Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT06490770Recruiting
Understanding knee pain and function
This study looks at how your knee joint works when you have pain or limited function. It uses MRI and electrical stimulation to learn more about cartilage and meniscus damage, which might help improve future treatments.
BolognaAges 18–60 - NCT07253493Recruiting
Bone loss and nerve activity study for postmenopausal women
This study looks at how bone loss in the hip might affect nerve signals to muscles. It compares postmenopausal women with weak bones (osteoporosis in the hip) to those with normal bone density.
Bahçelievler, IstanbulAges 18–65 - NCT07254117Recruiting
Study on gum tissue healing for severe gum disease
This trial tests whether special granulation tissue can help regenerate bone and gum support in people with severe gum disease who still have deep bone pockets after initial treatment. It may offer a better way to heal these defects.
RigaAges Any age - NCT07254351Recruiting
Limb length inequality study in children
This study looks at how a difference in leg length affects balance and movement in children aged 10 to 15. It uses a special low-dose X-ray (EOS) to take pictures of the child's spine and legs while they stand still.
BronAges 10–15 - NCT07254429RecruitingPhase 2
The Copenhagen Menopause Study for hot flash relief
This study tests a new treatment for women going through menopause who have frequent hot flashes. It aims to find a safe and effective way to reduce moderate to severe hot flashes.
HerlevAges 40–65 - NCT07255534Recruiting
Digital therapy for shoulder recovery after rotator cuff repair
This trial tests a digital app-based therapy to improve shoulder function after rotator cuff repair surgery. It uses your smartphone to guide your rehabilitation exercises at home.
Seoul, Republic of KoreaAges 19 years+ - NCT07256522Recruiting
Comparing treatments for trigger finger
This study compares three non-surgical treatments for a single trigger finger: a splint, paraffin wax, and a type of mud therapy. It aims to find which works best for improving finger movement and reducing pain.
Konya, KonyaAges 18–75 - NCT07258849RecruitingPhase 1
Study of LY4213663 in healthy people and rheumatoid arthritis
This study tests a new medicine called LY4213663 in healthy volunteers and people with rheumatoid arthritis. It aims to see if the medicine is safe and how the body handles it.
Anniston, AlabamaAges 18–75 - NCT07260747Recruiting
Virtual reality for foot health in sedentary students
This trial tests if virtual reality exercises can improve foot function, pressure, and balance in sedentary university students aged 18–25. It may help you understand how simple VR activities can benefit your feet and stability.
IstanbulAges 18–45 - NCT07261358Recruiting
3D exercises for teens with rounded upper back
This trial tests whether specific three-dimensional exercises (Schroth method) can improve trunk muscle endurance, sleep quality, and quality of life in adolescents with hyperkyphosis (excessive forward curve of the upper spine). If you have a child between 12 and 18 with a Cobb angle of 45° or more in the upper back, this study may help.
IstanbulAges 12–18 - NCT07261553Recruiting
Exercises at home for muscle and bone conditions
This study looks at how well people follow a home exercise program for muscle or bone problems. It aims to understand what helps or makes it hard to stick with the exercises.
Konya, KonyaAges 18 years+ - NCT07261644RecruitingPhase 3
Study of a new drug for active ankylosing spondylitis
This study tests a new medication (called 608) for adults with active ankylosing spondylitis (AS). It aims to see if the drug can reduce AS symptoms and improve quality of life.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07262294Recruiting
Deep breathing and core exercises for ankylosing spondylitis
This trial tests whether combining deep breathing with core stability exercises helps people with ankylosing spondylitis. It may improve symptoms and quality of life.
Banī SuwayfAges 25–45 - NCT07264101Recruiting
Balance test study for people with rheumatoid arthritis
This study tests a simple balance test (the Four Square Step Test) in people with rheumatoid arthritis. It aims to see how reliable and valid this test is for measuring your ability to move and stay steady.
MalatyaAges 18–65 - NCT07265557Recruiting
Comparing two pain plans after orthopedic surgery
This trial compares two different pain medication plans after major orthopedic surgery. It aims to find which plan helps you recover with less pain and fewer side effects.
Boston, MassachusettsAges 18 years+ - NCT07265999Recruiting
Severity factors of dermatomyositis in Caribbean patients
This study looks at what makes dermatomyositis more severe in people of Caribbean background living in Guadeloupe. By understanding these factors, doctors may better manage this rare muscle and skin disease.
Pointe-à-PitreAges 16 years+ - NCT07266753RecruitingPhase 4
Comparing oral antibiotics for leg and foot bone infections
This trial compares two common types of oral antibiotics to see which works better for bone infections below the knee. If you have a bone infection that needs at least 28 more days of treatment and you can take pills, this study may help find the best option for you.
Ottawa, OntarioAges 18 years+ - NCT07267156Recruiting
New Dressing After Bunion Surgery
This study tests a new type of bandage or dressing used after bunion (hallux valgus) surgery. It aims to see if this dressing works better than the usual dressing to help your foot heal.
Geneva, Canton of GenevaAges 18 years+ - NCT07267793Recruiting
Long-term study of CartiPRO for knee pain
This trial tests a treatment called CartiPRO for knee pain caused by osteoarthritis or cartilage damage. It looks at how well the treatment works over a long period and is for people who have a certain type of knee pain that hasn't improved with other treatments.
Seongnam-si, Bundang-guAges 19 years+ - NCT07268326Recruiting
Plant-based diet for rheumatoid arthritis
This trial tests whether a plant-based diet can help people with rheumatoid arthritis who have mild disease activity. You must have had RA for at least a year, be on stable medication, and not smoke or take prednisolone.
FrederiksbergAges 18 years+ - NCT07269925Recruiting
How different electrical frequencies affect muscle strength and pain
This study tests whether changing the electrical frequency during a type of nerve stimulation (percutaneous neuromodulation) can improve muscle strength and reduce pain sensitivity in people with a hidden muscle knot (trigger point) in the shoulder blade area.
Krakow, PolandAges 18–65 - NCT07270276Recruiting
Dry needling for shoulder muscle pain
This study tests if dry needling (a therapy that uses thin needles to release muscle knots) can help with shoulder muscle pain. It uses special tests to measure how the treatment affects your muscles and pain.
Boston, MassachusettsAges 18–80 - NCT07271771RecruitingPhase 4
Denosumab for muscle and insulin in diabetes
This study tests whether denosumab, a medication that strengthens bones, can also improve muscle strength and insulin sensitivity in postmenopausal women with type 2 diabetes who take metformin.
AarhusAges 40 years+ - NCT07273123Recruiting
Chewing gum and fatigue in jaw joint health
This study tests if chewing sugar-free gum for a while can affect how tired you feel and how your jaw muscles work. It compares people with and without jaw joint problems (TMJ disorders).
Milan, MilanAges 19–35
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.