Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,962 recruiting studies in this area right now.
By phase
- Not applicable1,543
- Phase 2144
- Phase 385
- Phase 182
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma74
- Periodontal Diseases50
- Dental Caries46
- Gingivitis35
- Head and Neck Cancer35
- Oral Cancer32
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Florida21
- Maryland21
- Massachusetts21
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,962 total
- NCT06891313Recruiting
One stage ridge splitting in the lower jaw
This trial tests two techniques for widening a narrow jawbone so dental implants can be placed, all in one surgery. It is for people who have lost at least one tooth and have a bone width between 3 and 5 mm.
CairoAges 20–48 - NCT06890988Recruiting
Dental team study to help end HIV epidemic
This trial tests if training dental teams (dentists, hygienists, assistants, navigators) can help end the HIV epidemic by offering HIV testing and prevention in dental visits. You may be able to join if you work in a dental practice that is part of this study.
New York, New YorkAges 18 years+ - NCT06897787Enrolling by invitation
Jaw surgery study: how jaw position affects joint healing
This study looks at how the way the upper jaw is positioned during corrective jaw surgery affects the joint's healing over time. It may help people with a specific type of underbite who are already planning to have both upper and lower jaw surgery.
Istanbul, FatihAges 18–65 - NCT06892496Recruiting
Healing after palate graft: comparing protection methods
This trial compares different ways to protect the roof of your mouth after a small tissue graft is taken to cover exposed roots or gum recession. It aims to find which method reduces pain and helps healing.
Richmond, VirginiaAges 18 years+ - NCT06898918Enrolling by invitation
Mothers' feeding habits and kids' eating and tooth health
This study looks at how mothers control their child's eating, how the child eats, and whether it relates to early childhood cavities. It may help families understand what affects their preschooler's dental health.
CairoAges 3–5 - NCT06892184Recruiting
How the dentist talks during numbing injections
This study tests whether the way your dentist communicates with you during a numbing shot (para-apical anesthesia) affects your pain and comfort. It may help find the best way to talk to patients during dental procedures.
Clermont-FerrandAges 18 years+ - NCT06892041Recruiting
MRI study for jaw muscle pain
This trial uses a special MRI scan to measure jaw muscle pain. It aims to better understand this condition and may help improve future treatments.
New York, New YorkAges 18–65 - NCT06895902RecruitingEarly Phase 1
Eyelid spring for closing the eye in facial paralysis
This trial tests a tiny spring placed in the eyelid to help you close your eye if it stays open due to facial nerve paralysis. It may be an option if your eye has not improved after 6 weeks.
Edmonton, AlbertaAges 18 years+ - NCT06888947Enrolling by invitation
Collagen cone for dental implants placed right after tooth removal
This study tests whether placing a collagen cone around a new dental implant helps it heal better when the implant is put in right after a tooth is pulled. It focuses on front teeth and premolars in the upper jaw.
CairoAges 30–50 - NCT06881654Enrolling by invitation
Teeth whitening with a softer tray vs. a rigid tray
This trial compares two types of trays used for at-home teeth whitening with a 16% carbamide peroxide gel: a soft tray versus a rigid tray. The goal is to see if one works better and feels more comfortable.
Alcorcón, MadridAges 18 years+ - NCT06881095Enrolling by invitation
Dental Implants with or without Socket Shield for Front Teeth
This study tests two ways to place dental implants in the front of the mouth: one using a standard technique and one that leaves a small piece of your natural tooth (the socket shield) to help preserve the gum and bone. The goal is to see which method leads to better healing and a more natural-looking result.
TantaAges 18–55 - NCT06885801Enrolling by invitationPhase 2
New Nasal Device for Kids Having Cleft Lip Surgery
This trial tests a new nasal conformer (a small device placed in the nose after surgery) to see if it helps children who are having cleft lip repair or surgery to release nasal scarring. It may improve healing and nose shape.
Knoxville, TennesseeAges Up to 18 years - NCT06885983Enrolling by invitation
Healing after gum bone repair with a collagen membrane
This trial tests how well a collagen membrane helps heal the gum and jawbone after an implant is placed. If you need a dental implant and have a small bone gap or thin bone, this study may be a good option.
BelgradeAges 18–65 - NCT06880094Recruiting
Genetic study of complex or inherited cleft lip and palate
This study uses a new genetic test called Optical Genome Mapping to look for hidden genetic causes of cleft lip or palate that are syndromic, complex, or run in families. It may help find answers for people who haven't gotten a genetic diagnosis yet.
AmiensAges Any age - NCT06811844RecruitingPhase 2
Shorter chemo plus immunotherapy for advanced nasopharyngeal cancer
This trial tests a shorter course of chemotherapy combined with an immunotherapy drug (camrelizumab) for people with advanced nasopharyngeal cancer that hasn't spread to distant organs. The goal is to see if this approach works well while reducing treatment side effects.
Xiamen, FujianAges 18–65 - NCT06808854Recruiting
Comparing two types of dental implants for a missing back tooth
This trial compares two types of dental implants (variable-thread and standard) for replacing a single missing back tooth. It aims to see which implant works better for long-term stability and healing.
DubaiAges 18 years+ - NCT06875102Recruiting
Treating fatigue in Sjögren's syndrome with auricular stimulation
This trial tests three non-medication strategies for fatigue in Sjögren's syndrome, including a type of ear stimulation. It aims to find a better way to help people who have had fatigue for at least 6 months with no clear cause.
Saint-EtienneAges 18 years+ - NCT06875440Enrolling by invitation
Green tea vs. chlorhexidine mouthwash for gum disease
This trial tests if green tea mouthwash works as well as a standard mouthwash (chlorhexidine) for treating gum inflammation. It also checks how the mouthwash affects certain cells and chemicals in your spit that are linked to gum health.
Tehran, Tehran, Iran.Ages 18–40 - NCT06877117Enrolling by invitation
Rectangular collimation study for kid's dentists
This trial tests a new way to focus x-rays (called rectangular collimation) in dental care for children. It may help reduce radiation exposure while still getting clear images.
Toronto, OntarioAges Any age - NCT06875830Recruiting
Immediate tooth replacement with mesh vs. membrane for damaged front teeth
This trial compares two materials—titanium mesh and collagen membrane—used to support a new tooth implant placed right after removing a badly decayed tooth in the upper front area. It aims to see which material works better when the bone around the tooth is partially damaged.
Cairo, Heliopolis - CairoAges 21–50 - NCT06879444Enrolling by invitation
Core strength and pelvic floor in Sjogren's
This study looks at how core stability and pelvic floor muscles work in people with primary Sjogren's syndrome. If you have this condition, the results may help doctors understand changes in muscle function.
Denizli, DenizliAges 18–65 - NCT06873932Enrolling by invitation
Studying tooth movement with special aligner attachments
This trial tests whether a new type of attachment (beveled) on clear aligners works better than standard attachments for moving teeth in adults. If you are getting aligner treatment and need certain tooth movements on both sides of your mouth, this study may help improve your results.
Curitiba, ParanáAges 18 years+ - NCT06859866Recruiting
Light therapy for gum disease around dental implants
This trial tests whether a special light treatment (photodynamic therapy) you can use at home can help reduce inflammation around dental implants (peri-implant mucositis). It's designed for people with early gum problems around implants, before they get worse.
RomaAges 18 years+ - NCT06859281RecruitingPhase 1
Safety of Grammidin throat spray in healthy adults
This trial tests the safety and how the body processes a new throat spray called Grammidin. Healthy volunteers will use the spray so researchers can see how it works and if there are any side effects.
Saint PetersburgAges 18–45
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,962 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,756 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Lungs & breathing
- Immune system & allergy
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- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.