Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,053 recruiting studies in this area right now.
By phase
- Not applicable1,631
- Phase 2148
- Phase 183
- Phase 381
- Phase 458
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma79
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Head and Neck Cancer35
- Oral Cancer35
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University53
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California40
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,053 total
- NCT06900881RecruitingPhase 2/Phase 3
Kefir Mouthwash for Healthy Gums
This clinical trial tests if a mouthwash made from kefir, a fermented milk drink, can reduce gum swelling and bleeding (gingivitis) in young adults. You might benefit if you have mild gum disease but are otherwise healthy.
BaghdadAges 18–28 - NCT06902623Recruiting
Less intense radiation for early HPV throat cancer
This study tries to see if less intense radiation can still work well for certain throat cancers linked to HPV. It is looking for people with early stage HPV-positive oropharynx cancer who may benefit from a lighter treatment plan.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06905678Recruiting
Cleft palate cost and emotion study
This study looks at how having a cleft palate affects your family's finances and emotions. You may be able to join if you are 5, 12, or 18 years old and have a cleft lip or palate.
GhentAges 4–22 - NCT06907745Recruiting
Accuracy of 3D virtual surgery planning for jaw correction
This trial tests a new digital method for planning jaw surgery that uses virtual guides instead of traditional splints. It may help make surgery more precise and reduce discomfort.
Milan, MilanAges Any age - NCT06912711RecruitingPhase 2
Chemo before and after surgery for recurrent nasal cancer
This trial tests giving chemotherapy before and after surgery for people whose nasal cancer has come back. The goal is to see if this approach helps remove the cancer more effectively and prevents it from returning again.
Guangzhou, GuangdongAges 18–65 - NCT06914596Recruiting
Comparing an at-home gum treatment to standard care after deep cleaning
This study tests if a device you use at home for 30 minutes twice a day can improve gum healing after a deep cleaning (scaling and root planing). Participants will have their gum health compared to a group that receives standard care.
Fullerton, CaliforniaAges 30–75 - NCT06914999RecruitingEarly Phase 1
Comparing a new scan to standard scan during head and neck cancer radiation
This trial is testing whether a newer type of PET/CT scan (F-18 NaF) can better detect blood vessel problems caused by radiation therapy than the standard scan (F-18 FDG) in people with head and neck cancer. If successful, it could lead to better ways to prevent and manage these complications.
Atlanta, GeorgiaAges 18 years+ - NCT06915454Recruiting
Better imaging during cancer surgery
This trial tests a high-resolution PET-CT scan done during surgery to help surgeons see exactly where the cancer ends. It may help make sure all cancer is removed while saving healthy tissue.
Nashville, TennesseeAges 18 years+ - NCT06923826RecruitingPhase 2
Study of sacituzumab govitecan for advanced salivary gland and thyroid cancers
This trial tests a drug called sacituzumab govitecan in people with advanced salivary gland cancer or thyroid cancer that has spread or cannot be removed. The goal is to see if the drug can help shrink or slow down the cancer.
SingaporeAges 21 years+ - NCT06932406Recruiting
Personality and self-help for jaw pain
This study tests whether a self-management program for jaw and face pain works differently in people with different personalities. You will learn techniques to manage your pain at home.
Valencia, ValenciaAges 18–65 - NCT06932848Recruiting
Curcumin gel for treating oral lichen planus
This trial tests if a curcumin nanogel can help heal painful sores from oral lichen planus compared to a standard corticosteroid gel. If you have this condition, you may be able to join.
BangkokAges 18 years+ - NCT06934291Recruiting
Comparing ultrasonic tools for deep gum cleaning
This trial tests two types of ultrasonic tools (piezoelectric vs magnetostrictive) for full-mouth deep gum cleaning in people with mild to moderate gum disease (periodontitis stages 1 and 2). It aims to see which tool works better for removing plaque and tartar.
Siena, SIAges 18–80 - NCT06934551Recruiting
Study on patient satisfaction after jaw surgery
This trial tests how happy patients are with their dental work after having part of the upper jaw removed (hemi-maxillectomy). It also checks how healthy the nearby teeth stay. This could help doctors pick the best way to replace missing teeth in these cases.
CairoAges 30–60 - NCT06934863Recruiting
Study of oral lichen planus and cancer risk
This study looks at people with oral lichen planus (a chronic mouth condition) to see how often it turns into mouth cancer. Researchers want to learn more about the condition and what might increase cancer risk.
RomaAges Any age - NCT06940050Recruiting
Gum graft study for lower jaw recessions
This study compares two gum grafting methods (one using a special collagen material plus soft tissue, the other using soft tissue alone) to treat multiple gum recessions on the lower jaw. It may help find a better way to cover exposed roots and improve gum health.
Ghent, Oost-VlaanderenAges 18 years+ - NCT06941636RecruitingPhase 3
Botox for jaw muscle pain from TMD
This trial tests whether Botox injections can reduce jaw and face muscle pain in people with temporomandibular disorders (TMD). It is for those who have had moderate to severe pain for at least 3 months and have not received Botox recently.
StockholmAges 18–50 - NCT06941727Recruiting
Mouth Opening and Jaw Muscle Elasticity in Oral Cancer
This study looks at how oral cancer treatment affects your ability to open your mouth and the elasticity of your jaw muscles. It may help researchers understand and prevent long-term jaw stiffness.
TaipeiAges 20–65 - NCT06944860Recruiting
3D-printed vs. traditional twin block braces for kids
This trial compares a new 3D-printed twin block brace to a traditional one for children with a large overbite (overjet ≥7 mm). It checks how well germs stick, how smooth the brace is, and how well it works—plus how children feel about it.
Kuala Lumpur, Kuala LumpurAges 10–14 - NCT06947161RecruitingEarly Phase 1
Throat pack with gum spray for sore throat after surgery
This study tests whether putting a throat pack soaked in a special gum spray (Gengigel) during surgery can help prevent sore throat afterward. It is for adults having planned surgery who are in good health.
Kuala LumpurAges 18–60 - NCT06949436RecruitingPhase 2
Early Gamma Knife for Trigeminal Neuralgia
This study tests if giving Gamma Knife radiosurgery (a precise beam of radiation) early after diagnosis can help control facial pain from trigeminal neuralgia. It is for people who have not yet tried many medications or are satisfied with their current pain control.
Edmonton, AlbertaAges 18 years+ - NCT06957652Recruiting
Surgery for advanced gum disease around dental implants
This study tests a surgical technique to repair bone damage around dental implants caused by severe gum disease (peri-implantitis). It is designed for people with specific types of bone defects and healthy gums elsewhere in the mouth.
Ankara, TurkeyAges 18–75 - NCT06958874Recruiting
Erythritol for gum pocket healing
This study tests if adding erythritol to standard gum treatment helps close deep gum pockets in people with advanced gum disease (periodontitis).
L’AquilaAges 35 years+ - NCT06960070Recruiting
Comparing different types of resin fillings for root‑canal‑treated molars
This study compares two types of resin onlays (custom‑made fillings) to see which works better for molars that have had a root canal. If you have a back tooth with a root canal and a cavity on the top and one side, this trial may help decide the best repair.
Mersin, MersinAges 18–84 - NCT06961409Recruiting
Saliva markers test for gum health
This trial measures certain proteins in your saliva to understand how they relate to different stages of gum disease. If you're generally healthy and have not smoked or taken certain medications recently, you may be able to join and help researchers learn more about gum health.
Izmir, ÇiğliAges 18–70
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,053 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,969 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.