Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT07665424Recruiting
Study of a bone filling device for spine fractures
This trial tests a device called Vessel-X to treat broken vertebrae (spine bones) caused by osteoporosis or injury. It aims to see if the device is safe and helps stabilize the spine.
TaipeiAges 40–95 - NCT07666126Recruiting
Uric acid and gum bone health study
This study looks at whether high uric acid levels affect the bone around your teeth. If you are between 18 and 65, have at least 20 natural teeth, and are either healthy or have high uric acid and gum disease, this trial may be for you.
RizeAges 18–65 - NCT07666360Recruiting
Jaw pain study: factors that predict TMD severity
This trial looks at how your head, neck, and jaw work together to understand why some people have more severe jaw joint (TMD) pain. If you have jaw pain, the findings may help researchers identify better treatments.
AnkaraAges 18–55 - NCT07666347Recruiting
Botox and Hyaluronic Acid Injections for Knee Osteoarthritis
This study tests if injecting Botox and hyaluronic acid into the knee joint can reduce pain and improve function in people with advanced knee osteoarthritis. It compares this combination to a standard treatment.
Tanta, El-GharbiaAges 50 years+ - NCT07671482Recruiting
Kinesio vs McConnell taping for knee pain relief
This study compares two types of taping (Kinesio and McConnell) to see which works better for people with pain behind the kneecap (patellofemoral pain syndrome). You may help researchers learn how to best relieve knee pain during daily activities.
Beirut, BeirutAges 18–50 - NCT07662993Enrolling by invitation
Cognitive skills in fibromyalgia study
This study looks at how fibromyalgia affects thinking skills like memory and focus. It aims to understand which factors are linked to these cognitive changes in women with fibromyalgia.
DenizliAges 18–65 - NCT07652372Enrolling by invitationPhase 1
Injectable RAB001 for knee osteoarthritis (Phase 1b)
This trial tests an injectable medication called RAB001 for people with knee osteoarthritis that hasn't improved with other treatments. The goal is to see if it's safe and helps reduce pain.
Beijin, BeijinAges 40–75 - NCT07632729Enrolling by invitation
Knowledge of Results Training for Shoulder Pain
This study tests whether giving you immediate feedback during shoulder exercises helps reduce rotator cuff-related shoulder pain. The rotator cuff is a group of muscles and tendons in your shoulder; this trial focuses on people with impingement, bursitis, tendon inflammation, or small tears.
Ankara, SıhhıyeAges 18–35 - NCT07615361Enrolling by invitation
Tooth Graft and Laser Therapy for Dental Implants
This study tests whether material from extracted teeth, combined with low-level laser treatment, can help bone heal better before dental implants are placed. The goal is to improve implant success and reduce bone loss after tooth removal.
Istanbul, UskudarAges 18–65 - NCT07614672Enrolling by invitation
Instrument-Assisted vs. Manual Massage for Heel Pain
This study compares two hands-on treatment techniques for plantar fasciitis—a common cause of heel pain. Researchers want to see which approach works better to reduce pain and improve how you walk.
Islamabad, FederalAges 19–64 - NCT07599059Enrolling by invitation
AI-assisted ultrasound therapy for frozen shoulder
This trial tests a new AI-assisted ultrasound therapy for frozen shoulder (adhesive capsulitis). It aims to see if this non-invasive treatment can help improve shoulder stiffness and movement without the need for surgery or injections.
TaipeiAges 18 years+ - NCT07590882Enrolling by invitation
Sports Recovery After Hip Realignment Surgery
This study follows patients who had hip socket realignment surgery (PAO) to understand how well they return to sports and physical activities. Researchers will review medical records from the past 7+ years to learn what helps patients get back to the sports they love.
BolognaAges 12–40 - NCT07578168Enrolling by invitation
Kinesio Tape for Rotator Cuff Shoulder Pain
This study tests whether kinesiology tape (a special stretchy tape applied to the skin) can reduce pain and improve function in people with rotator cuff syndrome, a common shoulder condition. You'll be randomly assigned to receive the tape or a control treatment and tracked over several weeks.
Kırşehir, MerkezAges 18–65 - NCT07573761Enrolling by invitation
Tooth Grafts to Help Bone Grow for Dental Implants
This trial tests whether material made from extracted teeth can help bone regrow in the jaw after tooth removal, so you can get a dental implant. Researchers will compare this new approach to see if it works better for rebuilding bone in areas where teeth need to be replaced.
Istanbul, UskudarAges 18–65 - NCT07566936Enrolling by invitation
Digital vs. Traditional Splints for Jaw Joint Disorders
This study compares two types of custom-made jaw splints—one designed using digital technology and one made the traditional way—to see which better relieves jaw pain and improves mouth opening in people with temporomandibular disorder (TMD), a common condition affecting the jaw joint.
Islamabad, IslamabadAges 18–40 - NCT07565272Enrolling by invitation
Virtual Reality Game for Duchenne Muscular Dystrophy Arm Strength
This study tests a video game played in virtual reality to see if it helps people with Duchenne muscular dystrophy (a muscle-weakening condition) use their arms and hands better. Researchers want to understand if the game is easy to use and enjoyable.
IstanbulAges 7 years+ - NCT07563842Enrolling by invitation
Defining Abdominal Pressure Complications After Surgery
This study is updating medical definitions for a serious condition called abdominal compartment syndrome—where pressure builds up in the belly after surgery or critical illness. The research involves expert doctors and patients who have experienced this condition, working together to clarify what it is and how to recognize it.
LublinAges 18 years+ - NCT07543302Enrolling by invitation
Can Ear Nerve Stimulation Reduce Inflammation in Duchenne Muscular Dystrophy?
This trial tests whether gently stimulating a nerve in the ear can lower inflammation levels in boys with Duchenne muscular dystrophy (DMD). The goal is to see if this non-invasive approach might help slow disease progression or ease symptoms.
StockholmAges 5–17 - NCT07536672Enrolling by invitation
Understanding Pain and Sexual Health in Chronic Pain
This study helps develop a questionnaire (survey) that measures how chronic pain affects sexual health and relationships. If you have long-term pain and a stable relationship, your feedback could help doctors better understand and support patients like you.
Kütahya, KütahyaAges 18 years+ - NCT07516574Enrolling by invitation
Exercise program before scoliosis surgery in teens
This trial tests whether doing special exercises before spine surgery helps teens with adolescent idiopathic scoliosis (a sideways curve of the spine). The goal is to see if pre-surgery exercise improves how patients recover and feel after surgery.
Edmonton, AlbertaAges 10–18 - NCT07514208Enrolling by invitation
Headache Sensitivity and Pain Testing Study
This study examines how sensitive the skin and tissues around the head are in people with migraines or tension headaches. Researchers will perform gentle touch and pressure tests to understand pain patterns, which may help improve headache treatment in the future.
Barcelona, BarcelonaAges 18 years+ - NCT07504562Enrolling by invitationPhase 2
Ejiao Paste for Knee Osteoarthritis Pain
This trial tests a traditional Chinese medicine patch called Knee Pain Ejiao Paste for knee osteoarthritis pain. It aims to see if the paste reduces pain and improves function compared to a placebo.
Shanghai, Shanghai MunicipalityAges 40–75 - NCT07486609Enrolling by invitation
Comparing tests for jaw joint pain diagnosis
This study compares two different ways to diagnose jaw joint (TMJ) problems: a jaw-motion analyzer and an MRI. It aims to see which method is more accurate for people with ongoing face or jaw pain.
CairoAges 18–50 - NCT07478861Enrolling by invitation
Vibration training for seniors with knee arthritis and obesity
This study tests whether whole-body vibration training can help older adults who have both severe knee arthritis and obesity. It aims to improve strength, mobility, and quality of life.
Banī SuwayfAges 60–75
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.