Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,838 recruiting studies in this area right now.
By phase
- Not applicable3,969
- Phase 2224
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 276
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis141
- Fibromyalgia102
- Osteoporosis87
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,838 total
- NCT06224634Recruiting
Testing a new drug for airway problems
This trial tests how a drug called anti-IL-17 affects your airways. If you are already planning to take this drug, researchers want to see if it helps with breathing and airway resistance.
Hvidovre, Capital RegionAges 18 years+ - NCT06226272Recruiting
Study of Stryker spine device results
This trial is checking how well a Stryker spine device works in people who need spine surgery. Eligibility depends on the specific device and is decided by the study doctors.
Jacksonville, FloridaAges 18 years+ - NCT06227182Recruiting
Comparing MRI and ultrasound for muscle health
This study compares two imaging methods, MRI and ultrasound, to see how well they measure muscle health. It may help find better ways to monitor muscle conditions without invasive tests.
Nijmegen, GelderlandAges 18–70 - NCT06229964Recruiting
Frozen shoulder treatment: injection and nerve block
This trial compares two treatments for frozen shoulder: a corticosteroid injection into the shoulder joint and a nerve block (injection near the shoulder nerve) to reduce pain and improve movement. It aims to find which approach works better for people with frozen shoulder.
BrusselsAges 18–99 - NCT06232304Recruiting
Program for young people with childhood lupus
This study tests a program to help teenagers and young adults with childhood-onset lupus manage symptoms like fatigue, sadness, or pain. It aims to improve daily life and well-being.
Birmingham, AlabamaAges 12–22 - NCT06234631RecruitingPhase 2
CBD to reduce opioids after knee replacement
This study tests if a daily CBD capsule can help reduce the need for opioid pain pills after a first-time total knee replacement. It is for people with osteoarthritis who are having surgery and are willing to avoid cannabis for a short time before and after.
Ann Arbor, MichiganAges 18–80 - NCT06235645Recruiting
Detecting lung disease in rheumatoid arthritis with ultrasound
This study tests if a lung ultrasound can detect early signs of lung disease in people with rheumatoid arthritis. It may help you if you have certain risk factors, like being male, older, or a smoker.
ToursAges 18 years+ - NCT06237153RecruitingPhase 2
Steroid injection for thumb arthritis pain
This study tests a long-acting steroid injection for thumb arthritis at the base of the thumb. It aims to reduce pain and improve function in people with mild to moderate joint damage.
Stony Brook, New YorkAges 18 years+ - NCT06239649Recruiting
Nerve block before knee replacement for faster recovery
This trial tests whether a numbing injection (nerve block) around the knee before surgery can help you recover faster and feel less pain after a total knee replacement. It is for people with knee osteoarthritis who are ready for their first knee replacement surgery.
Denizli, PamukkaleAges 40–85 - NCT06240299Recruiting
Neurofeedback for chronic pain in rheumatoid arthritis
This trial tests a brain-training technique called neurofeedback to see if it can help people with rheumatoid arthritis who also have chronic widespread pain. It uses a computer to show you your brain activity and teach you to control it, which may reduce pain.
Glasgow, ScotlandAges 18–75 - NCT06242821Recruiting
Yoga for back pain in teen scoliosis
This study tests whether yoga can help reduce back pain in teens with scoliosis (curved spine). You would practice yoga at home through online sessions, as an alternative to or alongside physical therapy.
Baltimore, MarylandAges 10–20 - NCT06243848Recruiting
Injection vs. surgery for carpal tunnel syndrome
This trial compares two treatments for carpal tunnel syndrome: an ultrasound-guided injection and a surgery to take pressure off the median nerve. It aims to see which one provides better relief for symptoms like numbness and tingling.
AfyonkarahisarAges 18–75 - NCT06245109RecruitingPhase 4
Pain medicine study for knee osteoarthritis
This study tests how well different pain medicines work for knee osteoarthritis and looks at brain patterns to understand why some people get more relief. It may help you find a treatment that works best for you.
Chicago, IllinoisAges 41 years+ - NCT06249906Recruiting
Bioceramic material for bone defect repair
This trial tests a new bioceramic material to repair bone defects. It is for adults aged 18 to 65 who are generally healthy and can follow the study plan.
Nanjing, JiangsuAges 18–65 - NCT06249958Recruiting
Personalized rehabilitation after hip or knee replacement
This study looks at how personalized rehabilitation after hip or knee replacement surgery can improve your quality of life. It is for people who had their surgery at IRCCS Galeazzi Orthopedic Institute in 2019.
Milan, ItaliaAges 18 years+ - NCT06250023Recruiting
Oral antibiotics for spinal infection treatment
This trial tests whether oral antibiotics, taken as pills, work as well as IV antibiotics for treating spinal infections. It may be an option if your infection is already improving with a short course of IV antibiotics.
CopenhagenAges 18 years+ - NCT06250491Recruiting
Deep rTMS for Nerve Pain or Fibromyalgia
This study is testing a special type of brain stimulation (deep rTMS) for people with long-term nerve pain or fibromyalgia. The goal is to see if it can help reduce pain that hasn't gotten better with usual treatments.
Boulogne-BillancourtAges 18–80 - NCT06251167Recruiting
Shoe insoles for knee osteoarthritis
This study tests whether shoe insoles can help people with knee osteoarthritis. You might be eligible if you have had knee pain for at least 6 months, your pain is at least moderate, and you also have pain in the same foot.
Vancouver, British ColumbiaAges 50 years+ - NCT06251752Recruiting
Long-term study of kneecap after knee realignment surgery
This study looks at how well the kneecap joint holds up many years after a knee realignment surgery (high tibial osteotomy) for inner knee arthritis. If you had this surgery more than 5 years ago, you may be able to join a long-term checkup that uses X-rays and medical records to see how your knee is doing.
BolognaAges 18–65 - NCT06258161Recruiting
How spinal surgery affects balance and reach
This study looks at how adult spinal deformity surgery affects your ability to reach forward and balance. It compares the results of surgery with healthy adults to see if the surgery helps improve everyday movements.
Kansas City, KansasAges 18 years+ - NCT06258369Recruiting
How people with hip arthritis start walking
This study looks at how people with hip arthritis begin to walk and shift their weight from one leg to the other. It aims to understand movement changes before hip replacement surgery.
LilleAges 18 years+ - NCT06259006RecruitingPhase 3
Early Dexamethasone for Sydenham's Chorea in Children
This trial tests whether a short course of dexamethasone (a steroid tablet) can help children with Sydenham's chorea (movement tics after a strep infection) recover faster. The goal is to see if early treatment improves symptoms and reduces side effects compared to other treatments.
Darwin, Northern TerritoriesAges 4–17 - NCT06259890Recruiting
Salt intake and arthritis study
This study tests whether the amount of salt you eat affects inflammation and symptoms in people with certain types of arthritis (ankylosing spondylitis or psoriatic arthritis). You will be asked to follow a specific sodium diet and have some checkups to see how your arthritis responds.
BesançonAges 18–80 - NCT06260813Recruiting
Foot and ankle study for PTTD patients
This study looks at the foot and ankle of people with posterior tibial tendon dysfunction (PTTD) to understand how the tendon and foot structure change. It may help doctors plan better treatments.
Leuven, Vlaams-BrabantAges 18–75
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,838 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,965 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.