Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT07640620Recruiting
How nerve sensitivity relates to heel pain
This study looks at whether people with plantar fasciitis (painful heel condition) have heightened nerve sensitivity, and how this connects to their symptoms. Researchers will compare your pain patterns and nerve responses to those of healthy volunteers to better understand what drives heel pain.
IstanbulAges 18–65 - NCT07642622Recruiting
Physical Activity Tracking With Wearable Technology for Spine Arthritis
This study tests whether wearing a Fitbit activity tracker and using a Google Health app can help people with axial spondyloarthritis (a type of spine arthritis) become more physically active. The goal is to see if this technology-based approach motivates people to exercise more, which may help reduce pain and improve their condition.
Seattle, WashingtonAges 18 years+ - NCT07642882Recruiting
Brain Stimulation for Fibromyalgia Pain Relief
This study tests whether a non-invasive brain stimulation treatment (rTMS) can reduce chronic pain in fibromyalgia patients. The treatment uses magnetic pulses to stimulate specific areas of the brain and may help relieve widespread pain.
Boulogne-Billancourt, Île-de-France RegionAges 18–80 - NCT07643441Recruiting
Testing digital scanning accuracy for full-arch dental implants
This study tests how accurately a digital scanning method (photogrammetry) can measure and plan treatment for patients with implant-supported full-mouth dental replacements. If you have multiple dental implants supporting a complete denture or bridge, researchers want to see if this scanning technique gives reliable measurements to help design better-fitting prosthetics.
Shibīn al Kawm, MenoufiaAges 18–50 - NCT07643896Recruiting
Blood test for pregnancy risk assessment using fetal cells
This study tests a new blood test that looks for fetal cells in your bloodstream to check your baby's health during pregnancy. The test is non-invasive—just a regular blood draw—and aims to help identify pregnancy risks earlier than traditional methods.
Phoenix, ArizonaAges Any age - NCT07644078Recruiting
Understanding Cavovarus Foot Deformity in Nerve Disorders
This study examines how nerve disorders like Charcot-Marie-Tooth disease cause a specific type of foot deformity (cavovarus feet, where the foot has a high arch and turned-in appearance). Researchers will either examine you directly or review your existing medical records to better understand this condition and how it affects people.
StanmoreAges 18 years+ - NCT07644624Recruiting
Sling vs. Dynamic Support After Shoulder Stabilization Surgery
This trial compares two different ways to support your shoulder after arthroscopic surgery to fix anterior shoulder instability (a condition where your shoulder joint slips forward). Researchers want to see which support method—a traditional sling or a dynamic stabilizer—helps you recover better with less pain and better function.
L'Hospitalet de Llobregat, CataloniaAges 18 years+ - NCT07645989Recruiting
Registry tracking long-term outcomes after MuseCell treatment
This registry follows patients who have received Dezawa MuseCells (a type of cell therapy) to understand how well the treatment works over 5 years. You'll complete online surveys about your health and progress periodically.
North Palm Beach, FloridaAges Up to 89 years - NCT07646262Recruiting
Gluten-Free vs Mediterranean Diet for Rheumatoid Arthritis
This study compares two eating patterns—a gluten-free diet and a Mediterranean diet—to see which might help reduce inflammation and improve symptoms in people with rheumatoid arthritis. You would follow one diet for the study period while your doctors monitor how you feel.
Gaziantep, ŞehitkamilAges 19–65 - NCT07646782Recruiting
Human Observatory Study: Aging and Longevity Research
This study observes how people age over time to better understand what helps people live longer and healthier lives. You'll share health information through surveys or online screening, and researchers will track changes in your health and wellbeing.
Boulder, ColoradoAges 18 years+ - NCT07651306Recruiting
Bone Loss After Stroke: New X-ray Detection Method
This study tests whether a new way of measuring X-rays can detect bone loss in the shoulder after a stroke. The research may help doctors identify patients at risk for fractures earlier.
IstanbulAges 18 years+ - NCT07651462Recruiting
Fasting Before Hip Surgery and Gut Health
This study tests whether fasting for 20 days before hip replacement surgery changes your gut bacteria in ways that might help your recovery. Researchers want to understand if this dietary approach affects how well you heal after the operation.
Berlin, State of BerlinAges 18–75 - NCT07651735Recruiting
Safety and Recovery Study of Tipmed Hip Replacement
This study tracks how well people recover after hip replacement surgery using the Tipmed hip implant system. Researchers will monitor your healing and implant performance over time to ensure the device works safely and effectively.
BalıkesirAges 18 years+ - NCT07652437Recruiting
Wearable device study for knee osteoarthritis walking
This study tests whether a wearable device can help people with knee osteoarthritis walk more easily and for longer periods. If you have knee pain or stiffness on most days and find walking difficult, this might help you improve your mobility.
Cambridge, MassachusettsAges 21–100 - NCT07653009Recruiting
Nerve stimulation for psoriatic arthritis pain
This trial tests whether a gentle electrical stimulation of a nerve in the ear can reduce pain and inflammation in people with psoriatic arthritis. If you have moderate to high disease activity despite stable treatment, you may be able to join.
IstanbulAges 18–65 - NCT07653295Recruiting
Study of Tıpmed revision hip replacement safety
This study follows patients who already had a revision hip replacement using the Tıpmed system. Researchers want to confirm the implant is safe and works well over time.
BalıkesirAges 18 years+ - NCT07653841Recruiting
Balance vs. strength training for knee osteoarthritis
This study compares two types of exercise programs (a balance-focused training and a progressive strengthening program) added to usual physical therapy. The goal is to see which works better for reducing knee pain and improving daily function in people with knee osteoarthritis.
Islamabad, ICTAges 40–70 - NCT07654647Recruiting
Custom 3D-printed implants for facial bone repair
This trial tests personalized 3D-printed titanium implants to fix facial bone problems, like from cysts, tumors, or birth defects. It's for people who need a custom-shaped implant to improve their face's look and function.
LatakiaAges 18–60 - NCT07657598Recruiting
Fluid monitor for children having skull surgery
This study checks if a special monitor (called Pleth Variability Index) helps doctors manage fluids better during surgery for children with craniosynostosis. It may lead to safer recovery for your child.
Istanbul, BasaksehirAges Up to 6 years - NCT07660029Recruiting
Smart home blood test study for rheumatoid arthritis
This study tests a smart home blood collection platform for people with rheumatoid arthritis. It aims to make remote monitoring easier by allowing you to collect blood samples at home using a smartphone or tablet.
LondonderryAges 18 years+ - NCT07661589Recruiting
Blood transfusion risks and cell saver in children's scoliosis surgery
This trial looks at how often blood transfusions are needed during scoliosis surgery in children and whether using a device that recycles lost blood (cell saver) can reduce that need.
TunisAges Up to 17 years - NCT07661784Recruiting
Saliva tests to track gum disease
This study looks at whether substances in your saliva can show if gum disease is getting worse. It might help find a simple way to monitor gum health without needles or X-rays.
IspartaAges 18–65 - NCT07664605Recruiting
Comparing two bone grafting methods for dental implants
This trial compares two surgical techniques for building up narrow jawbone before placing a dental implant. It may be an option if you have mild to moderate bone loss in your jaw.
CairoAges 20–75 - NCT07665021RecruitingPhase 1/Phase 2
Gene therapy for children with severe bone disease
This trial tests a gene therapy that uses a child's own stem cells to treat autosomal recessive osteopetrosis (a genetic bone disease). It aims to improve bone health and reduce complications like fractures and vision loss.
Milan, ItalyAges 4 weeks–2 years
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.