Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,575 recruiting studies in this area right now.
By phase
- Not applicable2,950
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University20
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas51
- Illinois40
- North Carolina40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,575 total
- NCT07834151Recruiting
Kinetic chain training plus standard exercises for shoulder pain
This study tests whether adding kinetic chain training (exercises that involve the whole body, like the legs and core) to standard shoulder exercises helps reduce shoulder pain and improve movement in people with subacromial pain syndrome, a common cause of shoulder pain.
Islamabad, Punjab ProvinceAges 35–60 - NCT07838558Recruiting
Comparing two muscle-relaxing exercises for lower back pain
This study compares two muscle-relaxing techniques to help people with lower cross syndrome, a common cause of low back pain and poor posture. If you join, you'll receive one of these physiotherapy approaches to see which works better for relieving your pain.
Islamabad, Punjab ProvinceAges 19–35 - NCT07838324Recruiting
Pain reprocessing therapy for functional dyspepsia
This study tests a type of talk therapy called Pain Reprocessing Therapy (PRT) to see if it helps reduce stomach pain and discomfort in people with functional dyspepsia. The therapy aims to retrain the brain's response to pain signals, potentially easing symptoms.
Rochester, MinnesotaAges 18 years+ - NCT07840183RecruitingPhase 4
Epidural versus other pain relief for open ventral hernia repair
This study compares two ways to manage pain after hernia repair surgery: using an epidural (a small tube in your back that delivers pain medicine) versus other pain medications that aim to reduce opioid use. The goal is to see which method provides better pain relief and helps you recover more comfortably.
Chicago, IllinoisAges 18–80 - NCT07837102Recruiting
Mobile app for monitoring chronic pain
This study tests a mobile app that helps you manage chronic pain by monitoring your symptoms from home. If you have chronic pain syndrome (including fibromyalgia) and a smartphone, this trial might help you track your pain and stay connected with your care team.
Hackensack, New JerseyAges 18 years+ - NCT07839195Enrolling by invitationPhase 2
Steroid injection after radiofrequency ablation for back and neck pain
This trial tests whether giving a corticosteroid injection right after a radiofrequency nerve ablation (a procedure that zaps nerve endings to reduce pain) can help prevent the temporary nerve irritation that sometimes happens after. It may help make your recovery more comfortable.
BangkokAges 18 years+ - NCT07841405Recruiting
Heat therapy for chronic sciatica
This study tests a type of physiotherapy called TECAR (a kind of heat therapy) to see if it helps reduce sciatic pain caused by a disc problem. If you've had this pain for more than 3 months, this treatment might offer relief without surgery.
GizaAges 35–50 - NCT07841652Enrolling by invitation
Exercise therapy for shoulder blade movement problems
This study compares two types of shoulder exercises to see which works better for people with shoulder blade movement problems, often caused by lots of desk work. If you join, you'll do a guided exercise program that may reduce pain and improve your shoulder function.
Lahore, Punjab ProvinceAges 20–55 - NCT07830446Recruiting
Pain relief injections for breast surgery
This trial tests whether a special numbing injection (called a fascial plane block) given before breast surgery can reduce pain after the operation. It compares this to standard pain management to see if it helps you recover with less discomfort.
BursaAges 18–80 - NCT07832552Enrolling by invitationPhase 3
Eye drop treatment for pain and swelling after cataract surgery
This study tests a medication given as an injection during cataract surgery to prevent eye pain and swelling. It aims to see if it helps you recover more comfortably.
Kansas City, MissouriAges 18 years+ - NCT06160778RecruitingPhase 3
Comparing two pain medicines for kids with belly pain
This study compares two common pain relievers—ketorolac and morphine—given through an IV to children with acute abdominal pain. It aims to find which works better and has fewer side effects for this condition.
Calgary, AlbertaAges 6–17 - NCT07832929Recruiting
Alcohol injection for cervical disc herniation pain
This study tests a procedure where a special alcohol gel is injected into a damaged disc in the neck to relieve pain. It is for people with neck pain caused by a disc problem that has not improved with other treatments.
Vimercate, Monza E BrianzaAges 18–75 - NCT07832188Recruiting
Brain stimulation for chronic lower back pain
This study tests a non-invasive brain stimulation technique that uses gentle electrical currents to target the part of the brain involved in pain processing. It may help reduce chronic lower back pain that is not caused by a specific injury or condition.
Jinan, ShandongAges 18–80 - NCT07831278Recruiting
Training muscle signals after amputation or nerve surgery
This study tests a new training program to help your brain and muscles work together after an amputation or nerve surgery. It may improve how you move and feel after surgery.
Boston, MassachusettsAges 18–65 - NCT07827664Recruiting
How insomnia affects muscle pain from exercise
This study looks at how insomnia affects pain sensitivity and how much muscle pain people feel after exercise. It may help researchers understand the link between sleep and pain, which could lead to better treatments for people with insomnia.
Hong KongAges 18–60 - NCT07829289Enrolling by invitation
Ear acupressure for long-term back pain in postmenopausal women
This study tests whether applying pressure to specific points on the ear can reduce chronic low back pain in women who have gone through menopause. You would receive a simple, non-invasive treatment that you can do at home.
Kaohsiung City, Sanmin DistrictAges 50–65 - NCT07833280Recruiting
Pelvic pain, movement, sleep, and quality of life in women
This study looks at how chronic pelvic pain affects movement, sleep, and daily life in women. It may help find better ways to support women with this condition.
Kırşehir, MerkezAges 18–65 - NCT07832318Recruiting
Herbal injection for chronic sciatica
This trial tests whether an herbal injection into acupuncture points can safely reduce leg pain from sciatica that has lasted more than 3 months. It compares this treatment to usual care, and may offer a new option for people who haven't found relief.
Bucheon-si, Gyeonggi-doAges 19–70 - NCT07827625Recruiting
Comparing two physical therapies for ankle pain in type 2 diabetes
This study tests whether a specific hands-on therapy (Mulligan mobilization) improves ankle motion, pain, and quality of life better than standard physical therapy in people with type 2 diabetes who have ankle stiffness and pain.
Islamabad, FederalAges 50–70 - NCT07831096Recruiting
Nerve block comparison for shoulder surgery pain relief
This study compares two types of nerve blocks to see which one provides better pain relief after outpatient shoulder surgery. Participants will receive one of the two blocks, and the study will track their pain and recovery.
Varese, ItalyAges 18 years+ - NCT07826546Recruiting
Back pain sensitivity as a predictor of recovery
This study looks at whether increased sensitivity to pain in people with chronic low back pain might predict how well they recover. It aims to help doctors understand which treatments might work best for each person.
MardinAges 18–65 - NCT07827677Recruiting
Brain stimulation for muscle pain relief in people with insomnia
This study looks at whether different types of brain stimulation (called TMS) can help reduce the muscle pain triggered during a test. It is designed for people who also have insomnia, and who are otherwise healthy.
Hong KongAges 18–60 - NCT07826741Recruiting
Pain relief options for open inguinal hernia surgery
This study compares two ways to manage pain after open inguinal hernia repair: a spinal injection of morphine and a numbing injection near the abdomen. The goal is to find which method provides better pain relief with fewer side effects.
Yenimahalle, AnkaraAges 18–80 - NCT07833930Recruiting
Breakthrough pain after arm numbing block in diabetic patients
This study looks at whether people with diabetes have more breakthrough pain (pain that breaks through despite the block) within 48 hours after an arm surgery with a specific type of nerve block. The goal is to understand and improve pain management for diabetic patients.
TaiyuanAges 18–80
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,575 recruiting pain medicine studies from the U.S. registry right now, out of 6,452 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.