Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,053 recruiting studies in this area right now.
By phase
- Not applicable1,631
- Phase 2148
- Phase 183
- Phase 381
- Phase 458
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma79
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Head and Neck Cancer35
- Oral Cancer35
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University53
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California40
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,053 total
- NCT07110948Enrolling by invitation
Long-term follow-up of tongue-tie surgery in children
This study follows infants who had tongue-tie surgery (frenectomy) to see how they are doing as they grow up. Parents will bring their child to a clinic once a year and take photos of their child's tongue.
EdmontonAges 1 day–1 year - NCT07110220Enrolling by invitation
How well do ceramic dental restorations hold up over time?
This study looks at how well ceramic dental restorations (like crowns and bridges) have lasted over time. If you've had one placed at the University Hospital of Liège, your experience could help dentists understand how to improve future treatments.
LiègeAges Any age - NCT07102121Enrolling by invitation
Comparing tooth sensitivity after cementing crowns with two dental materials
This study tests whether one type of dental cement causes less tooth sensitivity than another after placing a crown. The results could help your dentist choose the material that feels better for you.
Mingora, Khyber PakhtunkhwaAges 15–60 - NCT07095374Enrolling by invitation
How jaw widening affects premolar tilt
This study looks at how widening the upper jaw with a special device (rapid palatal expander) affects the tilt of certain teeth (premolars). It may help doctors understand how to plan better orthodontic treatments.
Pavia, LombardyAges 6–14 - NCT07090772Enrolling by invitation
Comparing jaw position methods for splint therapy in TMJ disc displacement
This trial tests different ways to determine the best jaw position for a mouth splint used to treat a specific type of temporomandibular joint (TMJ) problem where the disc is out of place and doesn't go back. The goal is to see which method works better for reducing pain and improving jaw function.
Fuzhou, FujianAges 13–50 - NCT07090694Enrolling by invitationPhase 1
Sinus lift with or without platelet-rich fibrin for dental implants
This trial compares two ways to place dental implants in the upper jaw where there is not enough bone: one uses a special clotting substance (PRF) and the other does not. The goal is to see which method works better.
RiyadhAges 25–65 - NCT07088809Enrolling by invitation
Nanoparticles with Platelet-Rich Fibrin for Gum Recession
This trial tests a new material to treat gum recession—tiny particles mixed with your own blood components (platelet-rich fibrin) placed as a membrane. The goal is to see if it helps cover exposed roots and improve gum health.
Tanta, Gharbia GovernorateAges 20–45 - NCT07062757Enrolling by invitation
Massage and melatonin for jaw surgery recovery
This study tests whether combining gentle lymphatic drainage massage with melatonin can reduce pain and swelling after jaw surgery. If you are scheduled for jaw surgery for the first time and are otherwise healthy, you may be able to join.
Istanbul, FatihAges 16–55 - NCT07028151Enrolling by invitation
Massage versus standard care for teeth grinding
This study tests whether a classical massage can help relieve jaw tension and other symptoms of teeth grinding (bruxism) in college students, compared to standard treatments. If you grind or clench your teeth and are between 18 and 27, this might be a non-invasive option to explore.
Bartın, AnkaraAges 18–27 - NCT07011381Enrolling by invitation
Parent views on children's oral health: refugees vs Egyptians
This study looks at how parents view their child's oral health (teeth and mouth) and how it affects daily life. It compares views of Sudanese refugee parents and Egyptian parents living in Cairo.
Kafr ash Shaykh, Kafr Ash Shaikh/ ElhamrawyAges 6–12 - NCT07011303Enrolling by invitation
Using your own blood clot to help bone heal after tooth extraction
This study tests whether placing a special clot made from your own blood (called Platelet Rich Fibrin) into the socket after a tooth extraction helps the bone heal better for a future dental implant.
Tokat ProvinceAges 18–40 - NCT06991998Enrolling by invitation
Comparing tooth graft vs. bone graft for gum disease bone defects
This trial tests whether a graft made from your own extracted tooth works as well as a traditional bone graft, both combined with a special enamel protein, to repair bone loss from gum disease.
Budapest, BudapestAges 18 years+ - NCT06984666Enrolling by invitation
Study of facial profiles at 45 degrees
This study looks at facial features from a 45-degree angle to see what makes a beautiful profile. It includes orthodontists, patients who have had braces for over a year, and adults without braces experience. You will have photos taken and answer some questions.
Fuzhou, FujianAges 18–50 - NCT06980714Enrolling by invitation
Electric vs. manual toothbrush for advanced gum disease
This study compares electric and manual toothbrushes to see which one works better for people with advanced gum disease (stage 3 or 4 periodontitis). It might help you find a more effective way to care for your teeth and gums at home.
L’AquilaAges 18 years+ - NCT06976749Enrolling by invitation
Jaw appliances for overbite and airway in teens
This trial compares two dental appliances—Twin Block and Myobrace—to see which one better improves your airway and facial shape during the teenage growth spurt. If you have a set-back lower jaw and moderate overbite, participating could help guide your jaw growth and breathing.
BaghdadAges 10–14 - NCT06967649Enrolling by invitation
Dental implant healing and success over 5 years
This study will check how well dental implants heal and stay healthy over 5 years. It uses implants made by SIN Implant System. The goal is to see if the implant bonds well with your bone and if the gums around it stay healthy.
Niterói, Rio de JaneiroAges 18 years+ - NCT06959602Enrolling by invitation
Comparing two root canal cleaning methods for infected teeth
This trial compares two ways of cleaning infected root canals during a root canal procedure. The goal is to see which method better removes bacteria and improves healing.
AthensAges 18–80 - NCT06958445Enrolling by invitationPhase 2
Preventing mouth sores during breast cancer radiation
This trial tests whether a natural alginate treatment can reduce painful mouth sores and improve quality of life for women with breast cancer who are receiving radiation after surgery. If you are getting radiation to the breast area and have lymph node involvement, this treatment may help you feel better during therapy.
TaipeiAges 18 years+ - NCT06934317Enrolling by invitation
Bite force after root canal treatment vs. regenerative therapy
This trial compares how strongly you can bite down on a tooth that has had a root canal or a newer regenerative treatment. It is for people with a dead nerve inside a permanent tooth who are otherwise healthy.
IrbidAges 10–60 - NCT06929676Enrolling by invitation
Tooth mobility after gum disease treatment and splinting
This trial tests how much tooth movement improves after deep cleaning and splinting (connecting loose teeth) in people with advanced gum disease. It may help if you have loose front teeth from gum disease.
Piracicaba, São PauloAges 18 years+ - NCT06926322Enrolling by invitation
Treating dead baby molars with special medicines
This study tests different medicines to treat dead (necrotic) baby molars in children. The goal is to safely clean the infection and save the tooth so it can stay until it falls out naturally.
CairoAges 4–8 - NCT06912438Enrolling by invitation
Emotional release after dry needling for jaw and head pain
This study tests whether a dry needling technique (trigger point needling) can help release emotional tension and reduce pain from muscle knots in the head and neck. It may be a good option if you have jaw or headache pain related to muscle tightness.
Tel Aviv, IsraelAges 18 years+ - NCT06897787Enrolling by invitation
Jaw surgery study: how jaw position affects joint healing
This study looks at how the way the upper jaw is positioned during corrective jaw surgery affects the joint's healing over time. It may help people with a specific type of underbite who are already planning to have both upper and lower jaw surgery.
Istanbul, FatihAges 18–65 - NCT06881654Enrolling by invitation
Teeth whitening with a softer tray vs. a rigid tray
This trial compares two types of trays used for at-home teeth whitening with a 16% carbamide peroxide gel: a soft tray versus a rigid tray. The goal is to see if one works better and feels more comfortable.
Alcorcón, MadridAges 18 years+
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,053 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,969 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.