Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,053 recruiting studies in this area right now.
By phase
- Not applicable1,631
- Phase 2148
- Phase 183
- Phase 381
- Phase 458
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma79
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Head and Neck Cancer35
- Oral Cancer35
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University53
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California40
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,053 total
- NCT06879444Enrolling by invitation
Core strength and pelvic floor in Sjogren's
This study looks at how core stability and pelvic floor muscles work in people with primary Sjogren's syndrome. If you have this condition, the results may help doctors understand changes in muscle function.
Denizli, DenizliAges 18–65 - NCT06875440Enrolling by invitation
Green tea vs. chlorhexidine mouthwash for gum disease
This trial tests if green tea mouthwash works as well as a standard mouthwash (chlorhexidine) for treating gum inflammation. It also checks how the mouthwash affects certain cells and chemicals in your spit that are linked to gum health.
Tehran, Tehran, Iran.Ages 18–40 - NCT06873932Enrolling by invitation
Studying tooth movement with special aligner attachments
This trial tests whether a new type of attachment (beveled) on clear aligners works better than standard attachments for moving teeth in adults. If you are getting aligner treatment and need certain tooth movements on both sides of your mouth, this study may help improve your results.
Curitiba, ParanáAges 18 years+ - NCT06863103Enrolling by invitation
Treating children with major dental needs
This study explores how dentists and dental specialists treat children who need a lot of dental work. It aims to improve care for kids with extensive dental needs.
MalmöAges Up to 65 years - NCT06850857Enrolling by invitation
Validating IMPACT for facial injury recovery
This trial is testing a tool (IMPACT) to better understand recovery after facial injuries. If you recently had a broken facial bone or soft tissue injury to your face, this study could help improve care for others like you.
Sacramento, CaliforniaAges 18 years+ - NCT06837779Enrolling by invitation
Study for treating sensitive teeth with fluoride and mineral boosters
This trial tests if applying fluoride using a mild electric current (iontophoresis) with other minerals can reduce pain in sensitive tooth roots. It may be an option if you have at least four sensitive back teeth.
Cairo, Cairo GovernorateAges 35–60 - NCT06831487Enrolling by invitation
Gum disease imaging study with new microscope
This study uses a new type of imaging (like an advanced microscope) to look at gum tissue in people with healthy gums, gingivitis, or periodontitis. It aims to see if the imaging can tell the difference and help with diagnosis.
Catania, ItalyAges 18–75 - NCT06826391Enrolling by invitation
Can a filler injection treat gum recession and tooth sensitivity?
This study tests a special injectable filler (calcium hydroxylapatite) to see if it can help grow back gums that have receded and reduce tooth sensitivity. It is for people with mild to moderate gum recession who are in good health.
South Euclid, OhioAges 20–70 - NCT06810752Enrolling by invitationPhase 1/Phase 2
Thyme honey for mouth lichen planus
This trial tests whether thyme honey can help manage oral lichen planus, a condition causing white patches or sores in the mouth. Participants will apply the honey to the affected areas.
CairoAges Any age - NCT06798116Enrolling by invitation
Gum disease treatment with platelet-rich fibrin and albumin gel
This study tests a new treatment for severe gum disease. It combines a natural blood product (platelet-rich fibrin) with a special albumin gel to help repair bone defects around teeth. The goal is to see if this mixture helps the bone grow back better than standard treatment.
Al MansurahAges 25–55 - NCT06791694Enrolling by invitation
Comparing tooth color measurement methods for dental students
This trial tests different ways to measure tooth color in healthy young adults. It aims to see which method works best for dental students to learn.
Altındağ, AnkaraAges 18–40 - NCT06782087Enrolling by invitationPhase 1
Laser vs. nano-chitosan gel for whitening dead teeth
This study tests two methods to whiten teeth that have had root canal treatment. It compares using a diode laser with a special gel to see which works better for lightening discolored front teeth.
Giza, EgyptAges 18–40 - NCT06775717Enrolling by invitation
Mirror and imagination exercises for Bell's palsy recovery
This study tests whether practicing facial movements in your imagination (motor imagery) combined with mirror exercises can help reduce unwanted facial movements (synkinesis) and improve facial symmetry and quality of life in people with new Bell's palsy. You would learn simple exercises to do at home with a mirror and guidance.
Sialkot, Punjab ProvinceAges 18 years+ - NCT06773923Enrolling by invitationPhase 3
3D-printed bone scaffold trial for dental implants
This trial tests a 3D-printed scaffold that dissolves over time to help regrow jawbone for dental implants. It is for people in Valdivia, Chile, who need bone buildup in the lower jaw.
ValdiviaAges 30–70 - NCT06763640Enrolling by invitation
TILs as a predictor in nasopharyngeal cancer
This study looks at how immune cells called TILs (tumor-infiltrating lymphocytes) in your tumor tissue might predict outcomes for nasopharyngeal cancer. It may help doctors better understand your cancer and guide future treatment decisions.
Nanchang, JiangxiAges 18–70 - NCT06761521Enrolling by invitation
Monitoring implant health with aMMP-8 test
This study uses a special test to check for inflammation around dental implants. It may help catch problems early and is for people who already have implants.
Helsinki, UusimaaAges Any age - NCT06726902Enrolling by invitation
Comparing air polishing powders for gum disease treatment
This trial tests whether different air polishing powders improve nonsurgical gum disease treatment in people with moderate to severe periodontitis. It aims to find a better way to clean below the gum line without surgery.
AlexandriaAges 30–65 - NCT06725095Enrolling by invitation
Enamel gel for gum inflammation around dental implants
This study tests whether a special enamel gel can reduce inflammation around dental implants. It might help if your implant has bleeding gums but no deeper infection.
Catania, CtAges 18–75 - NCT06724497Enrolling by invitationPhase 1/Phase 2
Comparing 3D face scan methods for jaw surgery patients
This trial tests whether using a handheld 3D scanner is as accurate as a standard optical scanner for predicting soft tissue changes after corrective jaw surgery. It aims to find a more convenient and accessible way to plan surgery for patients with an underbite.
Cairo, Giza GovernorateAges 18–50 - NCT06699654Enrolling by invitation
Spirulina gel for gum disease treatment
This trial tests if a gel made from spirulina can help treat mild-to-moderate gum disease (periodontitis). You may be a good fit if your gum disease is at a specific stage and you are otherwise healthy.
El-Sheikh Zayed City, Cairo GovernorateAges Any age - NCT06697574Enrolling by invitation
Hypnotherapy for oral lichen planus
This trial tests whether hypnosis can help manage oral lichen planus (OLP), a chronic mouth condition. You will be randomly assigned to either hypnotherapy or a session explaining how your mind and immune system interact. Your symptoms will be checked after 2, 6, and 12 weeks.
Tel AvivAges 18 years+ - NCT06688175Enrolling by invitationPhase 2
Combining IMRT and lobaplatin chemo for nasopharyngeal cancer
This trial tests whether combining a newer chemotherapy drug (lobaplatin) with standard radiation and chemotherapy is safe and effective for adults aged 65 to 80 with a certain type of nasopharyngeal cancer that hasn't spread to distant organs.
Xiamen, FujianAges 65–80 - NCT06636097Enrolling by invitation
Dental implant bridge inner surface study
This study looks at the inside surface of full-arch dental bridges that are screwed into implants. It aims to understand how this surface affects the health of the surrounding gums and bone.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06633640Enrolling by invitationEarly Phase 1
Algae bone graft for gum disease bone defects
This study tests a new bone graft material made from algae, used with a collagen membrane, to help repair bone damage caused by gum disease. It might be an option if you have a deep pocket in the bone around a tooth and are healthy enough for the procedure.
CairoAges 20–65
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,053 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,969 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.