Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,773
- Phase 2214
- Phase 4199
- Phase 1182
- Phase 3138
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis173
- Rheumatoid Arthritis131
- Fibromyalgia104
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Degenerative Disc Disease39
- Psoriatic Arthritis39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital24
- Hacettepe University23
- Tanta University22
Where studies are running
- California206
- New York86
- Florida83
- Maryland76
- Arizona71
- Massachusetts71
- Texas66
- Alabama60
- Illinois50
- Pennsylvania47
Recruiting studies4,610 total
- NCT07036445Recruiting
PRP vs steroids for leg pain from a slipped disc
This study compares two treatments—platelet-rich plasma (PRP) and steroids—given as an injection into the spine for leg pain caused by a herniated disc. It's for people who haven't improved after 6 weeks of standard care.
MérignacAges 18 years+ - NCT07034196Recruiting
Comparing RA care: primary care vs. rheumatologist
This study compares RA care from your primary care doctor (with extra training) to care from a rheumatologist. It's for people with stable RA living in northern New York who want to see if primary care can work as well as a specialist.
Potsdam, New YorkAges 18 years+ - NCT07044206Recruiting
Comparing two bone graft materials for lumbar fusion surgery
This trial compares two types of bone graft materials (Magnetos Putty and GlassBone Putty) used in lower back fusion surgery for adults with degenerative disc disease. The goal is to see which material works better for helping the bones fuse together, which may reduce pain and improve function.
Montpellier, FranceAges 18–80 - NCT07043127Recruiting
Strength training after hip replacement with blood flow restriction
This trial tests a new kind of physical therapy after hip replacement. It combines strength exercises with a special technique called blood flow restriction to see if it helps you recover muscle strength faster.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT07039799Recruiting
Virtual reality for arm function in Duchenne
This trial tests whether using virtual reality (VR) games can help improve arm and hand function in people with Duchenne muscular dystrophy. It may be a fun and engaging way to do exercises that strengthen your upper body.
Istanbul, FatihAges 7–18 - NCT07037472Recruiting
Imaging calcium deposits in dermatomyositis patients
This study uses a special imaging technique (photoacoustic/ultrasound) to look at calcium deposits under the skin in people with dermatomyositis. It aims to find patterns that help doctors understand the condition and track how well treatments work.
BeijingAges 18–80 - NCT07039968RecruitingPhase 2
Standard vs. high dose radiation for spine cancer spread
This trial compares standard and higher doses of focused radiation (stereotactic radiosurgery) to treat cancer that has spread to the spine. It aims to find if a higher dose works better while keeping side effects manageable.
TaipeiAges 18 years+ - NCT07043166Recruiting
Heart, kidney, and metabolic health study in Shanghai
This study looks at the link between heart, kidney, and metabolic health in adults living in Shanghai. It follows people who were part of an earlier health study to see how their health changes over time.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07037251Recruiting
Screening for fibromyalgia in suspected endometriosis
This study screens women with suspected endometriosis for fibromyalgia during their first visit to the clinic. It aims to find out if the two conditions often occur together so they can be treated together.
AshdodAges Any age - NCT07043101Recruiting
Virtual reality for leg rehab with Vector system
This study tests if using a virtual reality headset can help people who are already using a Vector walking system in the hospital. The virtual reality shows goals to aim for while walking, which may make rehab more engaging and effective.
Schenectady, New YorkAges 18 years+ - NCT07034105Recruiting
Walking patterns in healthy people and stroke survivors
This study compares how people walk on different surfaces and with body weight support. It aims to understand walking differences between healthy individuals and stroke survivors, which could help design better rehab programs.
DhakaAges 18–75 - NCT07037888RecruitingPhase 4
Ketorolac for pain after hip arthroscopy
This study tests whether ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), helps manage pain after hip surgery. It may offer an opioid-sparing option for patients with femoroacetabular impingement (FAI).
Detroit, MichiganAges 18–89 - NCT07043335Recruiting
Mesotherapy vs. shock wave for tennis elbow pain
This trial compares two treatments for tennis elbow: mesotherapy (injections into the skin) and shock wave therapy (sound waves). It aims to find which works better for pain that has lasted at least 6 weeks.
IstanbulAges 18–65 - NCT07040878Recruiting
Antigravity treadmill after hip or knee replacement
This study tests whether walking on a special antigravity treadmill (which reduces weight on your joints) helps people recover faster after hip or knee replacement surgery. It's designed for people who are 60 or older and can walk on their own.
Trzebnica, Lower Silesian VoivodeshipAges 60–75 - NCT01793168Recruiting
Rare disease registry and history study
This study keeps a registry (a structured list) of people with rare diseases and may also track how the condition changes over time. It can help researchers better understand rare illnesses and find gaps in care, which may improve future treatments.
Sioux Falls, South DakotaAges Any age - NCT03773003Recruiting
Study of fatigue caused by cancer or chronic fatigue
This study looks at why fatigue happens in people with cancer and, in some cases, in people with chronic fatigue conditions. It may help researchers better understand the causes of fatigue so future treatments can be improved.
Homburg, SaarlandAges 18–80 - NCT07025252Enrolling by invitation
VersaWrap patch for Achilles tendon repair
This trial tests a special wrap (VersaWrap) used during surgery to repair a torn or damaged Achilles tendon. It may help the tendon heal better and could be an option for people who need this type of surgery.
Sacramento, CaliforniaAges 18–90 - NCT07028476Recruiting
New care for possible ACL tear using automated laxity test
This trial is testing a new approach to care for people with a possible torn ACL (the ligament in your knee). It uses a special exam to measure knee looseness automatically, and the goal is to give you a faster path to the right treatment.
AngersAges 18 years+ - NCT07031791Recruiting
Questionnaire on hand and arm use after injury
This study tests a new questionnaire that helps doctors understand how people use their arms and hands after an injury or condition. It may help improve future care and treatment planning.
AngersAges 18 years+ - NCT07024407RecruitingPhase 1/Phase 2
Study of andecaliximab for preventing bone growth after spinal cord injury
This trial tests a drug called andecaliximab to see if it can stop abnormal bone growth (heterotopic ossification) that sometimes happens after a spinal cord injury. It is for people who are at high risk for this bone growth and aims to prevent it from forming.
Denver, ColoradoAges 18–89 - NCT07028268RecruitingPhase 2
Testing a new drug for bone metastases from solid tumors
This trial tests a new drug called SHR-2017 for people with solid tumors that have spread to the bones. The study aims to see if the drug can help manage pain and other effects of bone metastases.
Guangzhou, GuangdongAges 18 years+ - NCT06985459Recruiting
Splint for stiff finger joints after injury
This study tests whether a special splint called a 'relative motion orthosis' can help people regain movement in a stiff finger joint after an injury or surgery. If you have a recent finger joint problem and are willing to do hand therapy, this trial may help you recover better.
Bern, Canton of BernAges 18 years+ - NCT07030205Recruiting
Brain imaging study for women with osteoporosis
This study uses brain scans (MRI) to look at how the brain might be linked to bone health in women with osteoporosis. It compares women with osteoporosis to healthy women of the same age.
Clermont-FerrandAges 50 years+ - NCT07026305Recruiting
Comparing surgical approaches for lumbar spinal stenosis
This study is comparing two surgical approaches for patients with lumbar spinal stenosis (narrowing of the lower spine). It aims to see if a less invasive surgery works as well as a more extensive procedure, which may help patients recover faster.
MadridAges 50 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,529 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.