Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,784 recruiting studies in this area right now.
By phase
- Not applicable6,423
- Phase 2495
- Phase 1249
- Phase 3240
- Phase 4214
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety388
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder240
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress118
- PTSD104
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development102
- Yale University87
- Massachusetts General Hospital79
- Stanford University69
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts269
- New York254
- Texas209
- Maryland175
- Pennsylvania170
- Florida148
- Alabama119
- Arizona111
- Ohio104
Recruiting studies7,784 total
- NCT03618186Enrolling by invitationPhase 2
Brain scan study for African Americans age 30+
This Phase 2 study uses brain imaging (including PET and MRI) to learn more about brain changes. It may help researchers improve how brain patterns are measured and understood, which could guide future care.
Jacksonville, FloridaAges 30 years+ - NCT02225301Recruiting
Online training for childcare staff to spot child abuse
This study tests an online learning program (“module”) for people who work in childcare. It aims to help early childcare providers recognize signs of possible child abuse and respond appropriately.
Hershey, PennsylvaniaAges 18 years+ - NCT03415620Recruiting
Music listening during surgery to reduce anxiety and pain
This study tests whether listening to music around the time of surgery can lower anxiety and pain, reduce how much pain medicine you need, and improve satisfaction. You may be asked to fill out brief questionnaires before and after your procedure.
SingaporeAges 21–70 - NCT03320304Recruiting
VNS for long-term depression that hasn’t improved with treatment
This trial studies how well and how efficiently VNS therapy works for people with long-lasting or repeated major depression that hasn’t responded to enough antidepressant treatments. It may help patients who are already receiving depression treatment but are still struggling.
ViennaAges 18 years+ - NCT03388606Recruiting
Studying adolescent depression and how to treat it
This study looks closely at how depression shows up in teens and tests approaches to treatment. It may help teens and families better understand depression and get access to structured care as part of research.
Los Angeles, CaliforniaAges 11–25 - NCT03307317Recruiting
Testing brain signaling in infants at early risk
This study looks at how the brain “mirrors” or responds to actions, with the goal of finding early signs of neurodevelopmental disorders. It includes healthy adults and infants, and infants who may be at risk, to compare brain patterns early on.
Bethesda, MarylandAges 9 months–65 years - NCT03438526RecruitingPhase 4
Melatonin treatment for low-activity delirium in ICU patients
This trial tests whether giving melatonin (or a placebo) can help adults in the intensive care unit who have a specific type of confusion called low-activity delirium. It aims to improve recovery by supporting sleep–wake regulation in the ICU.
BaselAges 55 years+ - NCT03451383Recruiting
Study brain changes in older breast cancer patients
This study follows older women with newly diagnosed breast cancer to see who might develop thinking or memory problems over time. It may help researchers understand early brain risk and how treatment and other factors relate to cognitive decline.
Washington D.C., District of ColumbiaAges 60–105 - NCT03372317Recruiting
Tau brain PET imaging study for adults ages 55–90
This study uses a brain scan called PET to look at tau (a brain protein) and how it relates to thinking and memory. It may help researchers understand early brain changes, though it’s mainly for healthy people living near Columbia who have had an amyloid PET scan before.
New York, New YorkAges 55–90 - NCT03470480Recruiting
Brain stimulation for methamphetamine cravings
This study tests whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can help reduce cravings for methamphetamine in people who have stopped using it for at least 4 weeks. If you are trying to stay off methamphetamine and struggling with cravings, this treatment might help.
Portland, OregonAges 18–65 - NCT03417960Recruiting
Accelerated brain stimulation for postpartum depression
This trial studies an intensive form of noninvasive brain stimulation (treatments given through the scalp) for postpartum depression. It aims to reduce depression symptoms and improve wellbeing in people who are at least 18 and have moderate symptoms.
Charleston, South CarolinaAges 18–50 - NCT03338387Enrolling by invitationPhase 2
Test effects of gut hormones in bulimia
This trial studies how growth-related and gut hormones affect ghrelin, a hunger-related hormone, in people with bulimia. It may help researchers understand the body changes behind bulimia and how hormones and appetite signals work.
Ages 18–30 - NCT03503331RecruitingPhase 2
Alzheimer’s imaging add-on for research center patients
This study adds special brain scans (MRI and a PET scan) for people already enrolled in the UAB Alzheimer’s Disease Center research program. The scans are used to learn more about brain changes in Alzheimer’s, which may help researchers find better ways to measure and understand the disease.
Birmingham, AlabamaAges 50 years+ - NCT03506867Enrolling by invitation
Test program to help recent smokers in Ottawa or Toronto
This trial offers a health program for people age 16+ who smoked recently and live in Ottawa or Toronto. It aims to help with quitting and follow-up over one year, especially for people facing financial hardship or housing instability.
Ottawa, OntarioAges 16 years+ - NCT03380078Enrolling by invitation
Training programs to better support kids with autism
This study tests an organized training plan meant to help mental health programs and schools support children with autism. It involves leaders, therapists/providers, and parents who complete brief surveys and assessments to see what improves care and services.
Sacramento, CaliforniaAges 18 years+ - NCT03370224Enrolling by invitation
Story memory training for older adults
This study tests a memory-skills training approach (the Modified Story Memory Technique) to help older adults with aging-related memory changes. You may be asked to do memory exercises, and some people may also complete an optional brain MRI scan.
East Hanover, New JerseyAges 65 years+ - NCT03389100Enrolling by invitationPhase 2
Tau PET brain scan study for people without dementia
This trial studies how tau (a protein linked to Alzheimer’s and related conditions) shows up on a special brain scan called tau PET. It also uses MRI and blood work to understand brain changes and who may be at risk, helping researchers improve future diagnosis.
New York, New YorkAges 55–69 - NCT03396276Enrolling by invitationPhase 4
Emergency system to help people stop opioid misuse
This Phase 4 study tests an “emergency opioid engagement system” that aims to help people who are opioid-dependent start stopping opioid use. If you’re willing to stop and can safely participate, the program may offer structured support when you’re in the emergency setting.
Houston, TexasAges 18 years+ - NCT03457402Recruiting
Training kids to wait for bigger rewards
This study tests a learning task (with a tablet) to help children practice waiting for a bigger reward instead of acting on impulse right away. It may be useful for young children who show very high impulsivity or hyperactivity.
Sacramento, CaliforniaAges 3–6 - NCT03313011Recruiting
Study brain patterns in progressive apraxia of speech
This study looks at brain changes in two types of progressive apraxia of speech, a condition that slowly worsens speech clarity. It may help researchers better understand the brain basis of your speech symptoms and how these types differ.
Rochester, MinnesotaAges 18 years+ - NCT03308773Enrolling by invitation
Prevention program for people at risk of type 2 diabetes
This trial looks at a personalized prevention approach for people who are at risk of developing type 2 diabetes. It may help by targeting your specific health factors before diabetes starts.
Ages 18–100 - NCT02649985RecruitingPhase 1/Phase 2
PET brain scan study for several brain and mood conditions
This early-phase study uses PET and MRI brain scans to better understand brain changes in multiple sclerosis, Alzheimer’s disease, and other neurological or mood conditions. The goal is to test whether these scans can show disease-related differences and guide future treatments.
Boston, MassachusettsAges 18–85 - NCT03225144Recruiting
Study of gene and disease changes in ALS and frontotemporal dementia
This study looks at complex brain and body changes in people with ALS and frontotemporal dementia (FTD), or related disorders. If you have one of these diagnoses—or a known gene mutation that can cause ALS/FTD—you may be able to help researchers learn how the conditions progress.
Bethesda, MarylandAges 18–110 - NCT03065335RecruitingPhase 1
Ketamine plus brain imaging to study response in depression
This early-stage study tests how ketamine given once and then repeatedly may change brain signals and related biomarkers in people with major depression. If you’re eligible, the team will use brain imaging and assessments to see who responds and why.
Bethesda, MarylandAges 18–65
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,784 recruiting psychiatry studies from the U.S. registry right now, out of 12,489 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.