Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT07237321Recruiting
Magnetic stimulation for flat feet: effects on arch and strength
This study tests whether magnetic stimulation of foot muscles can improve the arch of the foot and muscle strength in adults with flat feet. If you have flat feet without major leg or health problems, this trial may help find a new way to strengthen your feet.
Ljubljana, LjubljanaAges 18–50 - NCT07237568RecruitingPhase 3
Testing LNK01001 for active ankylosing spondylitis
This trial tests a new oral medication called LNK01001 for adults with active ankylosing spondylitis. It aims to reduce pain, stiffness, and inflammation when standard NSAID treatments no longer help.
BeijingAges 18 years+ - NCT07238413Recruiting
Comparing exercises and shockwave therapy for tennis elbow
This study compares two treatments for tennis elbow: scapular (shoulder blade) exercises and a type of shockwave therapy (ESWT). It aims to see which helps reduce pain and improve function better.
IstanbulAges 18–65 - NCT07238478Recruiting
Supplement for menopause quality of life in postmenopausal women
This trial tests a dietary supplement to see if it can improve menopause-related symptoms, like hot flashes and joint discomfort, in healthy postmenopausal women.
Harrison, New YorkAges 50–70 - NCT07238751Recruiting
Bowen technique and backward walking for knee osteoarthritis
This study tests whether the Bowen technique (a gentle hands-on therapy) combined with walking backward can improve hamstring flexibility and reduce pain in people with knee osteoarthritis. It may help if you have tight hamstrings and mild to moderate knee arthritis.
Islamabad, Punjab ProvinceAges 40–60 - NCT07239427Recruiting
Brain stimulation with pain coping for fibromyalgia
This study tests whether a gentle electrical brain stimulation method (tDCS), combined with a pain coping program, can help reduce fibromyalgia pain. It compares two groups to see if adding brain stimulation makes the coping program more effective.
Valladolid, ValladolidAges 18 years+ - NCT07241884Recruiting
Plantar fascia embolization with SakuraBead for heel pain
This trial tests a new treatment for plantar fasciitis using tiny beads (SakuraBead) that are injected to block abnormal blood vessels and reduce pain. It may help people with chronic heel pain that hasn't improved with other treatments.
Tashkent, UzbekistanAges 18–75 - NCT07242573Recruiting
Exercise and brain stimulation for fibromyalgia
This study tests if combining physical exercise with a gentle brain stimulation technique can improve pain, sleep, and fatigue in people with fibromyalgia.
Warsaw, Masovian VoivodeshipAges 20–80 - NCT07242729Recruiting
Compare two treatments for chronic heel pain from plantar fasciitis
This study compares two treatments—bone marrow aspirate and platelet-rich fibrin—to see which works better for long-lasting heel pain caused by plantar fasciitis. It may help if your pain has not improved with standard treatments like stretching or physical therapy.
São PauloAges 18–75 - NCT07243782Recruiting
Study of Cosentyx for skin and joint conditions in Korea
This study tracks how well Cosentyx works in real-world use for people with hidradenitis suppurativa, plaque psoriasis, or juvenile idiopathic arthritis. It helps doctors understand the medicine's long-term effects in Korean patients.
Seoul, SeoulAges 6–100 - NCT07244172Recruiting
Mud walking for kids with flexible flat feet
This study tests whether walking on mud can improve foot posture and balance in children with flexible flat feet. It may help strengthen the feet without surgery or special equipment.
Lahore, Punjab ProvinceAges 6–11 - NCT07245121Recruiting
Sugar water injections for chronic knee arthritis pain
This trial tests whether injecting a sugar-water solution around the nerves of the knee can reduce chronic pain from osteoarthritis. It is for people with long-term knee pain, stiffness, and cracking who have not had recent knee treatments or surgery.
Athens, AtticaAges 38 years+ - NCT07245303Recruiting
How Light Affects Pain in Chronic Pain
This study looks at how different kinds of light might change pain levels in people with chronic widespread pain, like fibromyalgia. By using brain scans (MRI), researchers hope to find new ways to manage pain without medication.
Chapel Hill, North CarolinaAges 18 years+ - NCT07245732RecruitingPhase 4
Steroid pills vs. shots for rheumatoid arthritis flares
This trial compares steroid pills to steroid shots for controlling sudden worsening of rheumatoid arthritis symptoms. It aims to find which method works better and is easier for you.
Toronto, OntarioAges 18 years+ - NCT07246096RecruitingEarly Phase 1
CAR-T cell therapy for autoimmune diseases
This trial tests a new CAR-T cell treatment for people with certain autoimmune diseases that have not responded to standard therapies. The treatment uses your own immune cells modified to target and attack disease-causing cells.
ShanghaiAges 18–70 - NCT07246122Recruiting
MRI-guided dynamic brace for scoliosis correction
This study tests a new MRI-guided brace system for teens with mild scoliosis (curves between 10 and 25 degrees). It aims to see if this dynamic brace is more comfortable and effective than traditional braces.
Tsim Sha Tsui, KowloonAges 10–16 - NCT07248072Recruiting
Nerve blocks for better recovery after knee replacement
This trial tests two types of nerve blocks—iPACK and BiFeS—to see if they help people feel better and recover faster after total knee replacement surgery. It compares adding these blocks to the usual spinal anesthesia.
ErzurumAges 18–75 - NCT07249060Recruiting
Interferon levels in cancer and autoimmune disease patients
This study looks at a protein called interferon in the blood of people with cancer who are starting immunotherapy, and people with certain autoimmune diseases (such as lupus, Sjögren's syndrome, scleroderma, or inflammatory myopathy). The goal is to compare interferon patterns and better understand immune responses.
Pamplona, NavarreAges 18 years+ - NCT07250581Recruiting
Disc repair surgery with removal for herniated disc: a comparison
This trial compares two types of surgery for a herniated disc in the lower back: one that only removes the damaged disc piece (discectomy), and another that also repairs the disc outer wall. It aims to see if adding the repair leads to better long-term results.
QingdaoAges 12–65 - NCT04864158Recruiting
Shoulder implant versus exercise program for damaged rotator cuff
This trial compares a shoulder implant (prosthesis) with an active exercise program for people whose rotator cuff has caused shoulder joint damage. The goal is to see which approach helps function and comfort better over time.
Aarhus NAges 60–85 - NCT07682090Recruiting
Nerve stimulation for fibromyalgia pain
This study tests a gentle nerve stimulation device worn near your ear to see if it can reduce fibromyalgia pain and improve how your body handles stress. It is a non-invasive treatment option that you receive while continuing your regular medications.
Rome, LazioAges 18–70 - NCT06059222RecruitingPhase 4
Optimizing Romosozumab for postmenopausal osteoporosis
This trial is testing a medicine called romosozumab to treat postmenopausal women with severe osteoporosis and a recent fracture. It aims to find the best way to use this drug to strengthen bones and prevent more fractures.
AarhusAges 50 years+ - NCT07576582Recruiting
Mud therapy for jaw joint pain
This trial tests whether a special mud treatment (peloid therapy) can reduce jaw joint pain and improve function in people with temporomandibular joint disorder. It is a non-drug approach that may help those who have had jaw pain for at least 4 weeks.
Uşak, MerkezAges 18–65 - NCT07127978Recruiting
Study of Givinostat in people with Duchenne muscular dystrophy
This study is for people with Duchenne muscular dystrophy (DMD) who are taking Givinostat, a daily oral medicine. Researchers will look at real-world data to see how the medicine works in everyday life, including lab results and how it's being used.
Little Rock, ArkansasAges 6 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.