Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,057 recruiting studies in this area right now.
By phase
- Not applicable1,634
- Phase 2148
- Phase 183
- Phase 381
- Phase 459
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma80
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Oral Cancer35
- Head and Neck Cancer34
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University52
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California39
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,057 total
- NCT07660146Recruiting
Predicting extraction needs for orthodontic treatment
This trial tests a method to help dentists decide if you need tooth extractions before braces. Researchers will look at dental models to see if this analysis tool is accurate.
Cairo, Giza GovernorateAges 12 years+ - NCT07509281Recruiting
How implant parts affect healing and gum health
This trial compares different shapes and heights of the abutment (the connector piece between the implant and crown) to see how they affect gum and bone healing. It is for people who need a single or few back teeth replaced with a dental implant.
Valencia, ValenciaAges 18 years+ - NCT06768424Recruiting
Treating deep gum pockets with laser or scalpel and platelet gel
This study compares two ways to fix deep gum pockets around teeth: a laser (MIST) or a traditional scalpel (GBT). Both methods use a gel made from your own blood (PRF) to help healing. The goal is to see which works better.
Budapest, BudapestAges 18–65 - NCT06988098Recruiting
Comparing cleaning agents for tooth sealants in children
This study compares different cleaning agents used before placing tooth-colored sealants on the back teeth of children. The goal is to see which agent helps the sealants last longer and protect teeth better from cavities.
Tokat ProvinceAges 6–9 - NCT07191262Recruiting
Comparing mouth rinses after tooth extraction and bone graft
This study compares three different mouth rinses (one with EDTA, one with chlorhexidine, and one with essential oils) after tooth extraction and bone grafting. It aims to find which rinse helps keep the area clean and promotes healing.
Birmingham, AlabamaAges 18–85 - NCT07190950Recruiting
Laser therapy for wisdom tooth removal healing
This study tests whether a low-level laser (a gentle light treatment) can help your gums and jawbone heal better after your lower wisdom teeth are removed. It may reduce pain and speed up recovery.
Ho Chi Minh CityAges 18 years+ - NCT07626827Recruiting
3D-Printed Dentures: Digital vs. Hybrid Methods
This study compares two ways of making 3D-printed dentures to see which one fits better, works better, and makes patients happier. It's for people who are completely missing all teeth in both jaws.
Samborondón, GuayasAges 50–90 - NCT06477887Recruiting
Tooth socket preservation after extraction using dentin grafts
This trial tests two ways to preserve the bone and gum after a tooth is pulled. It compares using your own tooth material (dentin) versus a donor’s tooth material to help the socket heal better.
Cairo, Cairo, Elmanil, Egypt, 4240101Ages 18–60 - NCT06477874Recruiting
Comparing bone drills for implants in jaw grafts
This study tests a new way of drilling bone for placing dental implants in people who have already had a jawbone graft from the hip. It aims to which drilling method works best for helping the implant to secure firmly.
CairoAges 18–55 - NCT07509476Recruiting
Bone changes after immediate front tooth implant
This study looks at how the bone on the front of your upper jaw changes when a dental implant is placed right after removing a tooth that can't be saved. It may help people who need a front tooth replacement and have enough bone thickness.
CairoAges 21 years+ - NCT07476209Recruiting
Salivary gland procedure vs light therapy for dry mouth from radiation
This trial compares two treatments—a salivary gland procedure (sialendoscopy) and a light therapy (photobiomodulation)—to prevent dry mouth caused by radiation therapy for head and neck cancer. If you are about to start radiation and meet the dose limits, you may be eligible.
AlexandriaAges 18 years+ - NCT07498361Recruiting
Comparing absorbable stitches in wisdom tooth removal
This trial compares two types of dissolving stitches (sutures) used after wisdom tooth surgery to see which works better. It may help your mouth heal faster with fewer problems.
Padua, PaduaAges 18 years+ - NCT07497568Recruiting
Metformin gel for dental implant stability
This study tests whether applying a metformin gel to the implant site can help the implant stay stable and improve bone density around it. It may be a good option if you need a dental implant and have healthy enough jawbone.
Baghdad, Baghdad GovernorateAges 18–70 - NCT06075134Recruiting
EMG-guided vs. standard Botox for gummy smile treatment
This trial compares two ways of giving Botox for a gummy smile: one using a machine that measures muscle activity (EMG‑guided) and the usual method. The goal is to see which approach works better.
CairoAges 18–50 - NCT06123221Recruiting
Sinus lift study: comparing two dental implant techniques
This study compares two methods for lifting the sinus floor to place dental implants. It is for people who need an implant in the upper jaw but don't have enough bone height. The goal is to see which technique works better.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06973616Enrolling by invitation
Comparing two types of dental crowns for children's back teeth
This trial tests two different types of tooth-colored crowns for cavities in children's back baby teeth. The goal is to see which one works better and lasts longer. If your child has cavities in at least two baby molars on opposite sides of the mouth, they may be able to join.
IrbidAges 4–10 - NCT07491809Recruiting
Aesthetic dental veneers study with adhesive cementation
This trial tests different materials and methods for cementing veneers. It may help if you have healthy gums and need at least 4 veneers.
RigaAges Any age - NCT07474493Recruiting
Best ways to clean full-arch implant-supported teeth
This study compares different cleaning tools for people who have replacement teeth attached to implants across a full arch. It aims to find the easiest and most effective way to keep your new teeth clean and healthy.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07030023Enrolling by invitation
Diagnosing Wire Syndrome in people with fixed retainers
This trial looks at people who have a fixed orthodontic wire retainer to see if they have a condition called Wire Syndrome. You may be eligible if you have this retainer, are healthy, and have your dental records available.
Nice, Alpes MaritimesAges 18 years+ - NCT07693972Recruiting
Probiotic vs zinc mouthwash for bad breath and plaque in braces
This trial compares a probiotic mouthwash to a zinc and chlorhexidine mouthwash to see which is better at controlling bad breath and plaque for people with braces. It aims to find a gentler option that still works well.
Baghdad, AlkarghAges 18–30 - NCT07398898Recruiting
Can glasses and headphones reduce dental anxiety?
This study tests whether special glasses that show relaxing images and noise-cancelling headphones can help adults feel less anxious during common dental procedures like cleanings, fillings, or extractions.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT06624982Recruiting
Bone Changes After Tooth Extraction and Grafting
This study looks at how your jawbone changes after a tooth is pulled and a bone graft is put in. If you need a single tooth removed and have good general health, you may be able to join.
Milwaukee, WisconsinAges 18–75 - NCT07693946Recruiting
Jaw tracking for better implant fitting in the upper jaw
This study tests if using a special jaw tracker helps make upper-jaw implants fit better and feel more natural when you have your own lower teeth. The goal is to see if it improves your bite and overall comfort.
Al Mansurah, Dakahlia GovernorateAges 50–70 - NCT07418684Recruiting
Comparing two versus four 3D miniplates in jaw surgery
This trial compares using two custom titanium miniplates versus four to fix the upper jaw after surgery to correct jaw and teeth misalignment. The goal is to see which approach provides better stability and healing.
CairoAges 18–40
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,057 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,953 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.