruiting
Improving informed consent for prison research
This study tests a new way of explaining research to people in prison to make sure they understand what they are agreeing to. Participating could help improve how research is done in prisons and make consent clearer for everyone.
Geneva, Canton of GenevaAges 18–65 - NCT06375265Recruiting
Sleep improvement program for older surgery patients
This trial tests a digital sleep improvement program for older adults who are about to have knee or hip replacement surgery. It aims to help you sleep better before and after surgery, which may improve your brain health and recovery.
Boston, MassachusettsAges 65 years+ - NCT06374277Recruiting
Pharmacy Coaching to Help After Hospital Stay
This study tests a program where a pharmacist helps you manage your medications after you leave the hospital. It is for people with long-term health conditions who want to stay on track with their medicines.
Knoxville, TennesseeAges 18 years+ - NCT06376760Recruiting
Anesthetic dose changes for insomnia patients during endoscopy
This study looks at how insomnia affects the amount of anesthesia needed during a digestive endoscopy. It compares people with insomnia to those with normal sleep to see if dosage adjustments are needed.
Beijing, Beijing MunicipalityAges 18–64 - NCT06378554Enrolling by invitation
Cereset study for stress and performance in nurses
This study tests whether a new brain-calming technique called Cereset can help healthcare workers on the Orthopedic Trauma Unit feel less stressed and perform better. You would sit in a chair and listen to gentle sounds that help your brain relax.
Winston-Salem, North CarolinaAges 18–100 - NCT06377033Recruiting
Using health records to advance genomic medicine for all
This study uses electronic health records to learn how to improve genomic medicine across a diverse health system. It may help make DNA-based healthcare more accessible and effective for people with certain conditions.
Philadelphia, PennsylvaniaAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.