Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT06534554Recruiting
Improving gout care after an emergency room visit
This study looks at ways to improve how gout is managed after a visit to the emergency room. It aims to help you get better follow-up care and prevent future flares.
Birmingham, AlabamaAges 18–99 - NCT06536075Recruiting
Salivary gland function in Sjogren's syndrome
This study looks at how well your salivary glands work and if there is a connection with a special scan called sialoscintigraphy. It may help people with or without dry mouth symptoms and a Sjogren's diagnosis.
TaipeiAges 20–70 - NCT06536088Recruiting
Walk test for hip impingement patients
This study looks at how hip impingement affects walking. It may help doctors understand the link between symptoms and walking patterns before surgery.
AnkaraAges 18–75 - NCT06536166RecruitingPhase 2
Ruxolitinib for Inclusion Body Myositis
This trial tests the drug ruxolitinib (a JAK inhibitor) for people with inclusion body myositis (IBM), a progressive muscle disease. It aims to see if ruxolitinib can help slow muscle weakness and improve function.
Angers, FranceAges 45 years+ - NCT06538974Recruiting
Long-term use of an exoskeleton for leg weakness
This trial tests a walking device called an exoskeleton to help people with leg weakness or movement problems. It's designed to see if using the exoskeleton regularly over time can help improve walking or mobility.
ParisAges 18 years+ - NCT06539169Recruiting
Following people with rare diseases over time
This study follows people with rare diseases over time to learn more about how these conditions progress and how they are treated. Joining may help researchers understand your disease better and find better ways to care for others.
Los Altos, CaliforniaAges Any age - NCT06539793Recruiting
Nerve stimulation for fibromyalgia pain
This trial tests if a gentle nerve stimulation treatment can reduce pain and improve daily function in people with fibromyalgia. It aims to understand how treatment affects natural pain signals.
Sadat, MenoufiaAges 25–35 - NCT06541119Recruiting
Strengthening a leg muscle for bunion pain and function
This study tests whether strengthening a specific muscle on the outside of your lower leg can help reduce pain, improve foot alignment, and make it easier to walk and do daily activities if you have a bunion (hallux valgus).
GizaAges 18–60 - NCT06541548Recruiting
Bone health study for bone and muscle loss conditions
This study uses special imaging to compare bone structure in people with conditions that cause bone or muscle loss vs. those with back pain. It aims to better understand bone health in different diseases.
Saint-EtienneAges 18 years+ - NCT06542666Recruiting
Cognitive functional therapy for chronic shoulder pain
This trial tests a new approach called cognitive functional therapy for people with long-term shoulder pain. It combines mental strategies with gentle movements to help you manage pain and improve function.
João Pessoa, ParaíbaAges 18–60 - NCT06542809Recruiting
Growth hormone medicine change survey for kids
This survey asks children and teens currently using daily growth hormone shots if they would like to switch to a longer-acting medicine that requires fewer injections. Your answers will help doctors understand patient preferences.
Brussels, Woluwe-saint-lambertAges 1 day–18 years - NCT06543667RecruitingPhase 1
Stem cell eye drops for dry eye treatment
This trial tests a new eye drop made from stem cells to see if it can help relieve dry eye symptoms. It is for people with moderate to severe dry eye who haven't had recent eye surgery or used other eye drops.
TehranAges 18–70 - NCT06544343Recruiting
Remote monitoring for new immunosuppressive therapy
This trial tests whether regular remote check-ins can help manage chronic immunosuppressive medications. If you have an autoimmune condition like rheumatoid arthritis or lupus and are starting a new medicine such as methotrexate or a biologic, you may be eligible.
Perugia, PGAges Any age - NCT06546137Recruiting
Registry for inherited heart conditions in Brazil
This study is building a national registry in Brazil to learn more about inherited heart conditions and improve care. If you have a family-related heart disease, you may be able to join and help advance cardiovascular healthcare.
Rio Branco, AcreAges Any age - NCT06546345Recruiting
Study of KeriFlex® implant for hand joint replacement
This trial tracks how well the KeriFlex® implant works over time in people who need a finger joint replacement due to arthritis or injury. It aims to see if the implant helps reduce pain and improve hand function.
BesançonAges 18 years+ - NCT06547073Recruiting
Virtual reality vs traditional exercise for frozen shoulder
This study compares virtual reality training to standard exercise therapy for people with frozen shoulder. It aims to see if VR can be more effective in reducing pain and improving movement, offering a potentially more engaging treatment option.
GhentAges 18–70 - NCT06547684Recruiting
Shock wave therapy for foot stiffness after stroke
This trial tests whether shock wave therapy can help relax the tight calf muscles that cause foot drop after a stroke. It may help you walk better and reduce foot stiffness.
Vila-real, CastellonAges 18 years+ - NCT06548607RecruitingEarly Phase 1
CAR-T therapy for autoimmune diseases
This early-phase trial tests a new CAR-T cell therapy that targets CD19 or both CD19 and BCMA to treat several autoimmune diseases like lupus, scleroderma, and vasculitis. It aims to calm the overactive immune system with a single infusion of your own engineered cells.
Bengbu, AnhuiAges 18–70 - NCT06550596Recruiting
Amnion membrane for diabetic foot ulcers
This trial tests a wound covering made from donated amniotic tissue (dehydrated human amnion membrane) placed on a diabetic foot ulcer that isn't healing. It aims to see if adding this membrane to standard wound care helps the ulcer close faster.
Thousand Oaks, CaliforniaAges 18 years+ - NCT06551155Recruiting
Blood test to screen bone health and fracture risk
This study uses a simple blood test to look for early signs of bone loss and fracture risk. It's for people 40 and older who are either healthy, have early bone thinning, or have known osteoporosis.
BolognaAges 40 years+ - NCT06551389Recruiting
Lupus follow-up study at Brest Hospital
This study follows people with systemic lupus erythematosus (an autoimmune disease) who are seen in a special clinic. It aims to track their health over time.
BrestAges 18 years+ - NCT06552728Recruiting
Energy healing for fibromyalgia pain
This study tests if an energy healing treatment can help reduce pain in women with fibromyalgia. You will receive both real and sham (fake) energy healing sessions, and have MRI scans to see how your brain responds.
Irvine, CaliforniaAges 18–75 - NCT06553313Recruiting
Knee pain study for adults over 50
This study looks at proteins in the blood to understand knee health. It is for adults over 50 who do not have knee pain.
TaichungAges 50 years+ - NCT06553716Recruiting
Shoulder injection for frozen shoulder: a trial
This trial tests whether an ultrasound-guided injection of fluid and a steroid (triamcinolone acetonide) into the stiff shoulder joint can help improve range of motion and reduce pain in people with frozen shoulder (adhesive capsulitis).
Yinchuan, NingxiaAges 18–75
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.