Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,575 recruiting studies in this area right now.
By phase
- Not applicable2,950
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University20
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas51
- Illinois40
- North Carolina40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,575 total
- NCT07826650Recruiting
How acute pain affects sleep in people with insomnia
This study looks at how a short-term (acute) pain affects sleep quality in people who suffer from insomnia compared to healthy sleepers. Participation may help researchers understand the link between pain and sleep problems.
Hong KongAges 18–60 - NCT07826936RecruitingEarly Phase 1
Nerve block for severe abdominal pain in the emergency department
This trial tests whether a nerve block can provide better pain relief for severe abdominal pain that hasn't improved with standard pain medicine. It's for people who are not candidates for surgery and are in the emergency department or already in the hospital.
Orange, CaliforniaAges 18 years+ - NCT07831096Recruiting
Nerve block comparison for shoulder surgery pain relief
This study compares two types of nerve blocks to see which one provides better pain relief after outpatient shoulder surgery. Participants will receive one of the two blocks, and the study will track their pain and recovery.
Varese, ItalyAges 18 years+ - NCT07824466Recruiting
Nerve block for pain after shoulder fracture surgery
This study tests a type of numbing injection (nerve block) given before shoulder surgery to control pain while keeping your arm muscles strong. It aims to reduce pain after surgery without making your arm feel weak.
Shibīn al Kawm, MenoufiaAges 18–70 - NCT07824323RecruitingPhase 4
Early cholesterol treatment after a heart attack
This study tests whether adding an extra cholesterol-lowering drug (bempedoic acid) to the usual treatment soon after a heart attack or related event can lower 'bad' cholesterol more effectively. It may help reduce the risk of future heart problems.
Taipei, Taipei CityAges 18 years+ - NCT07820293Recruiting
Comparing two massage techniques for upper back muscle pain
This study compares two hands-on treatments for trapezius myalgia, a condition causing neck and upper back pain. The goal is to see which technique provides better relief for people with this type of muscle pain.
IslamabadAges 18–45 - NCT07818980Recruiting
An online pain management program for Canadian veterans
This study is testing an online pain management program designed for Canadian veterans. If you have chronic pain, joining could help you learn ways to manage pain from home.
Toronto, OntarioAges 18–80 - NCT07818954Recruiting
Nerve block near the belly for gallbladder surgery
This study tests a numbing injection (called a subcostal TAP block) given near the belly to see if it affects brain activity during gallbladder surgery. It may help improve pain control and anesthesia care.
IstanbulAges 18 years+ - NCT07819630Recruiting
Skin stimulation effects on brain activity during abdominal surgery
This study is testing whether a gentle, non-invasive electrical stimulation on specific points on your skin (called acupoints) can affect the brain's electrical activity during abdominal surgery under general anesthesia. It may help researchers understand how this therapy works and potentially improve recovery in the future.
BeijingAges 18–80 - NCT07822048Recruiting
Ready-made beef meals for firefighter recovery after firefighting tasks
This study tests whether eating only ready-made beef meals for a few days helps firefighters recover better after doing firefighting drills.
Fort Worth, TexasAges 18–60 - NCT07819682RecruitingPhase 4
Dexamethasone and spinal anesthesia duration
This trial tests if adding dexamethasone, a common steroid medicine, to the spinal anesthetic can make the numbness last longer. This may help patients having surgery on the lower belly, pelvis, or legs.
Rawalpindi, Punjab ProvinceAges 20–40 - NCT07825506Enrolling by invitation
Nerve glide exercises for fibromyalgia pain and daily function
This study tests whether adding gentle nerve glide exercises to standard care can reduce pain and improve everyday function in women with fibromyalgia. It may offer a non-drug way to feel better.
Santiago, Santiago MetropolitanAges 18 years+ - NCT07824999Recruiting
Sutureless hemorrhoidectomy versus standard ligation for advanced hemorrhoids
This trial compares two surgical approaches for advanced (grade III or IV) hemorrhoids. One is a newer sutureless technique and the other the standard ligation (tying) method. It aims to see which provides better relief from symptoms like bleeding and pain.
SohagAges 18 years+ - NCT07824258RecruitingPhase 1
Pain relief study after vasectomy
This study tests whether a pain-relief method helps reduce discomfort after a vasectomy. It may help you recover more comfortably.
New York, New YorkAges 18–65 - NCT07824050Recruiting
Studying dangerous heart rhythms after a heart attack
This study looks at people who had a heart attack or cardiac arrest to find out which dangerous heart rhythms can happen afterward. The goal is to improve care and prevent future problems.
Eindhoven, North BrabantAges 18 years+ - NCT07820592Enrolling by invitation
Pre-surgery exercises to speed recovery after rotator cuff repair
This study tests whether doing exercises before your shoulder surgery helps you recover faster and better after rotator cuff repair. If you are scheduled for arthroscopic shoulder surgery, this program might help you regain strength and movement more quickly.
TemucoAges 50 years+ - NCT07819565Recruiting
Pork protein for firefighter recovery
This study tests whether eating pork protein helps firefighters recover faster after physically demanding fireground simulations. If you join, you'll eat provided meals and avoid certain pain relievers before testing, so we can see how your body responds.
Fort Worth, TexasAges 18–60 - NCT07822932Recruiting
Ear nerve stimulation for HIV-related nerve pain
This study tests a gentle ear stimulation device that may ease tingling, burning, or numbness from HIV-related nerve damage in the hands and feet. It could offer a drug-free way to manage nerve pain.
Miami, FloridaAges 50 years+ - NCT06481072Recruiting
Digital therapy for kids with chronic stomach pain
This trial tests a digital (online) therapy program to help children with chronic stomach pain. It's designed for kids ages 8 to 14 who have been diagnosed with a functional abdominal pain disorder and can use a computer or tablet at home.
GothenburgAges 8–14 - NCT06488547Recruiting
Stress and muscle health study for Greek workers
This trial looks at how stress affects muscle and bone health in employees. If you join, you'll answer questions and be measured with simple electronic devices. The goal is to find ways to help workers stay healthy.
Larissa, Biopolis- LarissaAges 19 years+ - NCT07811024Recruiting
Strolimus-coated balloon for blocked coronary arteries
This study tests a balloon coated with a drug that may help keep arteries open after they've been cleared, especially for people with a narrowing inside a previously placed stent or in a small heart artery. It's a first-time-in-humans study to check if the treatment is safe and works.
TashkentAges 21 years+ - NCT07810816Recruiting
Genetic testing for personalized pain relief after surgery
This study looks at how your genes affect your body's response to tramadol, a painkiller given through a pump after surgery. The goal is to see if your genetic makeup influences pain relief and side effects, which could help personalize pain treatment in the future.
Medellín, AntioquiaAges 18 years+ - NCT06491121Recruiting
Can high-intensity training with a smartphone help chronic back pain?
This trial tests if a technology-supported high-intensity exercise program can help adults with chronic low back pain. You'll use your own smartphone to help guide the training and attend regular therapy sessions.
Wilrijk, AntwerpenAges 18–65 - NCT07813429Recruiting
Neck posture and pain changes after sleeve gastrectomy
This study looks at how weight-loss surgery (sleeve gastrectomy) may affect the position of your neck, how well your neck moves, and any neck pain you might have. You will be followed for a year to see if losing weight helps improve your neck health.
Istanbul, IstanbulAges 18–65
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,575 recruiting pain medicine studies from the U.S. registry right now, out of 6,452 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.