Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,053 recruiting studies in this area right now.
By phase
- Not applicable1,631
- Phase 2148
- Phase 183
- Phase 381
- Phase 458
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma79
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Head and Neck Cancer35
- Oral Cancer35
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University53
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California40
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,053 total
- NCT07424820Enrolling by invitation
Magnetic mallet vs. drilling for dental implants in soft jawbone
This trial compares two techniques for placing dental implants in the upper jaw where the bone is very soft (type D4). It tests whether a magnetic mallet (a tool that uses gentle taps) is better than conventional drilling for placing implants in this challenging bone type.
Mosul, MosulAges 20–60 - NCT07383350Enrolling by invitation
Information sheets for better communication on antibiotics
This study tests if using simple information sheets helps you and your doctor talk better about infections like sore throat, sinusitis, or bronchitis, and make wise decisions about antibiotics — so you only get them when truly needed.
AalborgAges 18 years+ - NCT07367737Enrolling by invitation
Comparing histatin-1 levels in smokers and non-smokers with gum disease
This study looks at a protein called histatin-1 in your saliva to see how it changes with gum disease treatment. Researchers want to compare levels between smokers and non-smokers before and after deep cleaning (a non-surgical treatment for periodontitis). It may help understand how smoking affects gum healing.
Baghdad, Medical CityAges Any age - NCT07363031Enrolling by invitationPhase 2
Valacyclovir for mouth sores during head and neck radiation
This trial tests whether the antiviral drug valacyclovir can prevent or reduce painful mouth sores caused by radiation therapy for head and neck cancer.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT07359937Enrolling by invitation
Reducing fluoride risk in school children
This trial tests a program to lower children's exposure to fluoride in drinking water. It includes education and urine tests to measure fluoride levels. Families with kids in kindergarten who get meals at school may benefit.
PalermoAges 2–5 - NCT07350343Enrolling by invitation
Comparing 3D-printed vs thermofit clear aligners
This study compares two ways of making clear plastic aligners to straighten teeth. It looks at whether directly 3D-printed aligners work better than ones made by pressing a plastic sheet over a 3D model. This could be for people with mild to moderate teeth alignment issues.
KarbalaAges 16–40 - NCT07345351Enrolling by invitation
Pilates vs. lifestyle advice for jaw muscle pain
This study compares two non-drug treatments for jaw muscle pain: clinical Pilates vs. lifestyle counseling. It aims to see which approach better reduces pain and improves jaw function in women.
Antakya, HatayAges 18–45 - NCT07327333Enrolling by invitation
AR education for nurses on oral mucositis care
This trial tests if an augmented reality (AR) learning tool helps nurses better care for patients with oral mucositis, a painful side effect of cancer treatment. It is designed for cancer nurses at a hospital in northern Taiwan.
TaipeiAges 20 years+ - NCT07324928Enrolling by invitation
Pulpotomy treatment for baby teeth using iron sulfate or MTA
This study compares two materials (iron sulfate and a special cement called MTA) used during a pulpotomy—a procedure to treat cavities in baby molars when the nerve is exposed. It aims to find which material works better to keep the tooth healthy until it falls out naturally.
Jizan, Jazan RegionAges 6–10 - NCT07316582Enrolling by invitationPhase 4
Melatonin gel for gum disease treatment
This trial tests a new gel made with melatonin and platelet-rich fibrin to treat gum disease. It may help reduce pocket depth and improve gum health without surgery.
New CairoAges 20–60 - NCT07309588Enrolling by invitationPhase 1/Phase 2
Hyaluronic acid gel for dry mouth
This trial tests if a gel made from hyaluronic acid (a natural substance that holds moisture) can help people with long-term dry mouth. It aims to make eating, speaking, and sleeping easier.
Poznan, Greater Poland VoivodeshipAges 38–78 - NCT07266701Enrolling by invitation
Bite Force Test for Better Treatment Plans
This trial studies a simple bite force test to help doctors assess risks and create personalized treatment plans. It is for adults who can understand Swedish.
Malmö, Skåne CountyAges 18 years+ - NCT07264218Enrolling by invitation
Helping burn survivors with a tight mouth using a custom 3D-printed brace
This study tests a custom-made mouth brace created from a 3D scan of your mouth. The brace may help stretch and improve the opening of a tight mouth caused by burn scars, making daily activities like eating and speaking easier.
SeoulAges 18 years+ - NCT07262086Enrolling by invitation
Bioactive filling for deep cavities in back teeth
This trial tests a new type of self-hardening tooth-colored filling material that may help repair and protect deep cavities in back teeth. It is looking for people with two molars that need deep fillings, to see if the material stays strong and helpful over time.
Ismailia, IsmaliaAges 21–45 - NCT07233512Enrolling by invitation
Periodontal treatment for Alzheimer's disease
This trial tests whether treating gum disease can improve outcomes for people with Alzheimer's disease. If you have mild to moderate Alzheimer's and gum disease, you may be able to join.
LiègeAges Any age - NCT07196566Enrolling by invitation
Double-layer closure for mouth-to-sinus hole
This trial tests a new way to close a hole between the mouth and sinus using two layers of tissue from inside the cheek and roof of the mouth. It may help people who have this problem for the first time.
TantaAges Any age - NCT07191808Enrolling by invitation
Laser therapy for Bell's palsy recovery
This trial tests if low-level laser therapy can help people with Bell's palsy recover faster. It is for adults with a recent diagnosis, mild to moderate facial weakness, and no prior treatment for this episode.
FaisalābadAges Any age - NCT07190820Enrolling by invitation
Comparing digital vs. traditional dental implant impressions
This study compares digital and traditional methods for taking dental impressions in people who have a full arch of implants supporting a permanent fixed bridge. It aims to see which method is more accurate.
ShanghaiAges 30–80 - NCT07169357Enrolling by invitationEarly Phase 1
Light therapy and gel for gum healing after surgery
This trial tests whether a special light treatment (photobiomodulation therapy) combined with a hyaluronic acid gel can help your gums heal better after a gum reduction procedure. It may be a good option if you have swollen gums from long-term inflammation and are looking for a way to improve healing.
BeirutAges 18–40 - NCT07167875Enrolling by invitation
Digital coaching trial to improve toothbrushing habits
This study tests if personalized coaching through a smartphone app helps people stick to better toothbrushing habits. Participants use an electric toothbrush and app for 19 weeks to see if coaching improves oral hygiene.
Petaluma, CaliforniaAges 18–80 - NCT07167394Enrolling by invitation
Virtual reality glasses for kids' dental pain relief
This trial tests whether virtual reality (VR) goggles can reduce pain during dental treatment in children aged 6 to 10 who have never been to the dentist before and have a cavity in a back tooth.
Ankara, YenimahalleAges 6–10 - NCT07142629Enrolling by invitation
Cavity removal methods for MIH-affected molars
This trial compares two ways of removing tooth decay in children with a condition called MIH (which makes enamel weak and spotted). It tests whether selective or non-selective drilling works better for deep cavities, aiming to save the tooth and keep the nerve healthy.
IrbidAges 6–13 - NCT07136155Enrolling by invitation
Two ways to treat deep cavities in baby teeth
This study compares two ways to treat deep cavities in baby (primary) molars. One method places a special soothing medicine under a filling; the other uses a metal crown that covers the whole tooth. Both aim to keep the tooth healthy without needing a nerve treatment or extraction.
IrbidAges 4–9 - NCT07129096Enrolling by invitation
Digital relaxation training for jaw pain
This study tests if a digital relaxation program can help reduce jaw pain caused by temporomandibular disorders (TMD). It may be a good option if you have jaw muscle or joint pain and want to try a non-drug approach.
OuluAges Any age
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,053 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,969 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.