Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,962 recruiting studies in this area right now.
By phase
- Not applicable1,543
- Phase 2144
- Phase 385
- Phase 182
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma74
- Periodontal Diseases50
- Dental Caries46
- Gingivitis35
- Head and Neck Cancer35
- Oral Cancer32
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Florida21
- Maryland21
- Massachusetts21
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,962 total
- NCT07200297Recruiting
Comparing three mouth care methods for ICU patients on non-invasive ventilation
This study compares three different mouth care methods for patients in the intensive care unit who are using a non-invasive ventilator (a mask or mouthpiece). The goal is to find the best way to keep the mouth clean and comortable during their stay.
Erzurum, MerkezAges 18 years+ - NCT07200258Recruiting
Comparing Two Ways to Treat Gum Recession
This trial compares two surgical techniques (MCAT and VISTA) to fix receding gums on multiple teeth. It tests which method better restores gum thickness and reduces tooth sensitivity or cosmetic concerns.
MadridAges 18 years+ - NCT07195357Recruiting
Dental wear and sensitivity study for adults
This study looks at why some people have more tooth wear and sensitivity. If you are a dental clinic patient with at least 10 natural teeth, you may help researchers understand what causes these problems.
Indianapolis, IndianaAges 18 years+ - NCT07199153Recruiting
3D printed guide for precise front tooth implant placement
This study tests a new 3D printed guide that helps place a dental implant precisely in the front part of your upper jaw. If you have a single missing tooth there and good bone quality, this approach may offer a more accurate and less invasive treatment.
CairoAges Any age - NCT07195032RecruitingPhase 4
MMR vaccine safety in kids after heart transplant
This trial tests whether the MMR (measles, mumps, rubella) vaccine is safe and works well for children who have had a heart transplant. It may help protect you from these diseases if you haven't had the vaccine or no longer have immunity.
Kansas City, MissouriAges 1–17 - NCT07196566Enrolling by invitation
Double-layer closure for mouth-to-sinus hole
This trial tests a new way to close a hole between the mouth and sinus using two layers of tissue from inside the cheek and roof of the mouth. It may help people who have this problem for the first time.
TantaAges Any age - NCT07198282Recruiting
Comparing gum closure methods after wisdom tooth removal
This study compares two different ways of closing the gum after removing an impacted wisdom tooth. The goal is to see which method leads to less pain, swelling, and faster healing.
Rize, Rize ProvinceAges 18–40 - NCT07194837Recruiting
Laser treatment for root canal retreatment healing
This trial tests whether a special laser (810 nm diode) can help heal infections around the root tip after a failed root canal. It is for people who have a single-rooted tooth that needs retreatment.
CairoAges 20–45 - NCT06941636RecruitingPhase 3
Botox for jaw muscle pain from TMD
This trial tests whether Botox injections can reduce jaw and face muscle pain in people with temporomandibular disorders (TMD). It is for those who have had moderate to severe pain for at least 3 months and have not received Botox recently.
StockholmAges 18–50 - NCT06900881RecruitingPhase 2/Phase 3
Kefir Mouthwash for Healthy Gums
This clinical trial tests if a mouthwash made from kefir, a fermented milk drink, can reduce gum swelling and bleeding (gingivitis) in young adults. You might benefit if you have mild gum disease but are otherwise healthy.
BaghdadAges 18–28 - NCT05924386Recruiting
Testing dental implants for jawbone change in full dentures
This study looks at how a specific implant connection (“OT bridge attachment system”) affects changes in the lower jawbone over time in people who have no teeth. You might benefit by getting a fixed All-on-Four style set of lower teeth, with close monitoring of your jawbone and fit.
CairoAges 40 years+ - NCT07185191Recruiting
Device to treat gum shrinkage and black triangles between teeth
This trial tests a medical device (RDM36) to see if it safely and effectively treats gum shrinkage and black triangles between the front teeth, which can affect your smile.
Brescia, ItalyAges 18 years+ - NCT07188584RecruitingPhase 3
Smaller radiation vs. standard after chemo-immunotherapy for advanced nasopharyngeal cancer
This trial tests whether a smaller radiation treatment area is as effective as the usual larger one for people whose metastatic nasopharyngeal cancer has responded well to first-line chemotherapy plus immunotherapy. It aims to reduce side effects while keeping the cancer under control.
ZhuhaiAges 18–70 - NCT07191522Recruiting
Light therapy for gum disease around dental implants
This trial tests if a special light treatment (photodynamic therapy) can help treat infection and inflammation around dental implants without surgery. It may be an option for people with mild to moderate peri-implantitis who don't smoke and have healthy gums otherwise.
Almada, Monte Da CaparicaAges 18 years+ - NCT07191158Recruiting
Testing a 3D-printed molar-moving device for bite correction
This trial is testing a new 3D-printed device that moves your upper molars backward to correct a specific type of bite problem (Class II). It may help you if you have a clear overbite on both sides and your second molars are already in place.
Baghdad, Al-RussafaAges 16–30 - NCT07191262Recruiting
Comparing mouth rinses after tooth extraction and bone graft
This study compares three different mouth rinses (one with EDTA, one with chlorhexidine, and one with essential oils) after tooth extraction and bone grafting. It aims to find which rinse helps keep the area clean and promotes healing.
Birmingham, AlabamaAges 18–85 - NCT07187609Recruiting
Zinc bone graft for tooth replacement implants
This trial tests a special bone graft material made from cow bone with zinc to help support a new dental implant placed right after a tooth is removed. It may help people who need a tooth replaced in their lower jaw.
SuezAges 21–50 - NCT07191808Enrolling by invitation
Laser therapy for Bell's palsy recovery
This trial tests if low-level laser therapy can help people with Bell's palsy recover faster. It is for adults with a recent diagnosis, mild to moderate facial weakness, and no prior treatment for this episode.
FaisalābadAges Any age - NCT07192146Recruiting
Patient experiences after dental emergency treatment
This study looks at how patients feel after receiving emergency dental treatment for tooth pain. It aims to understand what factors affect their recovery and satisfaction.
BangkokAges 18 years+ - NCT07190820Enrolling by invitation
Comparing digital vs. traditional dental implant impressions
This study compares digital and traditional methods for taking dental impressions in people who have a full arch of implants supporting a permanent fixed bridge. It aims to see which method is more accurate.
ShanghaiAges 30–80 - NCT07184359Enrolling by invitation
Using social media to help dental students learn
This study tests whether using social media can help dental students learn better in their Dental Radiology course. If you are a student at UFJF's Juiz de Fora campus and use social media, you may be able to join.
Juiz de Fora, Minas GeraisAges 18 years+ - NCT06890897Recruiting
Esketamine with pulsed radiofrequency for shingles-related face pain
This trial tests whether adding esketamine (a medicine related to ketamine) to a standard nerve treatment (pulsed radiofrequency) can better relieve face pain caused by shingles. It may help if you have ongoing, moderate-to-severe pain in your face or scalp.
BeijingAges 18 years+ - NCT06947161RecruitingEarly Phase 1
Throat pack with gum spray for sore throat after surgery
This study tests whether putting a throat pack soaked in a special gum spray (Gengigel) during surgery can help prevent sore throat afterward. It is for adults having planned surgery who are in good health.
Kuala LumpurAges 18–60 - NCT06947070Recruiting
Dental implant temporary crown study
This trial tests how well 3D-printed temporary crowns for dental implants hold their color and surface smoothness. It may help you if you need a temporary crown while waiting for your permanent one.
Rohtak, HaryanaAges 20–60
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,962 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,756 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.