Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT06145984Recruiting
Positive Thinking Techniques to Prevent Depression Relapse
This study tests whether positive thinking exercises help people who have recovered from depression stay well and avoid relapse. Researchers will compare people with a history of depression to those who've never had depression to understand how these techniques work.
Groningen, Provincie GroningenAges 18–60 - NCT06130371Recruiting
Stress, Inflammation & Brain in Depression vs. Severe PMS
This study looks at how stress and inflammation affect the brain in women with major depression compared to women with severe PMS (PMDD). It could help find better ways to understand and treat these mood disorders.
Tübingen, Baden-WurttembergAges 18–40 - NCT06139861Recruiting
Better Sleep Study
This study tests a program to help you sleep better. It is for people who are generally healthy and do not have serious medical or mental health conditions.
Los Angeles, CaliforniaAges 12–18 - NCT06139224Recruiting
Gut Bacteria and Inflammation in HIV and Heavy Drinking
This study looks at how gut bacteria and inflammation interact in people with both HIV and heavy alcohol use. It aims to find new ways to improve health by understanding these connections.
Chicago, IllinoisAges 45–75 - NCT06151158Recruiting
Preventing suicide in high-risk youth after a crisis visit
This study tests a program to help teens and young adults who have had thoughts of suicide or made an attempt. The program provides extra support after they leave the hospital or treatment program to help keep them safe.
St. Petersburg, FloridaAges 12–24 - NCT06145555Enrolling by invitation
Sleep stabilization therapy for hospitalized depression
This study tests a quick, non-drug sleep therapy for people in the hospital for depression. It aims to help stabilize your sleep to improve your mood and recovery.
StockholmAges 18 years+ - NCT06152705Recruiting
fMRI-Guided vs. Standard Brain Stimulation for Depression
This study compares two types of repetitive transcranial magnetic stimulation (rTMS) to treat depression. One type uses a brain scan (fMRI) to guide the treatment, while the other uses a standard approach. It may help people whose depression hasn't improved with medication.
Ottawa, OntarioAges 18 years+ - NCT06129877Enrolling by invitation
Feeding difficulties study using the CHAMP app
This study collects information from families using the CHAMP App to learn more about feeding difficulties in children. It is open to patients already taking part in a related study where they agreed to use the app.
Kansas City, MissouriAges 1 month–18 years - NCT06154889Recruiting
Rehab program after shoulder stabilization surgery (Latarjet)
This study tests a new rehab program after a shoulder stabilization surgery called Latarjet. It may help you recover better if you have had a dislocated shoulder and need this surgery.
AnnecyAges 18–67 - NCT06147414Recruiting
Blood test for genetic disorders in pregnancy
This study tests a safer blood test to check for certain genetic disorders during pregnancy, instead of an invasive procedure like amniocentesis. It's for pregnant women who are at risk of passing on a known genetic condition.
ParisAges 18 years+ - NCT06149273Recruiting
Treating insomnia in primary care
This study tests a treatment for people who have had trouble sleeping for at least 3 months. It aims to help you sleep better through care you can get from your regular doctor.
TurkuAges 18 years+ - NCT06138522Recruiting
How Teens View Changes in PTSD Therapy
This study talks with traumatized teens and their therapists to understand how their therapy changes over time. It aims to improve care for young people with PTSD.
Paris, IDFAges 12 years+ - NCT06142955Recruiting
TMS therapy for depression in autism spectrum disorder
This study tests whether transcranial magnetic stimulation (TMS), a noninvasive brain stimulation technique, can help treat depression in people with autism spectrum disorder. It may help if you are between 18 and 40, have autism and depression, and are not taking medications that could interfere.
New Haven, ConnecticutAges 18–40 - NCT06132178RecruitingPhase 2
Psilocybin and rTMS for hard-to-treat depression
This study tests whether a combination of psilocybin (a psychedelic substance) and transcranial magnetic stimulation (rTMS, a noninvasive brain stimulation) can help people with treatment-resistant depression. It involves daily visits to the research center for about 2 weeks.
Austin, TexasAges 22–65 - NCT06129838Recruiting
Inflammation in Alzheimer's disease using a brain scan
This study uses a special PET scan to look for inflammation in the brains of people with Alzheimer's or related dementias. It may help researchers understand how inflammation affects memory and thinking problems.
St Louis, MissouriAges 50 years+ - NCT06145516Recruiting
Sleep program to ease pain after joint replacement
This study tests whether a sleep program can help with pain after knee or hip replacement. If you have insomnia and arthritis pain, you may be able to join before your surgery.
Uppsala, UpplandAges 18–100 - NCT06136572Recruiting
Study on assertiveness and emotions in Tourette's
This study looks at how people with Tourette's syndrome manage emotions and assertiveness. It may help doctors understand the challenges patients face.
Clermont-Ferrand, FranceAges 18 years+ - NCT06141902Enrolling by invitation
Herbal tea for stem cell donor well-being
This study tests whether a special herbal tea (Jing Si Herbal Drink) can help people who donate stem cells feel better physically and emotionally. It is for healthy stem cell donors who are willing to drink the tea as part of the study.
Hualien CityAges 20–55 - NCT06133842Recruiting
Brain blood flow and confusion after surgery study
This trial looks at how well the brain controls its own blood flow during non-cardiac surgeries. It aims to see if problems with this regulation are linked to confusion after surgery (delirium).
Boston, MassachusettsAges 60 years+ - NCT06143488Recruiting
Clot removal versus medication for mild stroke with large vessel blockage
This trial compares a procedure to remove the blockage (endovascular therapy) with the best medications alone for people who have a mild stroke caused by a large blocked artery in the brain. The goal is to see if the procedure can improve recovery better than medicine alone.
Wuhu, AnhuiAges 18 years+ - NCT06138405Recruiting
Dental training for kids and dentists
This study tests a program to help dental providers and parents interact better with children during dental visits. The goal is to make the experience less stressful and more effective for everyone.
Fayetteville, ArkansasAges 18–99 - NCT06145477Recruiting
Parenting support for preschoolers in Head Start
This study tests a new virtual program to help parents manage their preschool child's behavior and support their mental health. It is for families in Baltimore City Head Start programs.
Baltimore, MarylandAges 18–99 - NCT05945602Recruiting
Using brain signals to guide cognitive rehab in psychosis
This study looks at brain-wave or related “brain signal” measurements to better guide cognitive rehabilitation (thinking and memory skills). It may help people with long-term psychotic disorders, and it also may include healthy comparison volunteers to understand the signals.
San Diego, CaliforniaAges 18–75 - NCT05424406Recruiting
Studying sleep timing changes in people with night-shift disorder
This study looks at how changes in your body clock (circadian timing) relate to “shift work disorder” in people who work night shifts. It may help researchers understand what drives symptoms and how to better target treatment.
Novi, MichiganAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.