Clinical trials
Acute Ischemic Stroke clinical trials
Below are recruiting acute ischemic stroke clinical trials, each written for real people, not researchers. We’re tracking 458 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07253181RecruitingPhase 3
Stroke clot-busting drug before transfer for artery clearing
This trial tests whether giving a clot-busting drug (tenecteplase) before transferring you to a hospital that can do a procedure to remove the clot improves outcomes for people who had a stroke up to 24 hours earlier. You may qualify if you have a blockage in a large artery in the front of your brain and can still get the procedure.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04942041Recruiting
Thrombectomy for large stroke blockages at low-volume centers
This study tests whether using a procedure called mechanical thrombectomy at smaller stroke centers can improve outcomes after a large-vessel stroke. It may help people who have a major artery blockage get timely treatment, with measured effects on complications and survival.
Kristiansand, AgderAges 18–100 - NCT06352619Recruiting
Lowering blood pressure after clot removal for stroke
This trial tests whether lowering blood pressure soon after a clot-removal procedure for stroke can improve recovery. It is for people whose blood pressure remains high after the procedure.
Sydney, New South WalesAges 18 years+ - NCT07002476RecruitingPhase 3
Early aggressive cholesterol-lowering after stroke with clot removal
This trial tests whether quickly starting an aggressive cholesterol-lowering treatment after a stroke improves recovery. It is for people who are about to have a procedure to remove a large blood clot from their brain.
ShanghaiAges 18 years+ - NCT05976685Recruiting
Close the left atrial appendage after stroke despite blood thinners
This study tests whether closing a heart pouch called the left atrial appendage can prevent future strokes in people with atrial fibrillation who had an ischemic stroke even while taking blood thinners. It may help reduce stroke risk by blocking a common place where clotting can start.
BrugesAges 18 years+ - NCT07049692Recruiting
Hyperbaric oxygen after stroke clot removal study
This trial tests if hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can help people recover better after having a stroke caused by a large clot in the front part of the brain. It is for people who recently had a clot removal procedure and have some remaining disability but are still awake and aware.
Beijing, Beijing MunicipalityAges 35–75 - NCT07299994Recruiting
Intravenous thrombolysis for specific brain strokes
This trial tests whether a clot-busting drug given through a vein can help people with certain types of deep brain strokes that happen in small arteries. It looks at patients who can be treated within 24 hours of symptoms starting.
Vienna, State of ViennaAges 18 years+ - NCT04839887Recruiting
Quality of life after stroke in adults aged 18–65
This trial looks at what affects quality of life after an ischemic stroke (a type of stroke caused by a blocked blood vessel) in younger adults. You may be able to join if you can complete questionnaires about your recovery and daily life.
OlomoucAges 18–65 - NCT06212674RecruitingPhase 4
Stroke prevention: combined heart procedure for atrial fibrillation
This study tests a combined approach — a catheter ablation to fix the irregular heartbeat (atrial fibrillation) and a device to close the left atrial appendage — in people who recently had a stroke caused by a clot. The goal is to prevent future strokes and reduce the need for long-term blood thinners.
Katowice, Upper SilesiaAges 18–75 - NCT06674356Recruiting
Chin tuck exercise for swallowing after stroke
This trial tests a simple neck exercise (chin tuck against resistance) to help people who have trouble swallowing after a recent stroke. The goal is to see if this exercise improves swallowing safety and strength.
TaipeiAges 18–100 - NCT07203625RecruitingPhase 4
Tenecteplase before transfer for basilar artery stroke
This trial tests if a clot-busting drug called Tenecteplase helps people with a severe type of stroke in the back of the brain (basilar artery occlusion) when given 4.5 to 24 hours after symptoms start. Patients will then be moved to a hospital that can remove the clot. The goal is to see if the drug improves recovery.
BeijingAges 18 years+ - NCT07594314RecruitingPhase 2/Phase 3
Minocycline after stroke clot removal surgery
This trial tests whether minocycline, an antibiotic, can reduce brain damage when given after successful clot removal surgery for acute stroke. The goal is to see if this medication helps patients recover better.
Wuhan, HubeiAges 18 years+ - NCT05832762Recruiting
Clot-buster procedure for blocked neck artery stroke
This trial studies whether an emergency clot-removal procedure through the blood vessels (endovascular treatment) helps people who have a stroke caused by a blocked internal carotid artery in the neck. It compares outcomes in patients treated urgently when imaging shows the blockage is likely the main cause.
Montpellier, FanceAges 18 years+ - NCT05199662RecruitingPhase 3
IV clot-busting medicine for stroke when standard options don’t fit
This trial tests whether giving IV TNK (tenecteplase) plus standard stroke care can improve outcomes in some people who have a new stroke but cannot get alteplase (another clot-busting drug) and do not have a large blocked artery that can be treated with a procedure. It’s meant for strokes with “mismatch” findings on scans that suggest salvageable brain tissue.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07509645RecruitingPhase 3
Testing a new drug with clot removal for severe back-of-the-brain stroke
This trial checks if adding an interleukin-6 receptor inhibitor (a drug that reduces inflammation) to standard emergency clot removal can improve recovery for people with a severe stroke affecting the back part of the brain (posterior circulation). It is for patients who need urgent treatment within 24 hours of symptom onset.
Suzhou, AnhuiAges 18 years+ - NCT06904911RecruitingPhase 2
Study of tenecteplase into the artery after clot removal for stroke
This study tests a clot-dissolving drug called tenecteplase given directly into the artery after a mechanical thrombectomy (clot removal). The goal is to see if it helps improve blood flow to the small vessels in the brain after the main clot is removed.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07727395RecruitingPhase 3
Clot-busting drug after successful clot removal for stroke
This trial tests whether giving a clot-busting drug (alteplase) directly into the brain artery after a successful clot removal improves recovery in people with severe stroke. It is for patients who have had a thrombectomy and still have a large blocked artery in the front of the brain.
An GiangAges 18 years+ - NCT06370182Recruiting
New catheter for clot removal in disabling stroke
This trial tests a new catheter device (ANA Funnel) for removing large blood clots from the brain in people having a disabling stroke. The goal is to see if it safely removes clots better than standard treatment.
Jacksonville, FloridaAges 22–85 - NCT05970406Enrolling by invitation
High-intensity swallow therapy after ischemic stroke
This trial tests a more intensive swallow-therapy program for people with difficulty swallowing soon after an ischemic stroke. It may help improve safety and function when eating and drinking.
Baltimore, MarylandAges 18–99 - NCT07111559RecruitingPhase 4
Comparing clot-busting drug versus two blood thinners for small stroke
This study tests whether a clot-busting drug (rt-PA) or a combination of two blood thinners (DAPT) works better for people having a small stroke caused by a blocked tiny artery in the brain. It aims to find the safest and most effective treatment within the first few hours after symptoms start.
ChūōAges 18 years+ - NCT07740018Recruiting
Stroke treatment study for blocked brain arteries
This study looks at how well a procedure to remove blood clots from blocked brain arteries works for people who have had a stroke. It aims to see what factors help people recover better, which could help guide treatment decisions.
SohagAges 18–80 - NCT07084012RecruitingPhase 2
Stem cell treatment for recent stroke
This trial tests whether a single infusion of umbilical cord stem cells can help people recover from a recent ischemic stroke (stroke caused by a clot). It is for patients who have had their stroke within the last 72 hours and have moderate to severe symptoms.
Beijing, Beijing MunicipalityAges 18–75 - NCT03153683Recruiting
Brain and blood clot registry for adults having brain blood tests
This study is a registry, meaning it collects information from people having surgery or procedures for problems involving blood vessels in the brain. It may help researchers better understand brain blood conditions and clots by tracking patterns over time.
Lexington, KentuckyAges 18 years+ - NCT04078373Recruiting
Rehab study of bladder problems after recent stroke
This trial looks at urinary (bladder) problems in people who are in the early recovery phase after a stroke, while they receive inpatient rehabilitation. It may help improve how bladder issues are managed during rehab after stroke.
LjubljanaAges Any age
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Common questions
- Are there clinical trials for acute ischemic stroke?
- Yes. Clin2 currently lists 458 recruiting acute ischemic stroke studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute ischemic stroke trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute ischemic stroke trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.