Clinical trials
Respiratory Failure clinical trials
Below are recruiting respiratory failure clinical trials, each written for real people, not researchers. We’re tracking 209 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06319274RecruitingPhase 2
Prostacyclin for lung infection patients on a ventilator
This study tests a medicine called prostacyclin (given through a vein) to see if it helps people on a breathing machine with a lung infection. The goal is to reduce inflammation and improve recovery.
CopenhagenAges 18 years+ - NCT05540834RecruitingPhase 2
Testing blood-clot guidance for ICU patients with severe lung failure
This Phase 2 trial tests whether using a blood test that shows clotting strength and “clot breakdown time” can help guide treatment for people in the ICU with acute respiratory failure from infection. If you qualify, the team will use these blood results to decide on clot-related therapy and compare outcomes to standard care.
Liverpool, New South WalesAges 18–75 - NCT04236726Recruiting
Quality of life study for people with chronic breathing failure
This study looks at how chronic respiratory failure affects day-to-day quality of life. It enrolls people who use breathing support at home or in care, and may help clinicians understand what support works best for patients’ daily living.
LondonAges 18 years+ - NCT07189078Recruiting
Comparing intubation methods for patients with low blood oxygen
This study tests two different ways to place a breathing tube in patients who are in intensive care with very low oxygen levels and need help breathing. The goal is to find which method is safer and works better for patients like you.
AngersAges 18 years+ - NCT05675345Recruiting
Negative pressure breathing device for sudden low-oxygen breathing failure
This trial studies a continuous negative external pressure device (a “cuirass” that helps breathing) for people with sudden, severe low oxygen levels. It aims to see whether the device improves breathing and oxygen levels without needing immediate intubation.
New York, New YorkAges 18 years+ - NCT06007495Recruiting
Testing a new mask for carbon dioxide removal in breathing failure
This study tests a new mask designed to help remove carbon dioxide more effectively. It is for hospitalized adults with breathing failure who need non-invasive breathing support or high oxygen.
Montreal, QuebecAges 18 years+ - NCT07175194Recruiting
Matching lung scans to ventilator settings in acute breathing failure
This study uses two lung imaging tests—CT scan and EIT (a non-invasive electrical test)—to find the best ventilator pressure for people with sudden breathing failure. The goal is to tailor settings to your lungs and potentially improve breathing support.
Milan, MilanAges 18 years+ - NCT07607080Recruiting
Predicting Treatment Success for High-Flow Oxygen Support
This study helps doctors predict which patients receiving high-flow oxygen through a nasal tube will need additional breathing support. Researchers use blood tests and clinical information to identify who might need a ventilator, allowing earlier interventions if needed.
Barcelona, CataloniaAges 18 years+ - NCT06744790Recruiting
Predicting breathing trouble after surgery with a new sensor
This trial tests a new sensor that monitors your breathing to predict if you might have trouble after surgery. It is for people who are staying overnight in the hospital and getting extra oxygen through a face mask.
Baltimore, MarylandAges 18 years+ - NCT05990101Recruiting
Awake prone positioning for low oxygen in the ICU
This trial tests whether lying on your stomach (prone positioning) while awake can help you breathe better when you are in the ICU with low oxygen levels. It may reduce the need for a breathing tube.
KaunasAges 18 years+ - NCT06912360Recruiting
CPAP support for severe breathing failure in Burkina Faso
This trial tests if CPAP, a breathing machine that keeps airways open, helps adults with severe breathing problems and low oxygen levels. It is for people in Burkina Faso who need extra oxygen to breathe well.
Bobo-Dioulasso, HouetAges 18 years+ - NCT07451977Recruiting
Oxygen during a 6-minute walk test for lung disease
This trial tests whether adding extra oxygen during a 6-minute walk test helps people with chronic lung disease breathe better. It is for people with COPD or interstitial lung disease who have low oxygen levels, either during exercise or all the time.
Lumezzane, BresciaAges 18 years+ - NCT06624254Enrolling by invitation
Breathing machine settings for lung recovery in ICU
This study looks at how a specific type of breathing machine setting (adaptive pressure control) affects your lungs and recovery. It aims to find the best way to support breathing for people in the ICU with respiratory failure.
La Jolla, CaliforniaAges 18 years+ - NCT04158479Recruiting
Registry for people on ECMO life support
This registry collects information about people who are placed on ECMO, a heart-lung machine used to support breathing and/or circulation. It may help doctors better understand who benefits and how to manage ECMO in the future.
Beijing, Beijing MunicipalityAges Any age - NCT06881927RecruitingPhase 4
Reducing anti-rejection meds in ICU for kidney transplant patients
This study tests whether quickly reducing your anti-rejection medicines during a life-threatening ICU stay can help your kidneys recover and improve your overall outcome. It is for kidney transplant recipients with septic shock or severe breathing failure.
StrasbourgAges 18 years+ - NCT07379242Recruiting
Lung recruitment test for breathing failure patients on a ventilator
This trial uses a special imaging technique (electrical impedance tomography) to find the best ventilator settings for patients with acute breathing failure. It may help doctors tailor treatment to improve lung function.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07265882Recruiting
Bedside test for breathing tube patients
This trial uses a simple bedside test to evaluate patients who are on a breathing machine and not breathing on their own. It may help doctors better understand and manage acute respiratory failure.
Pavia, PaviaAges 18–90 - NCT04545242RecruitingPhase 4
Dexamethasone for severe lung failure from infections on ventilators
This trial studies whether dexamethasone (a steroid medicine) improves outcomes in adults who have sudden, severe breathing failure caused by an infection while they are on a breathing machine. It may help reduce inflammation in the lungs during critical illness.
Terrassa, BarcelonaAges 18 years+ - NCT06047405Recruiting
Comparing two breathing machine settings for high carbon dioxide failure
This trial tests two different ways of setting a noninvasive breathing machine (BiPAP) to help patients with high carbon dioxide levels in the blood due to respiratory failure. It aims to find which setting works better for patients at Lenox Hill Hospital.
New York, New YorkAges 18 years+ - NCT06931938Recruiting
Awake Prone Position for Pneumonia and Low Oxygen
This trial tests whether lying on your stomach while awake (called awake prone positioning) can help people with pneumonia who have low oxygen levels in the ICU. It aims to see if this simple position change can improve breathing and avoid the need for a breathing machine.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT07099144Recruiting
Inhaled nitric oxide for newborns with breathing failure and high blood pressure in the lungs
This trial tests whether inhaled nitric oxide gas can help full-term newborns who have severe breathing problems and high blood pressure in their lungs. It aims to improve oxygen levels and reduce the need for more intensive support.
Guangzhou, GuangdongAges Up to 1 week - NCT07168213Recruiting
Comparing oxygen monitors during high-flow nasal oxygen
This study tests whether two different oxygen monitors change how much extra oxygen doctors give you during high-flow nasal oxygen therapy. If you are in the ICU and already on this type of oxygen, the researchers want to see if using a different monitor helps keep your oxygen levels stable.
Québec, QuebecAges 18 years+ - NCT07051967Recruiting
Comparing recovery after ICU for pregnant and non-pregnant COVID-19 patients
This study looks at how COVID-19 and respiratory failure affect recovery after intensive care. It compares pregnant patients to non-pregnant patients to learn more about the long-term effects.
BerlinAges 18 years+ - NCT06341972Recruiting
Recovering after breathing support: a self-help program
This study tests a self-management program to help people who felt anxious after being on a breathing machine in the ICU. It aims to improve emotional recovery and quality of life.
Baltimore, MarylandAges 18 years+
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Common questions
- Are there clinical trials for respiratory failure?
- Yes. Clin2 currently lists 209 recruiting respiratory failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.