Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,195 recruiting studies in this area right now.
By phase
- Not applicable6,798
- Phase 2512
- Phase 1258
- Phase 3245
- Phase 4213
- Phase 1/Phase 298
- Phase 2/Phase 371
Top conditions
- Depression422
- Anxiety415
- Alzheimer Disease341
- Autism Spectrum Disorder258
- Dementia226
- Mild Cognitive Impairment199
- Schizophrenia192
- Major Depressive Disorder189
- Cognitive Impairment157
- Insomnia152
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders85
Leading sponsors
- VA Office of Research and Development103
- Yale University95
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania51
- Karolinska Institutet50
Where studies are running
- California530
- New York268
- Massachusetts263
- Texas223
- Maryland176
- Pennsylvania175
- Florida153
- Alabama118
- Arizona117
- Connecticut113
Recruiting studies8,194 total
- NCT05466214Recruiting
School-based counseling for higher-risk young students
This trial studies whether a structured counseling approach helps elementary students who are identified as higher risk for emotional or behavior challenges. It is done in elementary schools, starting with students in grades K through 4.
Madison, WisconsinAges 4–10 - NCT05465538RecruitingPhase 1/Phase 2
PET imaging study using SV2A in older adults
This early-phase study tests a PET scan tracer called SV2A in adults age 50 and older. It aims to help researchers understand how the tracer works in the brain/body, which could support future diagnostic or treatment research.
New Haven, ConnecticutAges 50 years+ - NCT05440825Recruiting
Virtual reality relaxation for stress and sleep problems
This trial tests whether virtual reality (VR) relaxation can help people who are dealing with stress and sleep problems while receiving mental health treatment. It may help by teaching calming skills through guided VR exercises.
EnschedeAges 18 years+ - NCT05436548Recruiting
Check-ins at work to reduce burnout in primary care staff
This trial tests whether supervisor-led work check-ins can lower burnout for people who work in primary care clinics. It may help by creating regular support and communication at work.
Portland, OregonAges 18 years+ - NCT05398120Recruiting
Skills group for teens at high risk for psychosis
This study offers a skills-based group program for teens who are considered at high risk of developing a psychotic disorder. It aims to help young people cope and possibly lower the impact of early warning symptoms.
Pittsburgh, PennsylvaniaAges 13–18 - NCT05338944Recruiting
Dialectal behavior therapy for teens with obesity and low mood
This study tests whether Dialectal Behavior Therapy (DBT)—a structured skills-based counseling program—can help teens make healthier behavior changes. It is for teens who have obesity and mild to moderate symptoms of depression, and it checks whether they can follow the study plan.
Calgary, AlbertaAges 14–17 - NCT05334992Recruiting
Support for family caregivers of people with dementia
This study aims to improve mental health for people who care for someone with dementia or memory problems. If you’re an unpaid caregiver and you have anxiety or depression symptoms, this program may offer structured support to help you cope better.
Lubbock, TexasAges 18–120 - NCT05094115Recruiting
Study to improve resilience in adult soldiers
This study looks at ways to improve “resilience” (how well people cope with stress) and readiness in adult soldiers. If you’re in the right unit, joining may help the researchers test support strategies that could benefit military personnel.
Killeen, TexasAges 18 years+ - NCT05020158Recruiting
Family Talk support after a serious illness in the family
This trial tests a “Family Talk” support program for families dealing with a child’s life-threatening or life-limiting illness. It aims to help families talk and cope together during the early period after diagnosis or relapse.
StockholmAges 6 years+ - NCT04781972RecruitingPhase 4
Brain scan study of ADHD effects from methylphenidate
This study uses brain imaging (MRI) to see how methylphenidate affects brain activity in people with ADHD. It may help doctors better understand how this medicine works and who benefits most.
Baltimore, MarylandAges 6–40 - NCT04756245Recruiting
Pilot study using virtual reality plus walking support
This study tests a virtual reality activity program you can do at home, with support from an “activity buddy.” It aims to see whether the program is safe and workable for people at home, and to learn how it affects activity and thinking.
Winston-Salem, North CarolinaAges 45–80 - NCT04700878Recruiting
Compassion course study for healthcare workers under stress
This trial tests whether a digital “compassion” training course can reduce stress in people who work directly with patients. You may be offered the course (or not, depending on random assignment) to see if it improves how you feel at work.
Vaxjo, Kronoberg CountyAges 20 years+ - NCT04166071Enrolling by invitationEarly Phase 1
Testing whether opioids plus support change learning behavior
This early study tests how opioid medicine, along with social support, affects how people learn or “unlearn” certain responses. If you’re healthy and meet safety requirements, it may help researchers understand how support could change the effects of pain-related medicines on behavior.
Los Angeles, CaliforniaAges 18–35 - NCT04094428Recruiting
Study of ICU outcomes, deaths, and care costs
This study looks at what happens to people in intensive care, including deaths and hospital resource use. It may help hospitals plan better care and understand the costs of staying in the ICU.
UlmAges Any age - NCT03909477Recruiting
Study of MRI brain scans in cannabis smokers over time
This study follows people who currently or used to smoke cannabis to see how cannabis use may change certain MRI scan signals in the brain over time. You may help researchers understand the effects of cannabis smoking and how brain imaging changes can be measured safely.
London, OntarioAges 18–85 - NCT03887715RecruitingTeam says not enrolling
VNS device for long-term depression that hasn’t improved
This trial studies whether a vagus nerve stimulation (VNS) device can reduce symptoms of treatment-resistant depression. Participants either receive the VNS treatment or a no-stimulation control, to compare safety and effectiveness.
Birmingham, AlabamaAges 18 years+ - NCT07749534Recruiting
Living with spinal deformity: quality of life study
This study follows adults with spinal deformity to understand how the condition and its treatments affect daily life, emotions, and physical function. It aims to improve care and support for people like you.
LeuvenAges 18 years+ - NCT07457489Recruiting
Brain stimulation for opioid recovery
This study tests a non-invasive brain stimulation technique called TMS to see if it can reduce opioid cravings and help people who are already taking buprenorphine stay in recovery. TMS uses magnetic pulses to stimulate parts of the brain involved in addiction.
Brentwood, TennesseeAges 18–65 - NCT07750223Recruiting
Hesperidin for memory and thinking in older adults
This study tests whether a natural supplement called hesperidin (found in citrus fruits) can support brain health in older adults who are overweight or obese. It may help with memory and thinking.
Shanghai, Shanghai MunicipalityAges 55–75 - NCT05988385Recruiting
Treating sleep apnea to protect memory in older adults
This study tests whether treating sleep apnea can help protect memory and brain health in older adults. It involves using a CPAP machine or other treatments for sleep apnea and may include memory tests and brain scans over 2 years.
Tucson, ArizonaAges 55–85 - NCT05400382Recruiting
Mindfulness for depression and pain after cesarean delivery
This study tests whether a mindfulness program can help new mothers manage pain and depression after a planned cesarean delivery. You might be eligible if you are a woman of color or non-Hispanic White with a history of depression and are scheduled for a planned C-section.
Champaign, IllinoisAges 18–45 - NCT04106713Recruiting
Understanding change across different psychotherapies for anxiety and depression
This study looks at how people change during different types of psychotherapy for anxiety and depression. It aims to understand which treatments work best for different people.
Singapore, SingaporeAges 18–99 - NCT05812131Recruiting
Online training for behavioral health providers
This study tests an online training program for providers to help patients cope. If you are a behavioral health provider, you may learn new skills to support your patients.
Charleston, South CarolinaAges 18 years+ - NCT07749521Recruiting
Treating depressed parents of children with behavioural problems
This study tests a virtual group treatment to help parents with mild to moderate depression improve their own wellbeing and better support their child's emotional and behavioural health. If you are a parent with depression and have a child aged 6-11 who is struggling emotionally or behaviourally, this trial may be for you.
Toronto, OntarioAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,195 recruiting psychiatry studies from the U.S. registry right now, out of 13,258 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.