Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,773
- Phase 2214
- Phase 4199
- Phase 1182
- Phase 3138
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis173
- Rheumatoid Arthritis131
- Fibromyalgia104
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Degenerative Disc Disease39
- Psoriatic Arthritis39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital24
- Hacettepe University23
- Tanta University22
Where studies are running
- California206
- New York86
- Florida83
- Maryland76
- Arizona71
- Massachusetts71
- Texas66
- Alabama60
- Illinois50
- Pennsylvania47
Recruiting studies4,610 total
- NCT07053943Enrolling by invitation
Comparing single vs. multiple antibiotic doses for hip and knee replacement
This study compares two ways of giving antibiotics before hip or knee replacement surgery to see which one leads to fewer infections needing another surgery. It may help doctors choose the best antibiotic approach for patients having their first joint replacement.
Amsterdam, North HollandAges Any age - NCT07051577Recruiting
Brain-Based Training for Young Archers
This study tests a special brain-based training program for young archers aged 15–18. The goal is to see if these exercises can improve your shooting accuracy and how your muscles work.
Istanbul, IstanbulAges 15–18 - NCT07047846Recruiting
Bowen technique vs. soft tissue therapy for frozen shoulder pain
This study compares two massage-like treatments (Bowen technique and dynamic soft tissue mobilization) to see which better reduces pain, improves movement, and helps daily function in people with frozen shoulder. It only includes diabetic patients with specific stages of frozen shoulder.
Lahore, Punjab ProvinceAges 50–80 - NCT07054437Recruiting
Assessing gross motor skills in preschoolers via video
This trial uses videos to evaluate how healthy preschool children develop gross motor skills like walking. It may help understand typical movement in kids ages 1 to 6.
TaoyuanAges 1–6 - NCT07045519Recruiting
Vibration therapy for walking and balance in cerebral palsy
This study tests whether a gentle vibrating device applied to the legs can improve walking and balance in children with cerebral palsy. It may help reduce muscle tightness and make moving easier.
AnkaraAges 4–18 - NCT07045714Recruiting
Endoscopic back surgery for spinal stenosis
This study looks at a newer, less invasive type of back surgery called endoscopic laminotomy. It may help people with lumbar spinal stenosis (narrowing of the spinal canal) who still have leg or back pain after trying physical therapy and pain medicines for at least 3 months.
San Pedro Garza García, Nuevo LeónAges 18–74 - NCT07053176Enrolling by invitationPhase 4
Neck injection for dizziness linked to neck pain
This trial tests whether a local anesthetic injection in the neck (paravertebral lidocaine) can reduce dizziness that is related to neck pain or stiffness. It may help if your dizziness started along with neck pain, trauma, or limited movement.
Fara in Sabina, RietiAges 18–80 - NCT07053566Enrolling by invitation
Back muscle strengthening for rotator cuff tendinopathy
This study tests whether strengthening a back muscle (latissimus dorsi) helps people with rotator cuff tendinopathy. You may be able to join if you have had shoulder pain for at least 3 months and meet certain medical criteria.
AnkaraAges 18–50 - NCT07054450Enrolling by invitation
Assessment and rehabilitation for chronic pinched nerve in the neck
This trial tests a program of assessment and rehabilitation (including physical exercise and possibly a nutraceutical supplement) for people with chronic cervical radiculopathy — a pinched nerve in the neck causing pain, numbness, or weakness in the arm. It may help reduce pain and improve function without surgery.
CraiovaAges 50–79 - NCT07045896Recruiting
Fucoidan for active rheumatoid arthritis
This trial tests a seaweed extract called fucoidan to see if it can help people with active rheumatoid arthritis that is not well controlled by their current treatments. If you have moderate-to-high disease activity despite therapy, you may be able to join.
BeijingAges 18–65 - NCT07047703RecruitingPhase 1/Phase 2
Study of an investigational drug for axial spondyloarthritis
This trial tests a new oral medication that may reduce inflammation and improve symptoms in people with axial spondyloarthritis. It is in early phases, meaning the drug is still being studied for safety and effectiveness.
BirtinyaAges 18–65 - NCT07050277RecruitingPhase 3
Morphine for bladder issues after knee replacement
This study tests whether adding morphine to spinal anesthesia can reduce trouble urinating after a second knee replacement surgery. It may help you avoid needing a catheter after surgery.
Toronto, OntarioAges 21 years+ - NCT06629376RecruitingPhase 1
Testing a new gout drug for safety and effect on uric acid
This trial tests an experimental drug, SSS11, to see if it is safe and how it affects uric acid levels in people with gout and high uric acid. You may not take other gout medicines during the study.
ShanghaiAges 18–65 - NCT07040930RecruitingPhase 1
Testing the safety of GenSci120 in healthy adults
This study tests a new drug called GenSci120, given as multiple injections under the skin, to see if it is safe in healthy adults. It will also measure how the drug moves through the body and how it affects certain immune markers.
Shanghai, Shanghai MunicipalityAges 18–55 - NCT07038447Enrolling by invitationPhase 1
A study of KITE-363 for people with severe autoimmune diseases
This trial tests a new treatment called KITE-363 for people with certain autoimmune diseases (like lupus, scleroderma, or inflammatory myositis) that haven't improved with standard treatments. The goal is to see if KITE-363 can reduce disease activity and improve symptoms.
Duarte, CaliforniaAges 18 years+ - NCT07037862RecruitingPhase 1/Phase 2
Study of ENTR-601-44 for Duchenne muscular dystrophy (exon 44 skipping)
This trial tests a new medicine called ENTR-601-44 for people with Duchenne muscular dystrophy whose genetic mutation can be treated by skipping a part of the gene called exon 44. The goal is to see if it is safe and helps with muscle function.
GhentAges 4–20 - NCT07038200RecruitingPhase 3
Study of Del-brax (AOC 1020) for People with FSHD
This study tests an experimental medicine called Del-brax (AOC 1020) for people with facioscapulohumeral muscular dystrophy (FSHD). The goal is to see if it can help improve muscle strength and slow the disease. You may be able to join if you have a confirmed FSHD diagnosis and can walk at least 10 meters on your own.
Orange, CaliforniaAges 16–70 - NCT07041099RecruitingPhase 1
Study of CLN-978 for Sjögren's disease
This trial tests an experimental drug called CLN-978, given as a shot under the skin, that helps your immune system target and destroy disease-causing B cells. It's for people with moderate to severe Sjögren's disease who haven't had success with other treatments.
Orlando, FloridaAges 18 years+ - NCT07038824RecruitingPhase 1/Phase 2
A study of ENTR-601-45 for Duchenne MD (exon 45 skipping)
This trial tests an experimental drug called ENTR-601-45 for people with Duchenne muscular dystrophy that can be treated with 'exon 45 skipping.' The goal is to see if it's safe and helps improve muscle function. It's for males between 4 and 20 who can still walk and have enough arm strength.
GhentAges 4–20 - NCT06992375Recruiting
Shoulder manipulation study for volleyball players
This trial tests a shoulder manipulation technique in healthy volleyball players to see if it improves shoulder function and performance. It may help if you play regularly and haven't had recent injuries or surgeries.
GdanskAges 18–30 - NCT06992271Recruiting
Comparing two exercise styles on muscle recovery
This study tests two different types of arm exercises to see how they affect muscle soreness and damage. If you've lifted weights before but aren't currently doing chest presses every week, this may help you understand how your body recovers after different workouts.
Old Westbury, New YorkAges 18–35 - NCT07040878Recruiting
Antigravity treadmill after hip or knee replacement
This study tests whether walking on a special antigravity treadmill (which reduces weight on your joints) helps people recover faster after hip or knee replacement surgery. It's designed for people who are 60 or older and can walk on their own.
Trzebnica, Lower Silesian VoivodeshipAges 60–75 - NCT07044206Recruiting
Comparing two bone graft materials for lumbar fusion surgery
This trial compares two types of bone graft materials (Magnetos Putty and GlassBone Putty) used in lower back fusion surgery for adults with degenerative disc disease. The goal is to see which material works better for helping the bones fuse together, which may reduce pain and improve function.
Montpellier, FranceAges 18–80 - NCT07034105Recruiting
Walking patterns in healthy people and stroke survivors
This study compares how people walk on different surfaces and with body weight support. It aims to understand walking differences between healthy individuals and stroke survivors, which could help design better rehab programs.
DhakaAges 18–75
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,529 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.