Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,957 recruiting studies in this area right now.
By phase
- Not applicable1,542
- Phase 2142
- Phase 384
- Phase 181
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma73
- Periodontal Diseases50
- Dental Caries45
- Head and Neck Cancer35
- Gingivitis33
- Oral Cancer31
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Maryland21
- Massachusetts21
- Florida20
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,957 total
- NCT07727655Recruiting
Enamel protein for immediate lower molar implants
This trial is testing a special enamel protein (Emdogain) placed around a new dental implant right after removing a broken lower molar. It aims to see if this helps the implant heal better.
Al Mansurah, Dakahlia GovernorateAges 18–45 - NCT07726199Recruiting
Neck treatment approaches for oral cancer without neck spread
This study compares different ways to treat the neck in patients with early-stage oral cancer that hasn't spread to the neck. The goal is to find which approach works best while keeping side effects low.
Kolhāpur, MaharashtraAges 21–75 - NCT07727044Recruiting
Color and sensitivity of MIH teeth in children
This study looks at whether the color of spotted first permanent molars (caused by MIH) is linked to tooth sensitivity. It compares children with MIH to children with healthy teeth to understand the connection between color and pain.
Basel, Canton of Basel-CityAges 5–8 - NCT07732127Recruiting
Finding early cavities with fluorescent starch nanoparticles
This trial tests a new way to spot very early cavities using fluorescent starch nanoparticles, and compares it to saliva tests. It might help detect tooth decay before it needs a filling.
Shibīn al Kawm, MenoufiaAges 18–40 - NCT06633627Recruiting
Brain response study for tooth sensitivity
This study looks at how your brain responds to tooth sensitivity. Researchers will test a simple air puff on your teeth and measure brain activity to better understand nerve signals from sensitive teeth.
SheffieldAges 18 years+ - NCT06634017RecruitingPhase 1/Phase 2
Platelet-rich fibrin gel to speed up tooth movement with braces
This study tests whether a special gel made from your own blood (platelet-rich fibrin) can speed up tooth movement after a premolar extraction. You would be wearing braces, and one side of your mouth gets the gel while the other side is the control, so we can see if it works.
Karachi, SindhAges 18–45 - NCT07722715Recruiting
AmbiJet treatment for gum disease around dental implants
This study tests a device called AmbiJet to treat gum infections around dental implants. It may help people with early to moderate bone loss caused by implant-related gum disease.
RomnyAges 18–65 - NCT06262035Recruiting
Gum and implant disease tissue profile study
This study looks at the genetic and bacterial profiles in gum disease and implant infections. It might help find new ways to diagnose or treat these conditions.
StockholmAges 18 years+ - NCT07718061Recruiting
Bacteria in dental plaque with orthodontic retainers
This trial studies the types of bacteria found in dental plaque from people who have orthodontic retainers after braces. It aims to understand how retainers affect oral bacteria.
MurciaAges 18–40 - NCT07717229Recruiting
Biofeedback and VR for kids during dental injections
This trial tests if a video game-like biofeedback tool (BrightHearts) or virtual reality can help children feel calmer during a numbing injection for dental work. It may be a good fit for healthy kids ages 7–12 who need a shot in the lower jaw.
GizaAges 7–12 - NCT07719205Recruiting
Pre-visit imagery for children's dental care
This trial tests a tactile pre-visit imagery strategy to help children aged 4 to 10 years who have never had dental treatment before. The goal is to see if it reduces anxiety and improves their first experience with a filling or crown.
Los Angeles, CaliforniaAges 4–10 - NCT07723612Recruiting
Spirulina for mouth ulcers from radiation or other causes
This trial tests if spirulina supplements can prevent or heal mouth ulcers caused by radiation therapy or other conditions like canker sores. Participants take spirulina and are monitored to see if their ulcers improve.
Yiwu, ZhejiangAges 18–100 - NCT07719764Enrolling by invitation
Implant stability with two different drilling methods for molar replacement
This trial compares two drilling techniques for placing a dental implant right after removing a lower molar. It aims to see which method gives better initial stability of the implant, which is important for long-term success.
RiyadhAges 20–50 - NCT07717307Recruiting
Comparing two neck surgeries for oral cancer spread
This trial tests whether a smaller neck surgery works as well as a larger one for people with oral cancer that has spread to one lymph node. The goal is to see if less extensive surgery can reduce side effects while still controlling the cancer.
Kolhāpur, MaharashtraAges 21–75 - NCT07718477Recruiting
Comparing child and parent pain during dental numbing
This study compares the pain a child feels during a numbing injection at the dentist to the pain the parent thinks the child is feeling. It helps doctors understand the difference between a child's actual pain and what parents perceive, which may improve how pain is managed during dental visits.
Clermont-FerrandAges 6–15 - NCT07716254Recruiting
Dental cavity risk quiz study for Egyptian adults
This study tests a new questionnaire to see how well it can predict your risk of cavities. You will answer questions about your teeth and habits, and your answers will be compared with a dentist's exam.
Giza, Sixth of OctoberAges 18–65 - NCT07718932Recruiting
Healing gel for wisdom tooth extraction recovery
This trial tests a regenerative gel placed in the socket after wisdom tooth removal to improve healing. It may reduce pain, swelling, and speed up recovery.
ThessalonikiAges 18–35 - NCT07718620Recruiting
HPV-related throat cancer radiation trial
This trial tests whether radiation or chemoradiation works well for HPV-positive throat cancer. It may be an option if you have this type of cancer and are getting or have already had surgery.
Brno, Czech RepublicAges 18 years+ - NCT07715773Recruiting
Oral health program for college students
This study tests a program based on the Extended Health Belief Model to help college students improve their oral health habits like brushing and flossing. It might help you build better routines for keeping your teeth and gums healthy.
Basra, Basra GovernorateAges 18–25 - NCT07723404Recruiting
Comparing two ways to scan dental implants for a new bridge
This trial compares two techniques for scanning dental implants in the upper jaw to make a new permanent bridge or denture. It aims to find which method gives a more accurate fit.
Shibīn al Kawm, Shibin AlkomAges 20–60 - NCT07722390Recruiting
Injection treatment for deep gum pockets
This study tests whether injecting a special substance made from your own blood can help treat deep gum pockets without surgery. It may be an option for people with advanced gum disease who have already had initial cleaning.
CairoAges Any age - NCT06350110RecruitingPhase 1/Phase 2
CAR T cells for lupus
This trial tests a new type of CAR T cell therapy for people with active lupus that has not responded to other treatments. It uses specially engineered cells to target and eliminate certain immune cells that are causing the disease, with the goal of reducing symptoms and preventing flare-ups.
Beijing, Beijing MunicipalityAges 18–90 - NCT06641011Recruiting
Sealing molars with enamel spots: rinsing vs blotting
This study tests whether rinsing off or blotting dry a special silver fluoride liquid before placing a tooth sealant helps the sealant last longer on molars affected by a common condition called molar-incisor hypomineralization. The goal is to find the best way to protect these teeth from cavities.
AnkaraAges 6–14 - NCT07712939RecruitingPhase 1
Study of CND319 for rheumatic diseases
This study tests a new drug called CND319 in healthy volunteers and people with rheumatoid arthritis or Sjögren's disease. The goal is to see if it is safe and how the body responds to it.
Melbourne, VictoriaAges 18–65
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,957 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,729 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.