Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,057 recruiting studies in this area right now.
By phase
- Not applicable1,634
- Phase 2148
- Phase 183
- Phase 381
- Phase 459
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma80
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Oral Cancer35
- Head and Neck Cancer34
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University52
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California39
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,057 total
- NCT07715773Recruiting
Oral health program for college students
This study tests a program based on the Extended Health Belief Model to help college students improve their oral health habits like brushing and flossing. It might help you build better routines for keeping your teeth and gums healthy.
Basra, Basra GovernorateAges 18–25 - NCT07542665Recruiting
Aromatherapy vs Music for Calming Children During Dental X-rays
This study tests whether calming scents (aromatherapy) or soothing music helps children feel less anxious during a routine dental X-ray called panoramic radiography. Researchers want to see which approach works better to make the experience easier for kids.
NiğdeAges Any age - NCT06381414Recruiting
Childhood early oral aging: causes and effects on teeth
This study looks at why some young children have early signs of oral aging and how it affects their bite. It aims to find the causes and possible consequences for kids ages 3 to 6.
São Paulo, São PauloAges 3–6 - NCT06734325Recruiting
Mobile health program for braces patients
This study uses text messages on WhatsApp to help young people with braces improve their brushing habits. It will test whether a simple mobile program can keep your teeth cleaner and help you learn more about oral health.
AlexandriaAges 16–25 - NCT06517030Recruiting
Rebuilding bone for a same-day dental implant
This study compares two types of bone-graft materials used to rebuild the bone after a tooth is removed, so that a dental implant can be placed right away. If successful, this could mean fewer surgeries and faster recovery for people who need a single tooth replaced.
Milan, MiAges 22–70 - NCT07155798Recruiting
Bamboo vs. plastic toothbrush for plaque removal in teens
This trial compares a bamboo toothbrush to a regular plastic toothbrush to see which one does a better job removing plaque. If you are a teenager in good health, you can help find out which brush is better for your teeth and the planet.
CairoAges 12–18 - NCT07532161Recruiting
Fibrin and Laser Treatment for Gummy Smile Surgery
This study compares two treatment approaches—liquid fibrin (a clotting substance) and soft laser therapy—to help healing and prevent relapse after surgery to reduce a gummy smile caused by an overactive upper lip. The goal is to find which method works better for long-term results.
Damascus, Rif-dimashq GovernorateAges 18–50 - NCT07017062Recruiting
Study of ceramic veneers bonded with two self-adhesive dental cements
This trial compares two types of self-adhesive resin cements for bonding ceramic occlusal veneers. It aims to see which cement works better for restoring back teeth while keeping your natural tooth structure.
CairoAges 21 years+ - NCT07586631Recruiting
Silver Diamine Fluoride Effects on Baby Teeth Over Time
This study looks at how a special silver-based liquid (silver diamine fluoride) affects the inner health of baby teeth over the long term. Researchers will monitor teeth that were previously treated with this liquid to understand if it helps protect teeth and keep them healthy.
CairoAges 7–10 - NCT07593131Recruiting
Studying dental implant crowns in the front upper teeth
This study looks at why some dental implant crowns (artificial teeth anchored by implants) in the front upper jaw sit lower than they should. Researchers want to understand what factors affect how well these implants are positioned to help improve future placements.
StockholmAges 18 years+ - NCT06640218Recruiting
Comparing two ultrasound tools for tooth pain after root canal
This trial tests two different ultrasound methods used during root canal treatment to see which one reduces pain better afterwards. It focuses on people with a specific kind of tooth pain and infection.
Cairo, New CairoAges 18–40 - NCT06409923RecruitingPhase 1
Comparing Herbst vs Invisalign for jaw alignment in teens
This trial compares two different braces (a Herbst appliance and Invisalign MA) to see which works better for teenagers whose upper jaw is too far forward. It's for kids who are still growing and have a specific type of overbite.
AnderlechtAges Up to 15 years - NCT06977009Recruiting
Does tooth grinding relief help with post-dental pain?
This study tests whether reducing a tooth's contact with its opposite tooth before root canal treatment can lower pain after the procedure. It's for people with a dead nerve in a back molar that needs a crown.
Amman, Amman GovernorateAges 18–70 - NCT07579377Recruiting
Denture design and satisfaction in older adults
This study tests whether a specific denture design feature (palatal rugae patterns) affects how satisfied patients are with their new complete dentures and their quality of life. Complete dentures replace all missing teeth in the upper or lower jaw.
Karachi, SindhAges 40–80 - NCT06683833RecruitingPhase 4
Comparing materials for protecting tooth nerves in deep cavities
This study compares three materials used to protect the nerve inside a deep cavity. If you have a deep cavity in a live tooth, you may be able to join and help find which material works best.
CairoAges 22–45 - NCT06753396Recruiting
Effect of injectable platelet-rich fibrin on gum tissue around dental implants
This trial tests whether a treatment made from your own blood (injectable platelet-rich fibrin) can help improve thin or narrow gum tissue around dental implants. It may be an option if you have less than 2 mm of gum width or thickness around your implant.
KütahyaAges 18 years+ - NCT06430762Recruiting
Study of risk factors for jaw bone damage from certain drugs
This study looks at people who have jaw bone damage (osteonecrosis) caused by medications. Researchers want to understand what treatments and risk factors are linked to this condition to help improve care.
IstanbulAges 18–110 - NCT07506993Recruiting
Inflammation in clear aligners with attachments
This study looks at gum inflammation in people using clear aligners with or without small attachments on their teeth. It may help understand how aligners affect oral health.
Lincoln, NebraskaAges 14–35 - NCT05989061Recruiting
Comparing PEEK vs. Titanium Healing Caps for Front Tooth Implants
This trial compares two types of custom healing caps (PEEK or titanium) placed on dental implants in the front part of the mouth. It's for people who need a single implant and have good bone and gum health.
CairoAges 20–50 - NCT07719764Enrolling by invitation
Implant stability with two different drilling methods for molar replacement
This trial compares two drilling techniques for placing a dental implant right after removing a lower molar. It aims to see which method gives better initial stability of the implant, which is important for long-term success.
RiyadhAges 20–50 - NCT06980870RecruitingPhase 2
Pain medicine before root canal for less discomfort
This study tests whether taking ibuprofen or dexamethasone before a root canal can help reduce pain afterward. It's for people with a painful, inflamed tooth nerve who haven't already taken pain medicine for it.
RawalpindiAges 18–50 - NCT06442904Recruiting
Digital education for better dental X-rays
This trial tests a digital education program to help dental professionals take better X-rays. It's for dental staff in general dentistry in Västerbotten, Sweden.
UmeåAges 18 years+ - NCT07719205Recruiting
Pre-visit imagery for children's dental care
This trial tests a tactile pre-visit imagery strategy to help children aged 4 to 10 years who have never had dental treatment before. The goal is to see if it reduces anxiety and improves their first experience with a filling or crown.
Los Angeles, CaliforniaAges 4–10 - NCT07527351Recruiting
Testing a laser imaging tool for gum health assessment
This study tests a new laser imaging technology that measures blood flow in gum tissue to see if it's accurate and reliable. Researchers want to understand if this tool could help dentists better assess gum health and healing after surgery.
Madrid, MadridAges 18 years+
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,057 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,953 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.