Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,962 recruiting studies in this area right now.
By phase
- Not applicable1,543
- Phase 2144
- Phase 385
- Phase 182
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma74
- Periodontal Diseases50
- Dental Caries46
- Gingivitis35
- Head and Neck Cancer35
- Oral Cancer32
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Florida21
- Maryland21
- Massachusetts21
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,962 total
- NCT07029360Recruiting
Coenzyme Q10 and Probiotics for Gum Health in Pregnancy
This trial tests whether adding coenzyme Q10 and probiotics to standard gum treatment can improve gum health and reduce inflammation in pregnant women. If you are in your second or third trimester and have gum concerns, this treatment may help both you and your baby.
Pavia, LombardyAges 18 years+ - NCT06207253RecruitingPhase 2/Phase 3
Testing diclofenac gel for tooth root infections
This trial tests whether a special anti-inflammatory gel (diclofenac sodium) placed inside the tooth can help treat an infection at the root tip. It is for adults with a restorable tooth and no allergies to the medication.
CairoAges 18–50 - NCT07019298Recruiting
Comparing dental filling methods for root canals
This trial studies different ways to fill a root canal after treatment to see which works best. It may help if you have a tooth with an infected or dying nerve.
Madrid, SpainAges 18 years+ - NCT07018791RecruitingPhase 3
Art-based pain test for jaw joint disorder patients
This trial tests if using art can help measure pain in people with temporomandibular joint disorders (TMD). It may offer a new way to understand and manage your pain without surgery.
Jeddah, Mecca RegionAges 18 years+ - NCT07020650Enrolling by invitation
Bone graft for preserving jawbone after tooth removal
This study tests whether a special bone graft material (carbonate apatite) helps preserve the jawbone after a tooth is removed, so you can later get a dental implant. It's for people who need a tooth pulled and are interested in getting an implant.
Ann Arbor, MichiganAges 20–80 - NCT07019428Recruiting
A new way to stabilize gum grafts with titanium tacs
This trial tests a method using small titanium tacs to hold a gum graft in place instead of stitches. It may help people with thin gum tissue around dental implants have a more comfortable and effective procedure.
CairoAges 18–40 - NCT07013682Recruiting
Platelet-rich fibrin combined with deep cleaning for gum disease
This trial tests if adding platelet-rich fibrin (a natural healing concentrate from your blood) to standard deep cleaning improves treatment for advanced gum disease. It may help patients with widespread gum disease who have not had treatment in the last year.
BernAges 18 years+ - NCT07022795Recruiting
Controlling oral habits for jaw pain relief
This trial tests behavioral techniques to help reduce harmful oral habits like teeth clenching or jaw tension, which can cause jaw pain and disorders. If you often clench or grind, this study may help you learn new habits to ease discomfort.
Toronto, OntarioAges 18 years+ - NCT07019870Recruiting
Screening for early diagnosis of nose cancer
This trial offers free screening to find nose cancer (nasopharyngeal carcinoma or NPC) early, before symptoms start. It is for people with a family history of NPC who may be at higher risk.
SingaporeAges 35–60 - NCT07018284Recruiting
Pain after root canal filling with different sealers
This study compares pain levels after root canal treatment using two different types of sealer material. It aims to find which sealer may cause less discomfort.
MadridAges 18 years+ - NCT07016555RecruitingEarly Phase 1
Mouth burning study: symptoms and management
This study looks at ways to manage the burning pain in your mouth if you have burning mouth syndrome or ongoing mouth burning without a clear cause. It tests if certain natural extracts can help ease the discomfort.
Amherst, MassachusettsAges 18 years+ - NCT07017413Recruiting
Predicting complications in maxillary sinus lift for dental implants
This study looks at what factors might lead to problems during a sinus lift procedure for dental implants in the upper jaw. It aims to help dentists better plan for patients who have less than 6mm of bone height.
Baghdad, Bab AlmodaumAges 18–70 - NCT07017062Recruiting
Study of ceramic veneers bonded with two self-adhesive dental cements
This trial compares two types of self-adhesive resin cements for bonding ceramic occlusal veneers. It aims to see which cement works better for restoring back teeth while keeping your natural tooth structure.
CairoAges 21 years+ - NCT07012915Recruiting
Study of Immune Causes of Implant Inflammation
This trial studies severe inflammation around dental implants (peri-implantitis). It aims to understand the immune and tissue changes causing this condition, which may lead to new treatment approaches.
Wroclaw, Lower Silesian VoivodeshipAges 18 years+ - NCT07011303Enrolling by invitation
Using your own blood clot to help bone heal after tooth extraction
This study tests whether placing a special clot made from your own blood (called Platelet Rich Fibrin) into the socket after a tooth extraction helps the bone heal better for a future dental implant.
Tokat ProvinceAges 18–40 - NCT07003958Recruiting
Dental sealant study for young children
This study tests different cleaning agents used before applying tooth sealants on baby molars to see which works best. It may help children without cavities keep their teeth healthy.
Tokat ProvinceAges 4–6 - NCT07011381Enrolling by invitation
Parent views on children's oral health: refugees vs Egyptians
This study looks at how parents view their child's oral health (teeth and mouth) and how it affects daily life. It compares views of Sudanese refugee parents and Egyptian parents living in Cairo.
Kafr ash Shaykh, Kafr Ash Shaikh/ ElhamrawyAges 6–12 - NCT07009015Recruiting
Oral health program for children
This study tests whether an oral health program helps improve children's knowledge and habits. It is for boys aged 10 to 11 who have their parent's permission.
Serdang, SelangorAges 10–11 - NCT07004517Recruiting
Accuracy of gum probing around dental implants
This study looks at how accurately dentists can measure the gum pocket depth around dental implants, and what factors might affect that measurement. It may help improve care for people with implants who need their crown removed for a check or repair.
Hangzhou, ZhejiangAges 18–90 - NCT07007572RecruitingPhase 2
Comparing new tooth implants with different materials
This trial compares two types of tooth implant materials for replacing a missing lower back tooth. It looks at bone health and biting strength to see which material works better.
Cairo, Cairo GovernorateAges 30–60 - NCT06235203RecruitingPhase 3
Comparing treatment timing in recurrent nasopharyngeal cancer
This trial compares giving chemotherapy and immunotherapy before surgery (neoadjuvant) versus after surgery (adjuvant) for patients whose nasopharyngeal cancer has returned locally. It aims to find which approach works better to control the cancer.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06995859Enrolling by invitation
Dental filling teaching survey for pediatric dentists
This trial asks pediatric dentistry teachers in Egypt about how they teach amalgam fillings. It is a survey study to learn about current teaching practices.
CairoAges 20 years+ - NCT06997068RecruitingPhase 2
Drug combination for returning head and neck cancer
This trial tests a combination of three drugs—methotrexate, erlotinib, and celecoxib—for people whose head and neck cancer has come back or spread. It is designed for patients in the rural Midwest who have already had or chosen not to have standard first treatment.
Rochester, MinnesotaAges 18 years+ - NCT06994754Recruiting
Expanding the upper jaw with clear aligners in cleft lip and palate patients
This trial tests whether clear aligners can safely widen the upper jaw in children with cleft lip and palate who still have some baby teeth. It may be an option for those needing jaw expansion without braces.
Cairo, SelectAges 6–12
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,962 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,756 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Eyes & vision
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.