Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT07474571Recruiting
Study of aging bones and joints using advanced scans
This trial uses scans like X-rays, CT, or MRI to study how bones and joints age. It aims to understand aging-related problems and may help develop better ways to detect or treat them.
BeijingAges 18 years+ - NCT07474662Recruiting
Online vs. in-person physiotherapy for jaw muscle pain
This trial compares online physiotherapy sessions with face-to-face visits to see which works better for treating jaw muscle pain (myalgia). It aims to find a more convenient way to get care for this common condition.
Budapest, Pest CountyAges 18 years+ - NCT07478172Recruiting
Electrical muscle stimulation exercise for neuromuscular disease
This study tests whether whole-body electrical muscle stimulation (using small electrodes on the skin) can help adults with certain neuromuscular diseases exercise and improve muscle strength. It may be an option if you can stand for about 15 minutes at a time and have some muscle strength left.
Columbia, MissouriAges 18 years+ - NCT07478224Recruiting
Blood flow restriction training for osteogenesis imperfecta type I
This study tests whether a special type of strength training, called blood flow restriction training, can improve muscle, bone, and quality of life in adults with osteogenesis imperfecta type I.
GhentAges 18–65 - NCT07478367Recruiting
Muscle weakness in hospitalized patients outside the ICU
This study looks at muscle weakness that can develop when you are in the hospital for an acute illness but not in the intensive care unit (ICU). It aims to understand how common this weakness is and what factors might be involved.
RozzanoAges Any age - NCT07481071Recruiting
Cyberchondria in teens with curved spine
This study looks at how teens with scoliosis (a curved spine) search for health information online and whether it causes extra worry. It may help doctors understand the emotional side of living with scoliosis.
IzmirAges 12–20 - NCT07481630RecruitingPhase 3
Testing a new medicine for weight loss and knee pain
This study tests if a new medicine called NNC0487-0111 can help people with extra weight and knee osteoarthritis lose weight and reduce knee pain. If you have knee pain most days and are willing to stop pain relievers for short periods, you may be able to join.
Phoenix, ArizonaAges 18 years+ - NCT07482332Recruiting
Core exercises for knee arthritis in women
This study tests if core stability exercises can reduce pain and improve function in women with knee osteoarthritis. It is designed for those who have not had recent physical therapy and can move their knees and hips freely.
SivasAges 45–65 - NCT07483216Recruiting
Exercise study for women with fibromyalgia
This trial tests a special type of strength exercise (isokinetic exercise) to see if it can help women with fibromyalgia feel better and move easier. It may be a good fit if you are generally stable on your current treatments and able to exercise safely.
Valladolid, ValladolidAges 18 years+ - NCT07484685Recruiting
Earlier implant placement after tooth preservation
This study tests if placing a dental implant sooner (about 6-8 weeks after tooth removal and socket preservation) works well with a specific implant type. It is for people who need to replace a single front tooth, canine, or premolar and have good bone and gum health.
Guayaquil, GuayasAges 18 years+ - NCT07485530Recruiting
Testing ultrasound strain tracking for physical therapy
This trial tests whether a new ultrasound method (speckle tracking) can measure soft tissue movement and strain to help guide physical therapy. It is looking for three groups: male pitchers, people with a foot tendon problem needing surgery, and people who had ACL knee surgery.
TaipeiAges 18–65 - NCT07486193Recruiting
Nunchaku exercise for frozen shoulder relief
This study tests whether practicing Nunchaku (a traditional martial arts tool) can help people with frozen shoulder, particularly those in the thawing stage. It aims to improve shoulder movement and reduce pain.
Hong KongAges 45 years+ - NCT06451757RecruitingPhase 3
A trial of sonlicromanol for mitochondrial disease
This trial tests a new medicine, sonlicromanol, for people with a specific type of mitochondrial disease (caused by the m.3243A>G mutation) who also have chronic fatigue and muscle weakness. The goal is to see if it helps improve symptoms and daily function.
Boston, MassachusettsAges 18 years+ - NCT05593640Recruiting
Thromboxane A2 and Knee Osteoarthritis Study
This trial is studying a substance called thromboxane A2 in people with knee osteoarthritis and joint swelling. It aims to help doctors better understand this condition and find new ways to treat it.
NiceAges 40 years+ - NCT07674407Recruiting
Fear of movement and physical function in back pain
This study looks at how fear of movement relates to physical function in people with long-term low back pain from a herniated disc. It may help understand how to improve daily activities.
IstanbulAges 18–65 - NCT06671483RecruitingPhase 3
Zasocitinib for psoriatic arthritis without prior biologic use
This trial tests an oral medication called zasocitinib for adults with psoriatic arthritis who have not tried biologic medicines before. It aims to see if the drug can improve joint pain, swelling, and skin symptoms.
Chandler, ArizonaAges 18 years+ - NCT07674134Recruiting
A Study of a JAK Inhibitor Pill for Rheumatoid Arthritis
This trial tests taking a JAK inhibitor (a type of pill that helps calm inflammation in rheumatoid arthritis) by mouth. It aims to see how well it works and if it's safe for people with RA who need this kind of medicine.
MonacoAges 18 years+ - NCT07673328Recruiting
Knee brace study for people with knee arthritis
This study tests a motorized knee brace for people with knee osteoarthritis. The brace helps support your knee as you walk, climb stairs, and go up and down ramps.
Ann Arbor, MichiganAges 18–85 - NCT07673809RecruitingPhase 1/Phase 2
Gene therapy trial for Duchenne muscular dystrophy in young boys
This trial tests a gene therapy called GNR-097 for boys with Duchenne muscular dystrophy (DMD). The therapy aims to help improve muscle function, and the study will check how safe and effective it is.
MinskAges 4–9 - NCT06998134Recruiting
Exoskeleton walking training for children and young adults
This trial tests whether a robotic leg exoskeleton can help improve walking in children and young adults with certain conditions (like cerebral palsy, muscular dystrophy, spina bifida, or spinal cord injury) or those with no walking issues. The goal is to find out if the exoskeleton is safe and effective for everyday use, especially in younger people who might lose the ability to walk as they get older.
Bethesda, MarylandAges 5–25 - NCT07486843RecruitingPhase 4
Preventing joint damage in early psoriatic arthritis
This trial tests if a treatment can prevent joint damage in people recently diagnosed with psoriatic arthritis. It compares a standard medication (methotrexate) with or without a newer biologic drug (adalimumab) to see which is better at stopping the disease from causing lasting harm.
Hong KongAges 18 years+ - NCT07488806Recruiting
Understanding Nemaline Myopathy Over Time (Spain)
This study follows people with nemaline myopathy over time to better understand how the disease progresses. It helps researchers learn more about the condition and plan future treatments.
BarcelonaAges Any age - NCT07489001Recruiting
Comparing opioid-free to standard anesthesia for back surgery
This study compares two types of anesthesia for lower back surgery: one that uses opioids and one that does not. The goal is to see which approach controls pain better with fewer side effects.
Istanbul, MaltepeAges 18–75 - NCT07489521RecruitingPhase 4
Arthrosamid vs. steroid for knee arthritis pain
This trial compares a new injection called Arthrosamid with a standard steroid injection to see which works better for knee arthritis pain over time. It may help you if you have knee arthritis and have not had recent injections or knee surgery.
Dublin, DublinAges 18–100
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.