Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,773
- Phase 2214
- Phase 4199
- Phase 1182
- Phase 3138
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis173
- Rheumatoid Arthritis131
- Fibromyalgia104
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Degenerative Disc Disease39
- Psoriatic Arthritis39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital24
- Hacettepe University23
- Tanta University22
Where studies are running
- California206
- New York86
- Florida83
- Maryland76
- Arizona71
- Massachusetts71
- Texas66
- Alabama60
- Illinois50
- Pennsylvania47
Recruiting studies4,610 total
- NCT07031778RecruitingEarly Phase 1
Topical simvastatin to help jawbone healing after wisdom tooth removal
This study tests whether a simvastatin (a common cholesterol medicine) applied directly to the tooth socket after wisdom tooth removal can help your jawbone heal faster. If you need a lower wisdom tooth taken out and are generally healthy, you may be able to join.
Granada, GranadaAges 18–40 - NCT07028463Recruiting
Awareness and resources for fall risk in older ED patients
This study tests a program in the emergency department that helps older adults at risk for falls get connected to resources and support after they go home.
Aurora, ColoradoAges 65 years+ - NCT07030205Recruiting
Brain imaging study for women with osteoporosis
This study uses brain scans (MRI) to look at how the brain might be linked to bone health in women with osteoporosis. It compares women with osteoporosis to healthy women of the same age.
Clermont-FerrandAges 50 years+ - NCT07027306Recruiting
New score to guide treatment for osteoporotic spine fractures
This study tests a new classification system to help doctors decide the best treatment for spine fractures caused by osteoporosis. It aims to improve pain and mobility by matching treatment to fracture type.
San Francisco, CaliforniaAges 50 years+ - NCT07028034Recruiting
Six-minute step test for chronic back pain
This trial uses a simple step test to measure how chronic low back pain affects your daily function. It may help doctors better understand your condition without needing expensive equipment.
KırşehirAges 18–65 - NCT07027644Recruiting
Combined therapy for chronic neck pain relief
This trial tests whether combining a muscle-relaxation technique with cupping therapy is more effective than either alone for treating chronic neck pain caused by muscle knots in the upper trapezius. Participants must have had these knots for more than 6 months.
GizaAges 18–40 - NCT07032870Recruiting
Ultrasound reliability study in ICU patients
This study checks how reliably different physical therapists can measure muscles and nerves using ultrasound in patients who are awake and stable in the intensive care unit (ICU). It aims to improve muscle assessment techniques for critically ill adults.
Santiago, Metropolitan RegionAges 18 years+ - NCT07024095Recruiting
Breathing muscle training after back surgery for osteoporosis
This study tests whether a simple breathing-muscle training program can help people recover better after vertebroplasty surgery for a broken back caused by osteoporosis. It aims to improve your breathing strength and overall function.
Kayseri, KocasinanAges 50 years+ - NCT07033897Recruiting
Fall prevention program for people with disabilities
This study tests a program called HARP to help people with physical disabilities reduce falls and improve stability. You may join if you have had a disability for at least 5 years, live in St. Louis City, have trouble with daily tasks, and have fallen or feel unsteady.
St Louis, MissouriAges 45–64 - NCT07026552Recruiting
Ligament study for lumbar spinal stenosis
This study looks at the ligament in your lower back to understand how lumbar spinal stenosis develops. It involves analyzing tissue samples and may help find better ways to treat this condition.
Rome, RMAges 50–85 - NCT07026890Recruiting
Virtual reality for elderly with psychomotor disadaptation
This trial tests if using virtual reality can help older adults who have trouble moving and adapting to their surroundings (psychomotor disadaptation syndrome). It aims to improve their care while in a hospital geriatric unit.
DijonAges 65 years+ - NCT07026305Recruiting
Comparing surgical approaches for lumbar spinal stenosis
This study is comparing two surgical approaches for patients with lumbar spinal stenosis (narrowing of the lower spine). It aims to see if a less invasive surgery works as well as a more extensive procedure, which may help patients recover faster.
MadridAges 50 years+ - NCT07028723Recruiting
Proprioception and ligament injury risk in pivoting sports
This study tests whether your sense of body position and movement affects your risk of knee or ankle ligament injuries while playing sports like rugby, soccer, or handball. Participating could help identify ways to prevent these injuries.
MontpellierAges 14–25 - NCT06994546Recruiting
ArtiBest injection for knee osteoarthritis pain
This trial tests a new hyaluronic acid injection called ArtiBest for people with mild to moderate knee osteoarthritis who haven't gotten enough relief from other treatments like physical therapy or pain pills. It aims to see if the injection can reduce knee pain and improve function.
Kaohsiung CityAges 35–85 - NCT07020000Recruiting
Lumbar fusion with EARP nerve cuff electrode
This trial uses a medical device called the EARP Interbody System with a nerve cuff electrode during lower back fusion surgery. It collects real-world data to confirm the device is safe and works well for people having fusion between the second and fifth lumbar vertebrae.
Jacksonville, FloridaAges 22–80 - NCT07016802RecruitingPhase 1
Study of GenSci134 for growth hormone deficiency
This trial tests a new growth hormone treatment called GenSci134 in healthy adults and adults with growth hormone deficiency (AGHD). The goal is to see if it is safe and effective for people who need growth hormone replacement.
Beijing, Beijing MunicipalityAges 18–70 - NCT07017634RecruitingPhase 3
Novosis Putty for spine fusion in lumbar disc disease
This trial tests a new bone graft putty (Novosis Putty) used during a specific type of spine fusion surgery (TLIF) to treat a worn-out disc causing low back and leg pain. The goal is to see if it works as well as or better than current options.
Little Rock, ArkansasAges 21–80 - NCT07023094RecruitingPhase 4
Comparing two nerve blocks for kids' hip surgery
This trial tests two types of pain-relieving nerve blocks for children having hip surgery. One uses a PENG block with LFCB, the other an ESP block; the goal is to see which provides better pain control.
PoznanAges 2–16 - NCT07017686Recruiting
Reboot Study: Nerve stimulation for rheumatoid arthritis
This study tests a device that sends mild electrical pulses to the vagus nerve in the abdomen to treat rheumatoid arthritis. It is for people whose arthritis has not improved after trying multiple medications.
Fitzroy, VictoriaAges 18–75 - NCT07020312RecruitingPhase 2
Brain training to improve muscle recovery after joint surgery
This trial tests whether brain-computer interface training can help you regain muscle control more effectively after knee or hip surgery. It focuses on four common procedures and uses neurofeedback to optimize muscle activation during recovery.
Chicago, IllinoisAges 18 years+ - NCT07018960Recruiting
Chest wall repair with custom 3D-printed titanium implant
This study is testing a new way to repair large chest wall defects using a custom-made 3D-printed titanium implant. It may help people who need chest wall reconstruction after cancer surgery, a bad injury, or damage from infection or radiation.
Cruces, Basque CountryAges 18 years+ - NCT07021820Recruiting
New light-based imaging for centronuclear myopathy
This study tests a new type of imaging that uses light and sound to look at muscles in people with centronuclear myopathy. It may help doctors see muscle changes more clearly. It does not involve any treatment or medicine.
Erlangen, BavariaAges 2 years+ - NCT07018791RecruitingPhase 3
Art-based pain test for jaw joint disorder patients
This trial tests if using art can help measure pain in people with temporomandibular joint disorders (TMD). It may offer a new way to understand and manage your pain without surgery.
Jeddah, Mecca RegionAges 18 years+ - NCT07019727Recruiting
ACL injury prevention program for Czech athletes
This study tests a special training program designed to prevent ACL injuries in young athletes (ages 17-20) who play high-risk sports like soccer, basketball, or skiing. It aims to see if the program can reduce the chances of getting an ACL injury.
BrnoAges 17–20
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,529 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.