Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,773
- Phase 2214
- Phase 4199
- Phase 1182
- Phase 3138
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis173
- Rheumatoid Arthritis131
- Fibromyalgia104
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Degenerative Disc Disease39
- Psoriatic Arthritis39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital24
- Hacettepe University23
- Tanta University22
Where studies are running
- California206
- New York86
- Florida83
- Maryland76
- Arizona71
- Massachusetts71
- Texas66
- Alabama60
- Illinois50
- Pennsylvania47
Recruiting studies4,610 total
- NCT06871384Recruiting
Red wine diet for brain and body health in early elderly
This study tests whether a special diet including red wine can help improve thinking and movement in people aged 60–74. If you join, you would drink red wine as part of the diet and have your memory and physical abilities checked over time.
Logroño, SpainAges 60–74 - NCT06874413Enrolling by invitation
Exercise program for frail older adults before hernia surgery
This study tests whether a supervised exercise program before hernia repair surgery helps frail older adults recover better. The program includes physical exercises and breathing muscle training.
Greenville, South CarolinaAges 65 years+ - NCT06871735Recruiting
Collagen Material to Help Gum Heal After Bone Graft for Implants
This study tests a special collagen material used during bone graft surgery to help the gum close over the graft. It might help people who need extra bone before getting a dental implant.
Columbus, OhioAges 21–75 - NCT06876064Recruiting
Tracking people at risk for rheumatoid arthritis
This study follows different groups of people—from those at high risk of developing rheumatoid arthritis to those recently diagnosed—to learn more about the disease. By joining, you help researchers understand who gets RA and why, which may lead to earlier detection and better care.
Montpellier, HéraultAges 18–80 - NCT06878950Recruiting
Early feeding for babies with gastroschisis
This study tests whether starting feedings earlier than usual helps babies born with gastroschisis recover better. It aims to find a safer and more effective feeding plan for these newborns.
Los Angeles, CaliforniaAges birth–1 year - NCT06873113Recruiting
Blood flow therapy for shoulder pain
This study tests a new type of physical therapy that uses a blood pressure cuff to gently limit blood flow to the arm during exercise. It may help people with shoulder pain from subacromial impingement (a common cause of shoulder pain) regain function.
Gainesville, FloridaAges 18–50 - NCT06876350Recruiting
Wood cast vs. thermoplastic splint after thumb surgery
This trial compares two types of casts used after thumb joint replacement surgery to see which one works better for recovery. Participation lasts about 6 weeks.
Tampa, FloridaAges 18 years+ - NCT06877793Recruiting
Using dye imaging to diagnose severe flesh-eating infections
This trial tests a new way to quickly diagnose necrotizing soft tissue infections (NSTIs, also called flesh-eating infections) using a safe dye and a camera. If you are being checked for a possible NSTI, this could help doctors decide faster whether you have it and need treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT06875102Recruiting
Treating fatigue in Sjögren's syndrome with auricular stimulation
This trial tests three non-medication strategies for fatigue in Sjögren's syndrome, including a type of ear stimulation. It aims to find a better way to help people who have had fatigue for at least 6 months with no clear cause.
Saint-EtienneAges 18 years+ - NCT06873035Enrolling by invitationPhase 2/Phase 3
Infigratinib for children with hypochondroplasia
This study tests an oral medication called infigratinib in children with hypochondroplasia, a form of short stature. It aims to see if the drug can help improve growth and is for children who are still growing.
Oakland, CaliforniaAges 3–18 - NCT06869551RecruitingPhase 3
Testing a New Drug for Juvenile Psoriatic Arthritis
This study tests an investigational drug called Deucravacitinib to see if it can safely and effectively treat Juvenile Psoriatic Arthritis in children. You may be able to join if standard treatments haven't helped enough.
Lancaster, CaliforniaAges 5–17 - NCT06865105RecruitingPhase 2
Targeted treatments for active psoriatic arthritis
This study tests targeted medications for people with active psoriatic arthritis (PsA) who have already tried 1 or 2 other advanced treatments without success or couldn't tolerate them. The goal is to see if these newer options can better control joint pain and skin symptoms.
Huntington Beach, CaliforniaAges 18 years+ - NCT06867185Recruiting
Electrical stimulation for nerve healing after finger nerve repair
This trial tests whether giving a small electrical signal during surgery helps nerves in the finger heal better after they are repaired. It might help you regain feeling and movement faster.
Indianapolis, IndianaAges 18–80 - NCT06867107Enrolling by invitationPhase 2
Long-term follow-up study of SAT-3247 for Duchenne muscular dystrophy
This study follows people with Duchenne muscular dystrophy who were in an earlier SAT-3247 trial, or who meet certain other criteria, to see how the medicine works over a longer time. It aims to gather more safety and effectiveness information.
Los Angeles, CaliforniaAges 16–40 - NCT06866444Recruiting
Duloxetine and Fibromyalgia: How Your Body Processes the Drug
This study looks at how well duloxetine (Cymbalta) works in people with fibromyalgia. It may help doctors understand if people respond differently based on how their body breaks down the drug.
Salt Lake City, UtahAges 18 years+ - NCT06863129Recruiting
Surgery for thigh bone cancer: reconstruction vs. repair
This trial compares two types of surgery to fix the top part of the thigh bone that has been weakened or broken by cancer that spread from another part of the body. One surgery replaces the damaged area with an artificial joint, and the other repairs it using metal plates and screws.
Aurora, ColoradoAges 18 years+ - NCT06867003Recruiting
Exercise with or without bracing for office workers with kyphosis
This trial compares two treatment approaches for office workers with postural kyphosis (a rounded upper back that can cause pain). One group gets exercises alone, and the other gets exercises plus a posture brace. The goal is to find which works better for reducing pain and improving posture.
Malakand, KPKAges 30–45 - NCT06864351Recruiting
Study of a new thyroid dosing method for children
This study tests a new way to adjust thyroid medication doses for children with either congenital hypothyroidism or Graves' disease. It aims to help find the right dose more easily and improve treatment outcomes.
YerevanAges Up to 18 years - NCT06864780Recruiting
Posture exercises for forward head posture in device users
This trial tests if posture correction exercises can help fix forward head posture caused by heavy smartphone or laptop use. It is for people who spend at least 2-3 hours daily on their devices and have not had treatment for this condition before.
Malakand, KpkAges 18–40 - NCT06859385Enrolling by invitation
Standing up test for Parkinson's patients
This study tests a simple way to measure how well people with Parkinson's can stand up from lying down. It aims to see if the test is reliable and useful for tracking movement over time.
Gaziantep, Gazi̇azntepAges 40–65 - NCT06868147Recruiting
Long-term results of a second ACL reconstruction using a tendon graft
This study looks at people who had a second surgery to fix a torn ACL in their knee. The surgery used a special technique with a tendon from the Achilles. Researchers want to see how well the knee works and looks on X-rays at least 2 years after that surgery.
BolognaAges 18–50 - NCT06859801Recruiting
Bone pain study combining ablation and radiation
This study looks at combining two treatments for painful bone tumors that have spread from other cancers. It tests if using both treatments together provides better pain relief than either alone.
San Diego, CaliforniaAges 21 years+ - NCT06857708Recruiting
Wound dressings for necrotizing fasciitis wounds
This study tests two special wound dressings (Cytal® Wound Matrix and MicroMatrix®) to help heal wounds caused by a serious flesh-eating infection called necrotizing fasciitis. The goal is to see if these dressings improve healing and reduce the need for more surgeries.
Cleveland, OhioAges 18 years+ - NCT06864039Enrolling by invitation
Quality of life in treated congenital hypothyroidism
This study looks at the long-term quality of life for people who were diagnosed with congenital hypothyroidism at birth and started treatment within the first month of life. It aims to understand how early treatment affects their health and well-being as they grow up.
NaplesAges 16–21
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,529 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.