Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,957 recruiting studies in this area right now.
By phase
- Not applicable1,542
- Phase 2142
- Phase 384
- Phase 181
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma73
- Periodontal Diseases50
- Dental Caries45
- Head and Neck Cancer35
- Gingivitis33
- Oral Cancer31
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Maryland21
- Massachusetts21
- Florida20
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,957 total
- NCT07711431Recruiting
Connection between gum disease and ongoing neck pain
This study looks at whether there is a link between gum (periodontal) disease and long-term neck pain without a clear cause. If you are between 30 and 55, have most of your own teeth, and don't take regular pain medicine, you may be able to help doctors understand this connection.
Niğde, Niğde ProvinceAges 30–55 - NCT07712432Recruiting
Insomnia and pain after dental surgery study
This study looks at how sleep problems might affect pain after dental surgery. If you are having a tooth removed, you may be able to help by filling out some questionnaires.
RomaAges 18 years+ - NCT07707063RecruitingPhase 4
Gum disease treatment with I-PRF, iodine, or laser in smokers and non-smokers
This trial tests whether adding I-PRF (a concentrate from your own blood), povidone-iodine, or laser treatment to standard deep-cleaning helps smokers and non-smokers with gum disease. You may qualify if you have moderate to severe gum disease with at least one bleeding pocket in each area of your mouth.
Tunis, Mont FleuryAges 18 years+ - NCT07711132Recruiting
Remineralizing toothpaste for early cavities in teens
This trial tests three different treatments for repairing very early cavities on tooth enamel: a nano-eggshell paste, a special milk protein paste (CPP-ACP), and a standard fluoride paste. It is for teenagers and young adults who have a few small spots of early decay and a moderate to high risk of getting cavities.
Al MansurahAges 15–20 - NCT07710391Recruiting
3D printed brace for children with underbite
This trial tests a special 3D-printed brace to fix underbite in children aged 8-13 who still have growing upper jaws. The brace encourages the upper jaw to grow forward and corrects the bite.
BaghdadAges 8–13 - NCT07706985RecruitingPhase 3
Immunotherapy for advanced nasopharyngeal cancer
This trial tests a new combination of chemotherapy and immunotherapy drugs for advanced nasopharyngeal cancer that has not spread to distant parts of the body. The goal is to see if this approach works better than standard treatment.
Guangzhou, GuangdongAges 18–70 - NCT07711626Recruiting
Foot massage and ear stimulation for head and neck cancer symptoms
This study tests whether foot massage (reflexology) and a mild nerve-stimulation device on the ear can help reduce side effects during chemotherapy and radiation for head and neck cancer.
Hualien CityAges 30–75 - NCT07709195RecruitingPhase 2
Chlorophyllin to reduce mouth sores from radiation before transplant
This trial tests whether taking chlorophyllin can reduce mouth sores caused by total body radiation given before a stem cell transplant. The goal is to make the treatment easier to tolerate.
Navi Mumbai, MaharashtraAges 12–65 - NCT07714265Recruiting
Gum thickening around dental implants: comparing three methods
This trial compares three techniques to thicken gum tissue around a single dental implant in the back of the lower jaw. It may help if you have thin gums and need a dental implant.
CairoAges 20 years+ - NCT07714837Recruiting
Orofacial pain and oral health in amateur orchestra musicians
This study looks at how playing in an amateur orchestra may relate to orofacial pain (pain in the face, jaw, or mouth) and oral health-related quality of life. By completing a questionnaire, you can help researchers understand these connections.
GöttingenAges 18 years+ - NCT07709286RecruitingPhase 1
New tooth stain treatment compared to standard acid microabrasion
This study tests a new product called Antivet to see if it removes tooth stains better than regular acid treatments. It may help people with mild to moderate tooth discoloration.
Badr, Cairo GovernorateAges 16–50 - NCT07706647Recruiting
Oil pulling for gum health trial
This study tests if oil pulling (swishing oil in your mouth) can reduce gum inflammation and bleeding. It compares oil pulling to a standard mouthwash to see which is better for gum health.
San Antonio, TexasAges 18–70 - NCT07707323Recruiting
Testing photo software for tooth color matching
This study tests a new photo-analysis software that helps dentists match the color of a tooth-colored filling (resin composite) to your natural teeth. It only involves taking pictures of your upper front teeth, and may lead to more natural-looking results.
Sixth of October, Giza GovernorateAges 18–45 - NCT06639009Recruiting
Laser treatment for better mouth opening in oral fibrosis
This study tests if a special laser therapy (photobiomodulation) helps people with oral submucous fibrosis open their mouths wider. It's for people who haven't had other treatments for this condition in the last three months.
New Delhi, National Capital Territory of DelhiAges 18–99 - NCT06642415Recruiting
High magnification microscope for tooth root surgery
This trial compares two ways of doing a special tooth surgery (endodontic microsurgery) to see if using a high-magnification microscope helps you feel better after the procedure. If you have a tooth that still hurts or stays infected after a previous root canal, this study might be for you.
Rohtak, HaryanaAges 18–55 - NCT06640205Recruiting
New treatment for painful tooth pulp in molars
This trial tests two different materials to treat the inflamed pulp in your back teeth. It compares a special type of blood concentrate (I-PRF) with a mix of nano MTA and blood concentrate to see which is better at saving the tooth and relieving pain.
CairoAges 15–30 - NCT06642870Recruiting
Self-management programme for rare rheumatic conditions
This trial is developing a self-management programme for people with rare rheumatic conditions like lupus, vasculitis, myositis, or Sjogren syndrome. It aims to help participants better manage their condition and improve their quality of life.
BristolAges 18 years+ - NCT04981145RecruitingPhase 4
Iguratimod for Sjögren’s syndrome symptoms and safety
This trial studies whether iguratimod improves symptoms in people with primary Sjögren’s syndrome, and checks how safe it is. It focuses on people with confirmed disease markers (anti-SSA/Ro-60) and ongoing dry eyes and dry mouth.
Hangzhou, ZhejiangAges 18–70 - NCT05584566Recruiting
Bone growth treatment before dental implants: two materials compared
This study compares two bone-building products used to repair a missing “bone wall” in the jaw so dental implants can be placed. You may be able to help find which material works better for guided bone regeneration and implant readiness.
JerusalemAges 18 years+ - NCT07703007Enrolling by invitation
Clear aligners for growing kids with mild underbite
This study tests whether clear aligners can fix a mild underbite in growing children aged 8 to 11. It compares how well the aligners move teeth and jaws compared to other treatments.
Al Mansurah, Dakahlia GovernorateAges 8–11 - NCT07702448Recruiting
Jaw surgery and its effect on mood and looks
This study looks at how jaw surgery affects your mood and how you feel about your appearance. You will answer questions one week before surgery and again 6 months after, and you need to use social media as part of the research.
Kirikkale, KırıkkaleAges 18–40 - NCT07702149Recruiting
Diet for Behcet's disease patients with ringing in the ears
This trial tests whether a special diet can help ringing in the ears (tinnitus) in people with Behcet's disease who also have obesity. The goal is to see if dietary changes reduce tinnitus symptoms.
Giza, DokkiAges 40–55 - NCT07702123Recruiting
Physical activity study for women with Behcet's and metabolic syndrome
This study tests if a physical activity program helps women who have both Behcet's disease and metabolic syndrome. It aims to improve their health and well-being.
Giza, DokkiAges 40–50 - NCT07703345Recruiting
Saliva markers in people with diabetes and gum disease
This study checks whether certain substances in saliva can help detect gum disease in people with type 2 diabetes. It compares the levels of these substances in people with diabetes and gum disease, people with gum disease only, people with diabetes only, and healthy volunteers.
Konya, KonyaAges 18–80
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,957 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,729 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.