Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT07342426RecruitingPhase 4
Laser therapy for tennis elbow
This trial tests high and low dose laser therapy for people with tennis elbow (lateral epicondylitis) that started less than three months ago. It aims to see if laser treatment can reduce pain and improve healing.
Kaohsiung CityAges 18 years+ - NCT07343752Recruiting
Blood flow restriction therapy for teen flat feet
This study tests whether adding a special blood-flow restriction technique to physical therapy helps teenagers with stiff, spasming flat feet more than physical therapy alone. It is for teens whose flat feet didn't get better with initial treatment.
AsyutAges 10–18 - NCT07344077Recruiting
One vs two wires for severe bunion surgery
This trial compares two ways of fixing the bone after bunion surgery (using one or two small wires). It's for people with severe bunions who haven't gotten better with non-surgical treatments.
Chon Buri, Changwat Chon BuriAges 18–60 - NCT07678112Recruiting
Trial of a device to keep rheumatoid arthritis in remission
This trial tests a medical device to help people with rheumatoid arthritis stay in remission while on biologic therapy. The goal is to see if the device can prevent flares and maintain disease control.
A Coruña, A CoruñaAges 18 years+ - NCT07678996Recruiting
Ozone injections for knee arthritis: finding the right dose
This study tests whether injecting ozone gas into the knee joint can reduce pain in people with knee osteoarthritis. It aims to find the best dose to help with pain during activities like walking.
KayseriAges 40–75 - NCT07449403Recruiting
Pain after hip replacement: testing a nerve block
This study tests a special numbing injection (called a PENG block) given around the hip joint to see how well it controls pain after hip replacement surgery. If you are having a hip replacement under spinal anesthesia and are in generally good health, this study may help find better ways to manage your post-surgery pain.
PoznanAges 65–100 - NCT07327892Recruiting
Comparing pain relief methods for hip surgery in older adults
This study compares three different ways to manage pain after hip surgery in older adults. One group gets a nerve block behind the hip, another gets the block plus a numbing injection around the joint, and the third gets only the numbing injection. The goal is to find the best method to reduce pain and help you recover more comfortably.
PoznanAges 65–100 - NCT07678034Recruiting
Long-term safety study of Tipmed shoulder replacement system
This study checks how safe and effective the Tipmed shoulder replacement system is over time. It is for people who already had this specific shoulder implant during surgery.
BalıkesirAges 18 years+ - NCT07677631Recruiting
Emotional allodynia in fibromyalgia: a questionnaire study
This study compares how people with fibromyalgia and those with other long-term pain conditions experience emotional pain (like feeling hurt by emotions). You will fill out a questionnaire about emotional sensitivity. The goal is to see if emotional allodynia (pain from emotions) is more common in fibromyalgia.
BariAges 18 years+ - NCT07581457Recruiting
Tranexamic Acid to Reduce Bleeding in Scoliosis Surgery
This study tests whether a medication called tranexamic acid can safely reduce blood loss during surgery to straighten the spine in teenagers with idiopathic scoliosis (a curved spine with no known cause). The goal is to help patients need fewer blood transfusions and recover better.
PoznanAges 10–18 - NCT07607964RecruitingPhase 1
ABBV-519 Study for Lupus or Rheumatoid Arthritis
This early-stage trial tests a new drug called ABBV-519 given as infusions or injections to treat systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA) in adults whose disease hasn't responded well to other treatments. Researchers will measure how safe the drug is, how it moves through your body, and whether it helps reduce symptoms.
Anniston, AlabamaAges 18–75 - NCT07581470Recruiting
Steroid Injection to Reduce Pain After Hip Replacement Surgery
This study tests whether adding a steroid medication (dexamethasone) through an IV line during hip replacement surgery reduces pain afterward. Researchers will compare three different doses to see which works best when combined with a nerve block (numbing medicine injected near the hip).
PoznanAges 18–100 - NCT07345949Recruiting
Study of skin inflammation in dermatomyositis
This trial looks at a type of skin inflammation called panniculitis that can happen in people with dermatomyositis. The goal is to learn more about this condition so that better treatments can be developed.
StrasbourgAges 1 year+ - NCT07346079RecruitingPhase 4
Corticotropin gel for acute gout flares
This study tests two doses of a medicine called Purified Cortrophin Gel for people having a gout flare that started in the last 5 days. It might be an option if other treatments haven't worked or aren't safe for you.
Boston, MassachusettsAges 18–90 - NCT07347041Recruiting
Trigger point injections for hip osteoarthritis pain
This study tests if injecting pain-relieving medication into tight muscle knots (called trigger points) can reduce hip pain from osteoarthritis. It is for people who still have pain despite trying other treatments.
Beijing, Beijing MunicipalityAges 45 years+ - NCT07347821Recruiting
Study of osteoarthritis in hip and knee replacement patients
This study looks at why osteoarthritis happens in the hip and knee by studying tissue samples taken during joint replacement surgery. If you are already scheduled for a first-time hip or knee replacement and have osteoarthritis, you may be able to join.
Ostrów Mazowiecka, Masovian VoivodeshipAges 18 years+ - NCT07347860RecruitingEarly Phase 1
Study of A-319 for active rheumatoid arthritis
This trial tests a new drug called A-319 for people with active rheumatoid arthritis (RA) that hasn't improved enough after trying other treatments. The goal is to see if A-319 can reduce joint pain, swelling, and inflammation.
Wuhan, HubeiAges 18–70 - NCT07347873Recruiting
Testing accuracy of exams for tennis elbow
This study compares several simple physical exams and an ultrasound test to see how well they can diagnose a common elbow problem called lateral elbow tendinopathy (tennis elbow). If you have pain on the outside of your elbow, this research might help confirm what is causing it.
Istanbul, MaltepeAges 18–60 - NCT07348419Recruiting
Pain blocks after single-level lumbar disc surgery
This study compares two types of pain-blocking injections (Quadro-Iliac vs Thoracolumbar Interfascial Plane Block) to see which provides better pain relief after a single-level lumbar disc surgery. If you are having this surgery, the trial may help you have less pain and use fewer pain medicines afterwards.
SamsunAges 18–70 - NCT07350395Recruiting
How steroids affect children with autoimmune conditions
This study talks to children and young people with autoimmune or inflammatory conditions (like juvenile arthritis) who have taken steroids in the past two years. It aims to understand how steroids impact their daily lives and feelings.
Bristol, North SomersetAges Up to 18 years - NCT07352254Recruiting
At-home medical care for housebound ME/CFS patients
This study is testing a way to improve medical care for people with ME/CFS (including post-COVID ME/CFS) who are mostly homebound. The goal is to see if bringing healthcare to your home helps you better manage your condition.
HanoverAges 18–69 - NCT07353619Recruiting
Stackable guides for all-on-6 upper jaw replacement
This trial tests a fully digital, guided surgery method for replacing all upper teeth with a fixed bridge on 6 implants (All-on-6). It aims to see if using custom 3D-printed guides and same-day temporary teeth works well for people with no remaining upper teeth.
Shibīn al Kawm, MenoufiaAges 40–70 - NCT07354542Recruiting
Relaxation therapy for pain and sleep after joint replacement
This trial tests if different relaxation methods, such as breathing exercises or virtual reality, can help reduce pain and improve sleep after hip or knee replacement surgery. It is designed for people who have had a joint replacement and are able to use a mobile phone or tablet.
Bartın, CenterAges 18 years+ - NCT07356115Recruiting
Pain patterns and pain location in muscle and sports clinics
This study looks at whether people's pain patterns—measured by a simple questionnaire called PainDETECT—are linked to where their pain is and what caused it. It may help doctors better understand and treat different types of pain.
IstanbulAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.