Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,199 recruiting studies in this area right now.
By phase
- Not applicable6,804
- Phase 2511
- Phase 1256
- Phase 3244
- Phase 4214
- Phase 1/Phase 298
- Phase 2/Phase 372
Top conditions
- Depression419
- Anxiety411
- Alzheimer Disease342
- Autism Spectrum Disorder258
- Dementia227
- Mild Cognitive Impairment201
- Schizophrenia192
- Major Depressive Disorder188
- Cognitive Impairment157
- Insomnia154
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders83
Leading sponsors
- VA Office of Research and Development104
- Yale University96
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania52
- Karolinska Institutet50
Where studies are running
- California528
- New York267
- Massachusetts261
- Texas224
- Maryland176
- Pennsylvania174
- Florida154
- Alabama118
- Arizona117
- Connecticut114
Recruiting studies8,198 total
- NCT06721559Recruiting
Home program for older adults with depression and mobility issues
This study tests a home-based program called Empower@Home for older adults who have depression and trouble moving around. It aims to see if the program helps improve mood and daily life—without adding extra outside therapy.
Ann Arbor, MichiganAges 50 years+ - NCT06723041Recruiting
Acupressure to lower anxiety during cancer treatment
This trial tests if acupressure—a gentle pressure technique on specific points—can help reduce anxiety in people receiving cancer therapy. It compares nurse-led acupressure sessions with learning self-administered acupressure.
Rochester, MinnesotaAges 18 years+ - NCT06721195Recruiting
Study of Euphoria from Remimazolam During GI Scopes
This trial studies a sedative called remimazolam and how it makes people feel during routine upper and lower GI scope procedures. It may help doctors understand which patients are more likely to feel a sense of euphoria (a feeling of intense happiness) from the medicine.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06721312Recruiting
Heart rate tracking for doctor stress
This study uses a smartphone app to track your heart rate changes over time. It aims to understand how doctors' stress and recovery patterns relate to their well-being, resilience, and burnout.
AberdeenAges Any age - NCT07417839Recruiting
Toy nebulizer vs distraction cards for children's fear during breathing treatment
This study compares using a toy-shaped nebulizer or distraction cards to reduce fear in children aged 3-6 who are receiving their first breathing treatment for asthma or bronchitis. It aims to see which method makes the experience less scary and increases parent satisfaction.
Baghdad, MouslAges 3–6 - NCT06712147Recruiting
MHE3: health study for Hispanic residents
This study tests ways to help Hispanic/Latino families overcome health obstacles. You may join if you live in certain San Jose zip codes.
Palo Alto, CaliforniaAges 18–65 - NCT06709404Recruiting
Telehealth support for caregivers of HIPEC patients
This study tests a telehealth program to help caregivers manage distress and financial stress while caring for someone receiving a special surgery (CS+HIPEC). It aims to see if the program improves caregivers' well-being.
Winston-Salem, North CarolinaAges 18 years+ - NCT06703060Recruiting
A trauma-informed approach to help Black women start PrEP
This study tests a program that helps Black women start PrEP (a daily pill to prevent HIV). It focuses on understanding and addressing past trauma to make it easier to take PrEP, and is designed for women who have not used PrEP before.
Baltimore, MarylandAges 18 years+ - NCT06633900RecruitingPhase 2/Phase 3
Testing naltrexone to prevent overdose in stimulant users
This trial tests whether naltrexone, a medication that blocks the effects of opioids, can help prevent overdose in people who use stimulants like cocaine or methamphetamine. It may be a good fit if you are at risk for HIV or living with HIV, and have a stimulant use disorder or use stimulants at least 10 days per month.
San Francisco, CaliforniaAges 18 years+ - NCT06699251Recruiting
Brief chat with your doctor about alcohol or cannabis for teens
This study tests whether a short, one-time conversation with a primary care provider can help teens who are at risk for alcohol or cannabis use. It's designed for young people ages 12–17 who get care at two specific health systems.
Commerce, CaliforniaAges 12–19 - NCT05957848RecruitingPhase 2
Guanfacine for teens with cannabis use problems
This Phase 2 study tests whether extended-release guanfacine can reduce cannabis use in adolescents and young adults. It may help by targeting brain pathways that can drive cravings or continued use.
Parkville, VictoriaAges 12–25 - NCT05956392Recruiting
Personal plan to reduce kids’ screen time for better sleep
This trial tests a personalized program to help children use screens less in order to improve sleep, mood, and brain health. It’s for children who regularly sleep under 8 hours on school nights and spend more than 2 hours per day on media.
SingaporeAges 6–12 - NCT05814640RecruitingPhase 1/Phase 2
STAR-AD: Testing stepwise treatment for teen depression
This trial tests a step-by-step approach to treating moderate-to-severe depression in teens. It may help find a treatment path that improves mood while keeping care safe, including for some teens who have suicidal thoughts but do not need inpatient care.
Chongqing, ProvinceAges 13–18 - NCT06673589Recruiting
Study on brain synchrony during social interaction
This trial looks at how brain activity syncs between people, focusing on those with different levels of social interaction. It may help understand social connection better.
Fairfield, IowaAges 18–50 - NCT06669624Recruiting
Help for parents and toddlers facing tough times
This study tests a program to help parents and young children build resilience. If your toddler has faced hard times, the program offers support to strengthen your relationship and help your family thrive.
Chapel Hill, South CarolinaAges 18 years+ - NCT07423546RecruitingPhase 1/Phase 2
Brain scan study of Cobenfy in schizophrenia
This study tests a new medication called Cobenfy (also known as trospium) using brain scans to see how it affects dopamine in people with schizophrenia. If you have schizophrenia and are not currently on antipsychotics, you may be able to join.
New York, New YorkAges 18–50 - NCT07368556Recruiting
Nursing care program for teens who self-harm
This study tests a nursing care program designed to help teenagers who self-harm. The program is based on a caring theory and aims to support adolescents aged 14 to 18.
AntalyaAges 14–18 - NCT06659913Recruiting
Increasing physical activity for body and mind
This study is testing whether increasing physical activity can improve both your body and mind. It's for people who are currently not very active and want to see if moving more makes a difference.
TrondheimAges 12–17 - NCT06656416RecruitingPhase 2
ALTO-100 for bipolar depression
This trial tests an investigational drug called ALTO-100 in people with bipolar I or II who are currently experiencing depression. It looks at whether this new medicine can help improve depression symptoms when taken alongside your usual mood stabilizer or antipsychotic medication.
Chandler, ArizonaAges 18–70 - NCT06652711Recruiting
A mental health app study for Hispanic immigrants
This trial tests a phone app designed to help improve the mental health and emotional well-being of recent Hispanic immigrants in the U.S. who speak Spanish. If you qualify, you may be able to use the app and help researchers see if it can make a difference.
Austin, TexasAges 18 years+ - NCT07356492Recruiting
Support program for transitioning service members at moderate suicide risk
This study tests a program to help service members who are at moderate risk for suicide as they transition from military to civilian life.
The Bronx, New YorkAges 18 years+ - NCT05946512Recruiting
Yoga breathing plus lung MRI measurements for post-COVID symptoms
This study uses breathing exercises from yoga and MRI (a scan of the body) measurements to see how well yoga breathing can improve ongoing breathing symptoms after COVID-19. It also compares results in a few other specific groups and healthy volunteers.
Innsbruck, TyrolAges 18–50 - NCT06639477Recruiting
Mood and sleep improvement study for older adults
This study tests whether adding a sleep treatment to regular depression medication can improve both mood and sleep in adults aged 55 and older. It may help if you have ongoing depression, sleep problems, and are already taking antidepressant medication.
Los Angeles, CaliforniaAges 55 years+ - NCT06940843Recruiting
Hopeful and Healthy Living program study
This study tests a program called Hopeful and Healthy Living to see if it helps people with serious mental illness feel better and live healthier. It's for adults 50 and older who are part of specific support programs in Boston.
Boston, MassachusettsAges 50 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,199 recruiting psychiatry studies from the U.S. registry right now, out of 13,332 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.