Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,962 recruiting studies in this area right now.
By phase
- Not applicable1,543
- Phase 2144
- Phase 385
- Phase 182
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma74
- Periodontal Diseases50
- Dental Caries46
- Gingivitis35
- Head and Neck Cancer35
- Oral Cancer32
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Florida21
- Maryland21
- Massachusetts21
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,962 total
- NCT06946693Recruiting
Surface smoothness and color of temporary dental crowns compared
This study compares temporary dental crowns made in three different ways: the usual method, 3D printing, and milling from a block. If you need a dental implant, this trial will see which type of temporary crown stays smooth and doesn't change color over time.
Rohtak, HaryanaAges 20–60 - NCT07180849Recruiting
New fluoride varnish vs standard varnish for braces plaque
This trial compares a new fluoride varnish that contains tiny titanium particles (nanoparticles) to a standard fluoride varnish. It tests which one is better at preventing plaque buildup for people getting braces.
IslamabadAges 16–30 - NCT07183111Recruiting
AI vs. regular instructions for braces patients
This trial compares standard instructions to AI-powered guidance (using a custom ChatGPT) to help patients with braces learn how to care for their teeth. It aims to see which method helps patients follow oral hygiene instructions better.
Islamabad, FederalAges 18–30 - NCT07177378Enrolling by invitation
Double flap closure for jaw bone damage from medication
This trial tests a surgical technique using a double tissue flap to close the jawbone in patients with medication-related osteonecrosis of the jaw (MRONJ). The goal is to improve healing and reduce complications.
TantaAges Any age - NCT07177521Recruiting
Short dental implants after tooth extraction
This study tests whether short implants placed right after a tooth is pulled are stable and work well. It may be a good option if you need a single back tooth replaced and are generally healthy.
BariAges 18–75 - NCT07180537Recruiting
Health course for joint and mood conditions
This study tests an online health course that helps improve diet and self-care to support cell health and wellbeing. It is for people with certain rheumatological conditions like rheumatoid arthritis, lupus, or psoriatic arthritis, who also have mood concerns.
Iowa City, IowaAges 18–100 - NCT07177495Recruiting
Bone graft mix for sinus lift in upper jaw
This trial tests a bone graft made of your own bone mixed with cow bone (Deproteinized Bovine Bone) to rebuild the upper jaw in the sinus area. It compares this mixed bone graft to using only cow bone for a sinus lift, helping you get implants when there is not enough bone height.
Cairo, Giza GovernorateAges 30 years+ - NCT07178301RecruitingPhase 2
Lower radiation dose for HPV-related throat cancer
This trial tests whether a lower dose of radiation to the neck is safe and effective for people with HPV-related oropharyngeal cancer. It may reduce side effects while still treating the cancer.
Chicago, IllinoisAges 18 years+ - NCT07176533Recruiting
Nerve block for pain after tonsil surgery in kids
This study tests a nerve block (a numbing injection near the cheekbone) to reduce pain after tonsil surgery in children with sleep apnea. It might help them have less pain and recover more comfortably.
London, OntarioAges 3–9 - NCT07174752Recruiting
Gum graft comparison: non-submerged vs. standard technique
This trial compares two ways to do a gum graft to increase the width of attached gum in the lower front teeth area. It tests a newer method where the graft is not covered versus the traditional covered method.
GizaAges 18 years+ - NCT07180901Recruiting
Optimizing care for head and neck cancer surgery patients
This trial uses a computer system to send reminders and tracking alerts to doctors and patients, aiming to improve care and outcomes after surgery for head and neck cancer. It may help you stay on track with your treatment plan.
Montreal, QuebecAges 18 years+ - NCT07181967Recruiting
SDF vs fluoride varnish for cavity bacteria in kids
This study compares a silver-containing liquid (SDF) to a fluoride varnish to see which works better at reducing cavity-causing bacteria in children's mouths. It may help your child if they have cavities in their baby teeth.
Asyut, Asyut GovernorateAges 3–8 - NCT07179497Recruiting
Study of Neobone in dental bone surgery
This study looks at how safe and effective Neobone is for repairing bone in dental surgery. If you need a bone graft for your jaw or teeth, this could be relevant.
LisbonAges 18 years+ - NCT07179510Recruiting
Study of a new dental bone filler for surgery patients
This study follows patients who receive a new injectable bone filler called Neocement® Inject P during dental reconstructive surgery. The goal is to see if it is safe and works well to help heal bone defects.
LisbonAges 18 years+ - NCT06778473Recruiting
Acupuncture plus self-rehab for severe Bell's palsy
This study tests whether combining a gentle type of acupuncture (intradermal acupuncture) with a self-guided rehabilitation program can help people with severe Bell's palsy recover better. It is for adults having their first episode of Bell's palsy with significant facial weakness.
Suzhou, JiangsuAges 18 years+ - NCT07166679Recruiting
Larger root canal tip for healing infection in back molars
This study tests whether making the tip of the root canal slightly larger during a single root canal treatment helps the infection heal better and reduces pain afterward. It is for people with a dead lower back molar that has an infection around the root tip.
RohtakAges 18–65 - NCT07173296Recruiting
Bleaching gel application and tooth sensitivity
This study tests two different ways of applying a gentle bleaching gel to see if one causes less tooth sensitivity. It's for people who want to whiten their front teeth and have no history of sensitivity or prior whitening.
IrbidAges 18–35 - NCT07170358Recruiting
Biomarker screening for head and neck cancer radiation therapy
This trial is looking for people with head and neck cancer who are about to start radiation therapy (possibly combined with other treatments). The goal is to find biomarkers that may help predict how well the treatment works or what side effects might occur.
Nanjing, JiangsuAges 18–75 - NCT07173491Recruiting
Music therapy for anxious dental patients having cavity treatment
This trial tests whether listening to music during a single dental visit can reduce anxiety for people with mild to moderate tooth decay who are nervous about dental procedures.
Erzurum, ErzurumAges 18–40 - NCT07166575Recruiting
Trapezius muscle changes after physiotherapy in oral cancer
This trial tests whether physical therapy can help improve shoulder muscle movement in people recently treated for oral cancer. It focuses on patients with scapular dyskinesis, a condition where the shoulder blade doesn't move properly.
TaipeiAges 20–65 - NCT07166224Recruiting
Home treatments for gum disease in older adults with memory issues
This trial tests two simple ways to improve gum health at home: using a special light-activated antibacterial rinse or using a powered toothbrush. It's for older adults who have gum disease and mild memory problems, and aims to see if these easy routines can help keep gums healthier.
Karlskrona, Blekinge CountyAges 60 years+ - NCT07167875Enrolling by invitation
Digital coaching trial to improve toothbrushing habits
This study tests if personalized coaching through a smartphone app helps people stick to better toothbrushing habits. Participants use an electric toothbrush and app for 19 weeks to see if coaching improves oral hygiene.
Petaluma, CaliforniaAges 18–80 - NCT07167394Enrolling by invitation
Virtual reality glasses for kids' dental pain relief
This trial tests whether virtual reality (VR) goggles can reduce pain during dental treatment in children aged 6 to 10 who have never been to the dentist before and have a cavity in a back tooth.
Ankara, YenimahalleAges 6–10 - NCT07169357Enrolling by invitationEarly Phase 1
Light therapy and gel for gum healing after surgery
This trial tests whether a special light treatment (photobiomodulation therapy) combined with a hyaluronic acid gel can help your gums heal better after a gum reduction procedure. It may be a good option if you have swollen gums from long-term inflammation and are looking for a way to improve healing.
BeirutAges 18–40
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,962 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,756 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Eyes & vision
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.