Clinical trials
Occlusion clinical trials
Below are recruiting occlusion clinical trials, each written for real people, not researchers. We’re tracking 319 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06635902RecruitingPhase 2
Citrulline for sickle cell pain crisis
This trial tests if an intravenous medication called L-citrulline can help treat pain crises in children and young adults with sickle cell disease. Participants receive either the study drug or a placebo while in the hospital for a severe pain episode.
Washington D.C., District of ColumbiaAges 4–21 - NCT05972018RecruitingPhase 4
Liposomal numbing medicine for belly incisions in vascular surgery
This study compares two numbing options for pain control after open belly (mid-abdominal) vascular surgery: a longer-lasting numbing drug in the belly muscle layer versus a different numbing drug and catheter. It aims to see which approach better reduces postoperative pain and opioid use, and may help improve recovery.
Hartford, ConnecticutAges 18–80 - NCT06193954Recruiting
Vibrating guidewire for chronic heart artery blockages
This trial tests a special vibrating guidewire to help open heart arteries that have been completely blocked for a long time, when standard wires have failed. It may help you if you have a stubborn blockage requiring a gentle approach.
Atlanta, GeorgiaAges 18 years+ - NCT06275386Recruiting
Drug-coated balloon for chronic heart artery blockages
This trial tests whether a special balloon coated with medicine (drug-coated balloon) can safely open a completely blocked heart artery, instead of using a permanent stent. It may be an option for people who have chronic chest pain or shortness of breath due to a long-standing blockage.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT06184126Recruiting
Virtual reality for sickle cell pain in the emergency room
This trial tests whether using a virtual reality (VR) headset, along with your usual pain treatment, can help reduce pain during a sickle cell crisis. It is for adults with sickle cell disease who are in the emergency department and receiving IV opioids for a vaso-occlusive crisis.
Baltimore, MarylandAges 18 years+ - NCT06137521Recruiting
Heart artery blockage study
This study looks at people with a long-standing complete blockage in a heart artery. The goal is to understand risk factors and outcomes, which may help guide future treatments.
ShanghaiAges 18 years+ - NCT06155032Recruiting
Clot Removal for Worsening Mild Stroke
This trial tests whether emergency clot removal (endovascular therapy) can help people whose mild stroke gets worse within a week. It's for those who have a blockage in a large brain artery and enough healthy brain tissue to save.
Fuyang, AnhuiAges 18 years+ - NCT06096142Recruiting
A drug-coated stent for dialysis access narrowing
This trial tests a new covered stent that slowly releases a drug to keep the dialysis access (a surgically created blood vessel) open. It is designed for people whose access is narrowed or blocked and needs a procedure to restore blood flow and allow dialysis to continue.
Salvador, Estado de BahiaAges 18 years+ - NCT05983757Recruiting
Clot retrieval for smaller brain artery strokes
This trial tests if removing clots from smaller arteries in the brain (not the main ones) helps people who had a stroke and can't get standard clot-busting medicine. It compares clot removal to usual care for strokes caused by these medium-sized vessel blockages.
Atlanta, GeorgiaAges 18 years+ - NCT05811364Recruiting
Stent versus bare-metal treatment for blocked leg arteries
This study compares a new balloon-expandable stent to standard bare-metal stenting to treat complex blockages in the iliac arteries (main blood vessels to the legs). It may help people with symptoms like leg pain with walking, pain at rest, or minor tissue injury by improving blood flow and reducing repeat procedures.
Little Rock, ArkansasAges 18 years+ - NCT05440448Recruiting
Patch-free therapy for lazy eye in children
This study tests a patch-free treatment approach for “lazy eye” (amblyopia) in children. It may help some kids improve vision without using traditional eye patches, but it requires a willingness to skip standard patching during the study.
Dallas, TexasAges 3–12 - NCT05105633RecruitingPhase 2/Phase 3
Tenecteplase for basilar stroke within an extended time window
This trial tests whether giving a clot-busting medicine (tenecteplase) can help people with a specific type of stroke caused by a basilar artery blockage, even if treatment starts later than usual. It aims to improve brain recovery and function by reopening the blocked artery.
Bankstown, New South WalesAges 18 years+ - NCT04583644Recruiting
Fetal airway balloon procedure for severe left lung underdevelopment
This pilot study tests a fetal procedure (placing a tiny balloon in the fetus’s airway) to improve lung growth in pregnancies affected by severe left congenital diaphragmatic hernia (CDH). You may be eligible if your baby’s condition is isolated to the left side and the testing shows very high lung underdevelopment, and if you can meet study and payment requirements.
San Francisco, CaliforniaAges 18 years+ - NCT03756870Recruiting
Stent procedure vs best medical care for blocked heart arteries
This trial studies whether opening a completely blocked heart artery (a CTO) with a procedure and stent helps reduce areas of low blood flow in the heart, compared with the best medicines alone. It uses heart scans to find people likely to benefit and then checks results again at 6 months.
AmsterdamAges 18 years+ - NCT03667196Recruiting
Test opening blocked heart arteries using two different procedures
This trial studies whether two ways of threading a device to open a long-term blocked coronary artery are both safe and effective. You may qualify if you have a chronic total blockage and heart-related symptoms, and you can follow the study follow-up plan.
AnyangAges 19 years+ - NCT03353584Recruiting
Virtual reality for pain relief during sickle cell pain crises
This trial tests whether a virtual reality (VR) experience can help reduce pain during a sickle cell “vaso-occlusive crisis,” which is an episode of sudden, severe pain. It’s offered alongside the care team’s usual pain management to see if VR makes pain feel better.
Memphis, TennesseeAges 6–25 - NCT03496792Recruiting
Study of blood pressure changes when standing up
This study checks how your blood pressure changes when you go from lying down to standing. It may help researchers understand why some people get “orthostatic hypertension” (higher blood pressure when standing) and how that reflex works.
Hershey, PennsylvaniaAges 18 years+ - NCT02699957Recruiting
Left Atrial Appendage Closure Registry Study
This study tracks patients who have a minimally invasive procedure to close off a small pouch in the heart called the left atrial appendage. The procedure aims to reduce stroke risk, and this registry collects information about how patients do after the procedure.
Washington D.C., District of ColumbiaAges 18 years+ - NCT02530073Recruiting
FETO procedure for babies with isolated left diaphragmatic hernia
This trial studies a fetal procedure (FETO) that temporarily blocks the baby’s windpipe to help lung growth before birth. It may help babies with severe lung underdevelopment from an isolated left diaphragmatic hernia (CDH) who meet specific pregnancy and fetal criteria.
Hartford, ConnecticutAges 18 years+ - NCT07878247Recruiting
Splint therapy for jaw pain and muscle spasms
This trial tests a dental splint (a custom mouthpiece) to see if it helps with jaw pain, muscle spasms, and chewing difficulties caused by temporomandibular disorders (TMD) or bruxism (teeth grinding).
CairoAges 18–60 - NCT05490238Recruiting
Wrist vs arm access for complex heart procedures
This study compares using the wrist (radial artery) versus a different access site (conventional radial access approach) during complex, larger “bore” heart procedures to open blocked coronary arteries. It aims to see which approach is safer and works better for challenging cases like chronic blockages or heavily calcified arteries.
ArlonAges 18 years+ - NCT01889459Recruiting
Registry after stent procedure for blocked heart arteries
This study follows people who had a stent placed for a long-standing blockage in a heart artery (called a CTO). It’s mainly a “registry” to understand outcomes after these procedures and help improve care in the future.
KurashikiAges 20 years+ - NCT03428048Recruiting
NEXUS Registry for coronary artery disease or Afib patients
This is a research registry that collects health information about people with coronary artery disease or Afib. It may help doctors and researchers better understand these heart conditions and improve future care.
Glenwood Springs, ColoradoAges 18 years+ - NCT03643718Recruiting
Emergency surgery and trauma patient registry online
This trial is a web-based registry that collects information about people who need emergency surgical or non-surgical treatment for sudden (acute) problems. Your information can help doctors better understand and improve emergency care and decision-making.
PisaAges Any age
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Common questions
- Are there clinical trials for occlusion?
- Yes. Clin2 currently lists 319 recruiting occlusion studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a occlusion trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a occlusion trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.