Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,962 recruiting studies in this area right now.
By phase
- Not applicable1,544
- Phase 2144
- Phase 384
- Phase 182
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma74
- Periodontal Diseases50
- Dental Caries46
- Head and Neck Cancer35
- Gingivitis34
- Oral Cancer32
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Maryland21
- Massachusetts21
- Florida20
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,962 total
- NCT06640205Recruiting
New treatment for painful tooth pulp in molars
This trial tests two different materials to treat the inflamed pulp in your back teeth. It compares a special type of blood concentrate (I-PRF) with a mix of nano MTA and blood concentrate to see which is better at saving the tooth and relieving pain.
CairoAges 15–30 - NCT06642870Recruiting
Self-management programme for rare rheumatic conditions
This trial is developing a self-management programme for people with rare rheumatic conditions like lupus, vasculitis, myositis, or Sjogren syndrome. It aims to help participants better manage their condition and improve their quality of life.
BristolAges 18 years+ - NCT04981145RecruitingPhase 4
Iguratimod for Sjögren’s syndrome symptoms and safety
This trial studies whether iguratimod improves symptoms in people with primary Sjögren’s syndrome, and checks how safe it is. It focuses on people with confirmed disease markers (anti-SSA/Ro-60) and ongoing dry eyes and dry mouth.
Hangzhou, ZhejiangAges 18–70 - NCT05584566Recruiting
Bone growth treatment before dental implants: two materials compared
This study compares two bone-building products used to repair a missing “bone wall” in the jaw so dental implants can be placed. You may be able to help find which material works better for guided bone regeneration and implant readiness.
JerusalemAges 18 years+ - NCT07704151Enrolling by invitation
Zirconia crowns for damaged first permanent molars
This study compares custom-made and prefabricated zirconia crowns for children whose first permanent molars are badly damaged by cavities or a condition called molar-incisor hypomineralisation (MIH). It aims to see which type of crown works better.
IrbidAges 7–13 - NCT07702123Recruiting
Physical activity study for women with Behcet's and metabolic syndrome
This study tests if a physical activity program helps women who have both Behcet's disease and metabolic syndrome. It aims to improve their health and well-being.
Giza, DokkiAges 40–50 - NCT07698158Recruiting
Growing Well Study: healthy growth study for young children
This study looks at how children aged 6 months to 4 years grow and develop. It involves families in Leeds, Doncaster, or East London. Researchers want to understand what supports healthy growth in early childhood.
Doncaster, West YorkshireAges 6 months–4 years - NCT07703176Recruiting
Testing a new tooth filling in children's first molars
This study compares how well a newer filling material (Cention-N) works in children's permanent back teeth that have cavities. It's for healthy children ages 8 to 10 who have cavities in both lower or both upper first molars.
Minya, Asyut GovernorateAges 8–10 - NCT07702149Recruiting
Diet for Behcet's disease patients with ringing in the ears
This trial tests whether a special diet can help ringing in the ears (tinnitus) in people with Behcet's disease who also have obesity. The goal is to see if dietary changes reduce tinnitus symptoms.
Giza, DokkiAges 40–55 - NCT07703345Recruiting
Saliva markers in people with diabetes and gum disease
This study checks whether certain substances in saliva can help detect gum disease in people with type 2 diabetes. It compares the levels of these substances in people with diabetes and gum disease, people with gum disease only, people with diabetes only, and healthy volunteers.
Konya, KonyaAges 18–80 - NCT07703007Enrolling by invitation
Clear aligners for growing kids with mild underbite
This study tests whether clear aligners can fix a mild underbite in growing children aged 8 to 11. It compares how well the aligners move teeth and jaws compared to other treatments.
Al Mansurah, Dakahlia GovernorateAges 8–11 - NCT07702448Recruiting
Jaw surgery and its effect on mood and looks
This study looks at how jaw surgery affects your mood and how you feel about your appearance. You will answer questions one week before surgery and again 6 months after, and you need to use social media as part of the research.
Kirikkale, KırıkkaleAges 18–40 - NCT06652230Recruiting
Comparing two ways to place braces for a better smile
This study compares two methods of placing braces to improve smile appearance. It tests if using the natural curve of your smile works better than a standard chart for bracket positioning.
Cairo, ManialAges 11–30 - NCT06643975Recruiting
Comparing tooth implants for lower jaw overdentures
This study compares patient satisfaction and bone changes around two types of dental implants used to support a removable lower denture. It may help you understand which implant material works best for you.
CairoAges 50–60 - NCT06653868Recruiting
Sticky bone grafts for front tooth implants
This trial tests two different types of sticky bone graft materials placed around a dental implant right after a tooth is removed. It aims to see which type helps the bone heal better around the implant in the front of your mouth.
CairoAges 20–50 - NCT07693946Recruiting
Jaw tracking for better implant fitting in the upper jaw
This study tests if using a special jaw tracker helps make upper-jaw implants fit better and feel more natural when you have your own lower teeth. The goal is to see if it improves your bite and overall comfort.
Al Mansurah, Dakahlia GovernorateAges 50–70 - NCT07693972Recruiting
Probiotic vs zinc mouthwash for bad breath and plaque in braces
This trial compares a probiotic mouthwash to a zinc and chlorhexidine mouthwash to see which is better at controlling bad breath and plaque for people with braces. It aims to find a gentler option that still works well.
Baghdad, AlkarghAges 18–30 - NCT07696702Recruiting
Comparing pulp capping for deep cavities in adult back teeth
This study tests two ways to treat deep cavities that reach the nerve of the tooth, to see which helps the nerve heal better. It may be an option if you have a deep cavity in a lower molar and the nerve is still healthy.
Rohtak, HaryanaAges 18–40 - NCT07694934Recruiting
Operation Calm virtual reality study for children and teens
This study tests a virtual reality (VR) tool called Operation Calm to help children and teens feel calmer during medical, dental, or other procedures. Parents and healthcare workers also try it and share their thoughts.
MontrealAges 6 years+ - NCT07692880Recruiting
Digital vs. conventional brace bonding for teens
This trial compares a new digital method for putting braces on teeth to the usual manual method. If you need braces on both top and bottom and have all your adult teeth, this study may help improve how comfortable and fast your treatment is.
FlorenceAges 12–18 - NCT07692828Recruiting
Nutrition program for older adults with dentures
This study looks at whether a special nutritional plan (like a healthy eating program) can help older adults who wear dentures eat better and stay healthy. If you wear full dentures and are between 60 and 80, you may be able to join.
Temuco, CautínAges 60–80 - NCT07690618RecruitingPhase 1
Heat therapy for head and neck cancer
This phase 1 trial tests adding heat therapy (thermotherapy) to standard radiation (with or without chemo) for head and neck cancer. It aims to see if it is safe and effective for patients with locally advanced disease who have not had radiation before.
Rotterdam, South HollandAges 18 years+ - NCT07692061Enrolling by invitation
Speech therapy study for Cantonese-speaking kids with cleft palate
This study tests a new speech therapy program for children and teens (ages 4–17) who had cleft palate repair before age 2 and have certain speech sound errors. It aims to improve their speech clarity and communication.
Shatin, New TerritoriesAges 4–17 - NCT06651944Recruiting
Invisalign with jaw advancement aligners
This trial tests Invisalign clear aligners that also help move the lower jaw forward. It may be a good fit if you need both teeth straightening and jaw positioning help.
Richmond, British ColumbiaAges 10–16
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,962 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,741 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Genetic & congenital
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- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.