Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT07447193Recruiting
Pain perception by gender in adults with scoliosis
This study looks at how men and women with scoliosis experience pain differently. It involves questionnaires and simple movement tests to understand pain patterns.
BakuAges 18–45 - NCT07447934Recruiting
Vibration therapy for leg muscle stiffness
This trial tests if gentle vibrations can reduce muscle stiffness (spasticity) in the lower leg after a neurologic condition like stroke or brain injury. You may join if you've had spasticity for at least 6 months and can stand with or without help.
New York, New YorkAges 18–85 - NCT07448883Recruiting
How well a Turkish scale measures spinal cord compression
This study tests a Turkish translation of a spinal cord function scale (mJOA) in people with degenerative cervical myelopathy. It helps doctors and patients better understand and track symptoms.
Buca, İzmirAges 18 years+ - NCT07449442Recruiting
Pain relief study after knee replacement surgery
This trial tests a special injection around the knee to improve pain control after knee replacement surgery. It may help reduce the need for strong pain medicines.
PoznanAges 65–100 - NCT07449468Recruiting
Nerve block to prevent confusion after hip replacement
This trial tests whether a nerve block (PENG block) can reduce confusion (delirium) after hip replacement surgery in older adults. It is for people 75+ scheduled for a first-time hip replacement under spinal anesthesia.
PoznanAges 75–100 - NCT07449806Recruiting
Comparing two bone graft materials for front tooth implants
This trial looks at two different types of bone graft material used when placing a dental implant right after removing a front tooth. It aims to see which one better maintains the thickness of the bone on the lip side of the implant.
AlexandriaAges Any age - NCT07450690Recruiting
Exercise training for muscle function in mitochondrial myopathy
This study tests whether exercise training can improve muscle function in adults with mitochondrial myopathy, a condition that affects how muscles produce energy. Participants will follow an exercise program to see if it helps their muscle strength and daily activities.
CopenhagenAges 18 years+ - NCT07451600Recruiting
TMS for spasticity and balance in multiple sclerosis
This study tests if transcranial magnetic stimulation (TMS) can help reduce muscle stiffness (spasticity) and improve balance in people with multiple sclerosis. TMS uses magnetic pulses to stimulate parts of the brain.
Ankara, YenimahalleAges 18–60 - NCT07455578RecruitingPhase 1
Study of S-4321 for people with autoimmune or immune diseases
This trial tests a new medicine, S-4321, for people with various autoimmune conditions like rheumatoid arthritis, psoriasis, eczema, or lupus. It aims to see if the drug is safe and can help control the overactive immune system.
Charlestown, New South WalesAges 18–75 - NCT07459400Recruiting
Mud therapy for young adults with scoliosis back pain
This study tests whether adding mud therapy (peloidotherapy) to standard scoliosis exercises helps reduce pain and improve function in young adults with mild to moderate scoliosis. It may be a good fit if you have idiopathic scoliosis and ongoing back pain.
Istanbul, GaziosmanpasaAges 20–40 - NCT07460076Recruiting
Immediate tooth implant with bone graft from the upper jaw
This trial tests placing a dental implant right after removing a tooth, using a small piece of bone from the back of your upper jaw to rebuild the gum area. It may help people who need a front tooth replaced and have a bone defect that requires this type of graft.
Ho Chi Minh City, Ho Chi MinhAges 18 years+ - NCT07461636Recruiting
Robotic-assisted screw placement in spine surgery
This trial studies how well a robotic system helps surgeons place screws in the spine. It may help make the surgery more precise and safer.
GothenburgAges Any age - NCT07463937Recruiting
Study of Methotrexate Injections in Rheumatoid Arthritis
This study looks at how well methotrexate injections work in people with rheumatoid arthritis. It is designed for patients who are starting or changing to this type of methotrexate treatment.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07464080Recruiting
Brain imaging study for knee replacement patients
This study uses advanced brain scans to understand how pain and recovery change after knee replacement surgery. It may help researchers develop better ways to manage pain after surgery.
Ottawa, OntarioAges 18 years+ - NCT07464821Recruiting
Lipid profile study in Noonan syndrome and related disorders
This study looks at cholesterol and fat levels in people with Noonan syndrome or related conditions. It aims to understand how these levels change with age, gender, and genetic cause.
AlessandriaAges 2–35 - NCT07465484Recruiting
Total knee replacement for bow-leg deformity
This study looks at how well total knee replacement works for people who have severe knee arthritis and a bow-leg (varus) deformity. It may help you if you have a lot of knee pain and are considering surgery.
MoscowAges 18 years+ - NCT07465991Recruiting
Online insomnia therapy for fibromyalgia and activity
This study tests if an online therapy program for insomnia (using cognitive behavioral therapy, or CBT) can help people with fibromyalgia sleep better and be more physically active. If you have fibromyalgia and trouble sleeping, this treatment may improve your pain and daily function.
OxfordAges 18 years+ - NCT07466823Recruiting
Spasticity Patterns and Quality of Life in MS
This study looks at patterns of muscle stiffness (spasticity) in people with multiple sclerosis and how these patterns affect daily life and well-being. It aims to better understand the link between spasticity and quality of life.
IstanbulAges 18 years+ - NCT07467187Recruiting
Home Ventilation with Tracheostomy in Denmark (2016–2025)
This study looks at people in Denmark who need a home ventilator through a tracheostomy. It aims to understand their care and outcomes over several years.
CopenhagenAges Any age - NCT07468461Recruiting
Camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome study
This study looks at children with CACP syndrome, a rare genetic condition, to learn more about how the condition affects the body over time.
BariAges Up to 18 years - NCT07472088Recruiting
Knee pain study using weight-bearing CT scans
This trial uses a special CT scan taken while you stand to see how the shape of your knee joint relates to your knee pain. It may help researchers better understand knee arthritis and front-of-knee pain.
Kansas City, KansasAges 18 years+ - NCT07472400Recruiting
Hip surgery recovery study for young adults with hip impingement
This study follows people before and after hip arthroscopy to treat femoroacetabular impingement (a condition where the hip bones pinch together). It measures strength, mobility, and daily function to see how recovery progresses over 6 months.
Sart Tilman, LiègeAges 18–40 - NCT07473414Recruiting
Knee tissue study for early osteoarthritis treatment
This trial studies knee tissue to find better ways to diagnose early osteoarthritis. It may help people who need a knee injection for pain relief.
NantesAges 18 years+ - NCT07473713RecruitingPhase 1
Veverimer for bone loss in adults with osteopenia
This study tests whether a medication called veverimer can help reduce bone loss in adults with osteopenia (early bone thinning) by lowering the acid load from their diet. Participants must be 50 or older, eat a typical Western diet, and have low bone density but not full osteoporosis.
Boston, MassachusettsAges 50 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.