Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT07356206Recruiting
Dog-assisted therapy for fibromyalgia
This study tests whether spending time with a specially trained therapy dog can help people with fibromyalgia feel better and manage pain. You would attend 10 sessions and complete a few questionnaires.
GuimarãesAges 18 years+ - NCT07356401Recruiting
Cranial helmet treatment: parent expectations and satisfaction
This study looks at how well cranial helmets work for babies with flat head syndrome and how parents feel about the treatment and results.
Ankara, KeçiörenAges 3 months–1.5 years - NCT07358754Recruiting
S100B and BDNF levels in fibromyalgia
This trial measures two brain-related proteins (S100B and BDNF) in women with fibromyalgia compared to healthy women. It aims to find out if these proteins are linked to fibromyalgia symptoms, which could lead to better understanding or new treatments.
IstanbulAges 18–50 - NCT07359651Recruiting
Study on factors linked to death in severe tissue infections
This study looks at what factors are linked to higher risk of death in patients hospitalized with a severe, flesh-eating infection called necrotizing soft tissue infection (NSTI). It aims to help doctors better identify and treat these dangerous infections.
CagliariAges 18 years+ - NCT07360093Recruiting
Nerve block for chronic hip pain from osteoarthritis
This study tests a nerve block treatment for people with long-term hip pain from osteoarthritis who haven't gotten enough relief from other treatments. It aims to see if this procedure can help reduce pain.
AnkaraAges 18–80 - NCT07360626Recruiting
Exercise and Health Program for Textile Workers
This trial offers an exercise and health education program for textile workers at Lacor Textil. It aims to see if these activities improve your well-being and work health.
Zaragoza, AragonAges 18–65 - NCT07361094RecruitingPhase 1
CAR-T therapy for autoimmune disease after prior treatment
This trial tests a new CAR-T cell therapy that targets two proteins (CD19 and BCMA) on immune cells. It is for people with certain autoimmune diseases (like lupus or scleroderma) that have not responded well to standard treatments or have relapsed after prior cell therapy.
BeijingAges 18–70 - NCT07361198Recruiting
Knee artery embolization for arthritis pain
This trial tests a minimally invasive procedure to block small blood vessels in the knee, which may reduce pain from osteoarthritis. It's for people with ongoing knee pain even after standard treatments like medication or physical therapy.
Ústí nad LabemAges 40–80 - NCT07361328Recruiting
Ultrasound brain stimulation for fibromyalgia
This trial tests if a gentle ultrasound treatment aimed at the brain can reduce chronic pain in people with fibromyalgia. It may help those who haven't found relief from standard medications or physical therapy.
Salt Lake City, UtahAges 22–70 - NCT07362875Recruiting
Muscle imaging study for myotonic dystrophy
This study uses MRI scans to measure muscle changes in people with myotonic dystrophy (DM1 or DM2) and healthy volunteers. The goal is to find better ways to track the disease over time.
Winston-Salem, North CarolinaAges 18–65 - NCT07365033Recruiting
Exercise With Blood Flow Cuff vs Standard Training for Tennis Elbow
This study compares two exercise programs for long-term tennis elbow (pain for more than a year). One group does slow lowering exercises with a blood pressure cuff on the arm, and the other does standard resistance training.
Lahore, Punjab ProvinceAges 25–45 - NCT07366086RecruitingPhase 3
Long-term safety of romosozumab for osteogenesis imperfecta in children
This study follows children who previously received romosozumab in an earlier trial to check their long-term safety. It helps understand if the treatment's benefits last safely over time.
Indianapolis, IndianaAges 5–19 - NCT07367126Recruiting
Nerve pain in knee osteoarthritis: Pain and function study
This study looks at nerve-related pain in people with knee osteoarthritis and how it affects their pain level and daily function. It may help understand if nerve pain is a key factor in your knee OA symptoms.
IstanbulAges 40–70 - NCT07367789Recruiting
Predicting recovery after knee replacement using smart insoles
This study uses special insoles to measure how you walk before and after a knee replacement. The goal is to see if these measurements can help predict how well you will recover after surgery.
Yongin-si, Gyeonggi-doAges 19 years+ - NCT07367776Recruiting
Online education program for osteoporosis (RCT-PATOS)
This trial tests a digital education program for people with osteoporosis or osteopenia. It aims to help you learn more about your bone health and how to manage it, all from home using the 1177.se platform.
GävleAges 50 years+ - NCT07367971RecruitingPhase 1
ABP-671 interaction study for gout patients
This study tests how a new drug, ABP-671, interacts with allopurinol (a common gout medicine) in people with gout. It is looking for participants with normal or moderately reduced kidney function.
Cary, North CarolinaAges 18–75 - NCT07368751Recruiting
Vagus nerve stimulation for frozen shoulder treatment
This trial tests if stimulating the vagus nerve can help treat frozen shoulder. It might be an option if you have had shoulder pain and stiffness for at least 3 months and have not received prior treatment for this shoulder problem.
IstanbulAges 40–65 - NCT07368946Recruiting
Phosphate study for people with kidney disease
This study looks at how the body handles phosphate in people with chronic kidney disease. It may help researchers understand how to better manage phosphate levels to improve health.
Dallas, TexasAges 18 years+ - NCT07369934Recruiting
Virtual reality vs. manual therapy for shoulder pain
This study compares virtual reality exercises with a hands-on therapy technique (Mulligan mobilization) to improve shoulder posture and function in people with subacromial impingement syndrome. It aims to find which approach may relieve pain and help you move better.
GizaAges 30–50 - NCT07370480Recruiting
Knee Osteoarthritis and Thermal Spa Treatment Study
This trial tests whether a special spa treatment (thermal water therapy) can help with knee osteoarthritis pain and function. If you have moderate to severe knee OA and live near Enghien-les-Bains, France, this study may be a good fit.
Enghien-les-BainsAges 50–80 - NCT07371468RecruitingPhase 1
Study of an experimental drug for lupus, rheumatoid arthritis, and related conditions
This trial tests a new drug called GSK5926371 for people with certain autoimmune diseases that affect the joints, skin, and other tissues. It aims to see if the drug is safe and how well it works.
Buenos AiresAges 18–70 - NCT07373184Recruiting
Virtual planning for jaw joint replacement
This study looks back at past jaw joint (TMJ) replacement surgeries to see how virtual planning helped. If you already had this surgery at a specific hospital between 2010 and 2025, you might be included.
LundAges Any age - NCT07374107Recruiting
Patient insights for shaping myositis research
This study asks people with autoimmune muscle diseases (myositis) and their caregivers to share their experiences and insights. By joining, you help shape better research and care for myositis.
New Orleans, LouisianaAges 7 years+ - NCT07377058Recruiting
Tocilizumab study for anti-MDA5 positive dermatomyositis
This trial tests if adding the drug tocilizumab to standard therapy helps people with a rare type of dermatomyositis (anti-MDA5 positive) that often affects the lungs. It compares tocilizumab to a placebo to see if it can improve symptoms and lung function.
Beijing, Beijing MunicipalityAges 18–65
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.