Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT06173752Recruiting
How exposure therapy works for OCD
This study looks at how exposure therapy helps people with OCD. It aims to understand the mechanisms behind why this treatment is effective.
San Diego, CaliforniaAges 18–65 - NCT06170047Recruiting
Parent program for foster and kinship caregivers
This study tests a parenting program designed to support foster and kinship caregivers in Ohio. It aims to help you build skills and confidence while caring for a foster child aged 2 to 8.
Cincinnati, OhioAges 2 years+ - NCT06170970RecruitingPhase 2
Solriamfetol for fatigue in multiple sclerosis
This study tests whether solriamfetol, a medication that promotes wakefulness, can reduce fatigue in people with multiple sclerosis. If you struggle with tiredness and sleepiness, this trial may help you understand how this drug works for MS-related fatigue.
Baltimore, MarylandAges 18–60 - NCT06162689Enrolling by invitation
Mental health study for mothers and families
This study follows up with mothers, children, and co-parents who took part in an earlier mental health study. Researchers want to learn how family mental health changes over time and what factors may help or challenge families.
LondonAges Any age - NCT06180837Recruiting
Can longer sleep improve heart health in overweight adults?
This study tests if getting more sleep (7+ hours) can lower certain fats in the blood called ceramides, which are linked to heart disease risk. It's for overweight adults who currently sleep less than 6.5 hours a night.
Salt Lake City, UtahAges 18–45 - NCT06174116RecruitingPhase 4
Adding lumateperone to clozapine for schizophrenia
This trial tests whether adding lumateperone, an antipsychotic medication, to clozapine can improve metabolic health in people with schizophrenia. It aims to see if this combination helps with weight, blood sugar, and cholesterol levels.
Worcester, MassachusettsAges 18–65 - NCT06157840Recruiting
Sleep program for people on buprenorphine treatment
This trial tests a mobile health sleep program for people who are on buprenorphine for opioid use disorder and have trouble sleeping. It aims to help improve sleep and support your recovery journey.
Charleston, South CarolinaAges 18 years+ - NCT06179485Enrolling by invitation
Ketamine vs. Etomidate for emergency breathing tube: long-term study
This study compares how two common medicines (ketamine and etomidate) used during emergency breathing tube placement affect long-term recovery. It is only for patients already enrolled in another related trial.
Birmingham, AlabamaAges 18 years+ - NCT06160284RecruitingPhase 1
Psilocybin for brain healing in opioid recovery
This study tests whether psilocybin, a psychedelic substance, can help change brain connections in people recovering from opioid use disorder. It involves brain scans and careful medical monitoring to explore new treatment options.
New Haven, ConnecticutAges 25–55 - NCT06158880Recruiting
Alcohol and men's sexual risk behaviors
This study looks at how alcohol affects men's decisions about sex, especially risky behaviors like not using condoms. If you join, you may help researchers understand how to reduce HIV and STI risk.
Phoenix, ArizonaAges 21–30 - NCT06167746RecruitingPhase 3
Caregiver support program for hospital to home
This study tests a program that helps caregivers of hospitalized older adults take better care of themselves while supporting their loved one. The program uses technology and coaching to improve your own health during the transition from hospital to home.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05338944Recruiting
Dialectal behavior therapy for teens with obesity and low mood
This study tests whether Dialectal Behavior Therapy (DBT)—a structured skills-based counseling program—can help teens make healthier behavior changes. It is for teens who have obesity and mild to moderate symptoms of depression, and it checks whether they can follow the study plan.
Calgary, AlbertaAges 14–17 - NCT04191811Recruiting
Using brain signals to predict CBT success for mood or sleep issues
This study tests whether brain measurements can help predict who will benefit from a type of talk therapy called CBT (cognitive behavioral therapy). If you have depression, social anxiety, or insomnia, your brain “response variability” may be used to personalize or improve treatment planning.
Huddinge, Stockholm CountyAges 18 years+ - NCT03646214Recruiting
Oral appliance to improve snoring and sleep in pregnancy
This trial tests an oral device worn during sleep to improve sleep quality for pregnant adults who snore. You may qualify if you meet specific dental and airway (throat/mouth) checks and can use the study sleep recorder and device.
Dallas, TexasAges 18–45 - NCT05611502Recruiting
Study uses brain stimulation to test attention changes
This study uses a treatment called TMS to see how it affects attention (how you focus and process information). You may be placed in a group based on how often you drink alcohol, and your eligibility depends on safety checks for MRI and TMS.
Auburn, AlabamaAges 18 years+ - NCT05621538Recruiting
Neurofeedback plus brain stimulation for alcohol use disorder
This trial studies whether combining brain “training” (neurofeedback) with noninvasive brain stimulation (TMS) can help people with alcohol use disorder. It may be offered as an additional treatment alongside care you’re already receiving.
Auburn, AlabamaAges 19–65 - NCT03817502RecruitingPhase 3
Cariprazine test for teens with schizophrenia
This trial tests whether cariprazine works and is safe for teens aged 13 to 17 with schizophrenia. It may help if your symptoms are still moderate to severe despite current care.
Culver City, CaliforniaAges 13–17 - NCT06138054Recruiting
Mobile Program for Veterans with Mental Illness and Homelessness History
This trial tests a smartphone-based program to help veterans with serious mental illness who have experienced homelessness feel more connected to their community. It aims to see if the mobile coaching can improve daily living skills and reduce feelings of isolation.
West Los Angeles, CaliforniaAges 18–65 - NCT06136195RecruitingPhase 1
Mavoglurant for alcohol craving in heavy drinkers
This trial tests whether a medication called mavoglurant can reduce alcohol cravings and drinking in people who are heavy drinkers with alcohol use disorder and are not looking for treatment.
New Haven, ConnecticutAges 21–50 - NCT06147414Recruiting
Blood test for genetic disorders in pregnancy
This study tests a safer blood test to check for certain genetic disorders during pregnancy, instead of an invasive procedure like amniocentesis. It's for pregnant women who are at risk of passing on a known genetic condition.
ParisAges 18 years+ - NCT06129877Enrolling by invitation
Feeding difficulties study using the CHAMP app
This study collects information from families using the CHAMP App to learn more about feeding difficulties in children. It is open to patients already taking part in a related study where they agreed to use the app.
Kansas City, MissouriAges 1 month–18 years - NCT06145984Recruiting
Positive Thinking Techniques to Prevent Depression Relapse
This study tests whether positive thinking exercises help people who have recovered from depression stay well and avoid relapse. Researchers will compare people with a history of depression to those who've never had depression to understand how these techniques work.
Groningen, Provincie GroningenAges 18–60 - NCT06132581Recruiting
Brain stimulation for pleasure loss in depression
This study tests a new type of brain stimulation to see if it can help people with depression who have lost the ability to feel pleasure. It uses MRI scans to guide the treatment and may help improve motivation and goal-setting.
Tallahassee, FloridaAges 18–65 - NCT06154889Recruiting
Rehab program after shoulder stabilization surgery (Latarjet)
This study tests a new rehab program after a shoulder stabilization surgery called Latarjet. It may help you recover better if you have had a dislocated shoulder and need this surgery.
AnnecyAges 18–67
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.