Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT06323824RecruitingPhase 4
Methadone vs. buprenorphine for opioid use disorder treatment
This study compares two medications, methadone and buprenorphine, to see which helps people stay in treatment for opioid use disorder. You may be eligible if you are starting a new treatment episode.
Oakland, CaliforniaAges 18–99 - NCT06324318RecruitingPhase 2
Parenting program for American Indian families in cities
This study tests a parenting program for American Indian parents and their children aged 12-17 who live in cities. It aims to help families strengthen their connections and support healthy development.
Phoenix, ArizonaAges 12 years+ - NCT06330779Recruiting
Trauma-adapted yoga for teens with PTSD or ADHD
This trial tests if a special yoga program helps teenagers with PTSD or ADHD feel better. It is designed to be safe and supportive for their mental health.
GothenburgAges 12–18 - NCT06328127Recruiting
Positive psychology program for stem cell transplant survivors
This study tests a positive psychology program—simple exercises to help you feel better emotionally—for people who are about 3 months past a donor stem cell transplant. It's done over the phone, so you can join from home.
Tampa, FloridaAges 18 years+ - NCT06329453Recruiting
Gut immunity and brain health study
This study looks at how your gut's immune system relates to brain and nerve diseases. Researchers will collect samples during a colonoscopy to better understand connections between gut health and neurologic conditions like multiple sclerosis or Parkinson's disease.
North Haven, ConnecticutAges 18–99 - NCT06335407RecruitingPhase 1
Testing a new under-the-tongue med for alcohol use and trauma
This study tests a new sublingual (under-the-tongue) medication for people with alcohol use disorder who have also had a traumatic life event. It aims to see if the medication can help reduce drinking and related symptoms.
West Haven, ConnecticutAges 21–65 - NCT06335043Recruiting
Personalized medication matching for veterans with OSI
This trial tests whether using genetic information to guide medication choices can improve treatment for veterans with operational stress injuries (OSI). It aims to help find the right medication faster and with fewer side effects.
London, OntarioAges 18 years+ - NCT06324955Recruiting
Using words during mask anesthesia in children
This study looks at whether simple spoken words during the process of falling asleep with a breathing mask can help children ages 5–10 have a better experience. The goal is to make anesthesia induction less scary for kids.
Boston, MassachusettsAges 5–10 - NCT06330467Recruiting
Study of dissociative identity disorder in adults with childhood trauma
This study looks at how common dissociative identity disorder (a condition where a person may have two or more distinct identities) is in adults who experienced trauma as children. Participants will undergo a psychological evaluation to help researchers understand the link between childhood trauma and dissociative symptoms.
NancyAges 18 years+ - NCT06332963Recruiting
Trial on body image and internal body signals in anorexia
This study explores how the brain senses internal body signals linked to body image in anorexia. It may help develop better treatments by understanding these connections.
Tulsa, OklahomaAges 13–50 - NCT05833087Recruiting
Schema therapy for long-lasting, hard-to-treat depression
This study tests whether schema therapy can help people with chronic depression that hasn’t improved enough with standard antidepressant treatments. You’d be in a psychiatric clinic and be assessed for severity and diagnosis, then receive the therapy being studied.
Ballerup MunicipalityAges 18–65 - NCT04080440Recruiting
Checking readiness to remove the breathing tube after brain injury
This study looks at how to judge when it is safe to remove the breathing tube in people in the ICU after a brain injury. It may help improve timing and safety of extubation, when supported by a breathing trial and clinical stability.
AngersAges 18–75 - NCT04173416Recruiting
Support program for young adults in opioid recovery
This study tests a structured recovery support program for adults age 18–28 who have opioid use disorder. It may help by adding extra involvement and support while you receive common long-acting opioid treatment from a medical clinic.
Baltimore, MarylandAges 18–28 - NCT05838404Recruiting
Program to support mental health during early pregnancy
This study tests an intervention meant to improve mental health for people during pregnancy, starting in the first part of pregnancy. You might be able to join if you are already receiving prenatal care and speak English or Spanish.
New Orleans, LouisianaAges 18 years+ - NCT06037785Recruiting
Self-management support after an ICD shock
This study tests a self-management program to help people who have received a shock from their implantable cardioverter-defibrillator (ICD). The goal is to see if this program can improve recovery and well-being after a shock.
Seattle, WashingtonAges 18 years+ - NCT06303778Recruiting
Smartphone app with medications for heavy drinking
This study tests whether a smartphone app, when used alongside medications for alcohol use disorder, helps Veterans reduce heavy drinking. If you're a Veteran receiving care at the VA, this could be a way to get extra support for your drinking goals.
Phoenix, ArizonaAges 18–80 - NCT06309264Recruiting
Comparing ways to fit hearing aids for blast-exposed Veterans
This study compares two different ways of fitting hearing aids for Veterans who were exposed to blasts and now have hearing difficulties. The goal is to see which method works better for improving hearing and understanding speech.
Loma Linda, CaliforniaAges 18–60 - NCT06309329Enrolling by invitation
Strength at Home for Veteran Parents: A Study
This study tests a program called Strength at Home for veteran parents. It helps improve parenting and reduce stress for veterans with PTSD who have a child between 3 and 12 years old.
Temple, TexasAges 18 years+ - NCT06310434Enrolling by invitation
Understanding compassion in teens and young adults facing end-of-life
This study looks at how teenagers and young adults understand compassion and human connection when facing the end of life. It may help improve how schools and families support young people during difficult times.
Murcia, MUAges 12–23 - NCT06303986Enrolling by invitation
Observation study for newborns with or without NAS
This study is collecting information from two groups of newborns: those with Neonatal Abstinence Syndrome (NAS, caused by drug exposure before birth) and healthy newborns. The goal is to see if an automated system makes it easier to gather data without extra tests or procedures.
Albuquerque, New MexicoAges Up to 4 weeks - NCT06297590RecruitingPhase 1
First human study of a new Alzheimer's drug
This study tests an experimental drug (LY3954068) for people with early Alzheimer's disease. It aims to see if the drug is safe and may slow memory loss. You'll need a PET scan to measure tau protein in the brain and have a study partner who can help attend appointments.
Maitland, FloridaAges 50–85 - NCT06312189Enrolling by invitationPhase 3
Long-term safety study of valbenazine for Huntington's chorea in Canada
This study is for people in Canada who have already been taking valbenazine for Huntington's chorea in a previous study (NBI-98854-HD3006). It tests the long-term safety of the medicine and continues for up to 156 weeks.
Vancouver, British ColumbiaAges 18 years+ - NCT06298474Recruiting
BRAIN App for dementia support
This study is testing a new app (BRAIN App) designed to help people with dementia stay connected and engaged. Researchers want to see if the app can be useful for older adults who can still communicate and have not had a recent fast decline in health.
Winchester, MassachusettsAges 65 years+ - NCT06313918Recruiting
Exercise therapy for schizophrenia and bipolar disorder
This study tests whether an exercise program can help people with schizophrenia or bipolar disorder. It aims to see if physical activity improves mental health and overall well-being.
BergenAges 16 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.