Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07688863Enrolling by invitation
Comparing breathing muscle training methods for heart failure
This trial compares two different types of breathing muscle training to see which works better for people with heart failure and weak breathing muscles. You may join if you have heart failure with reduced pumping ability and are stable overall.
Viña del Mar, ValparaisoAges 18 years+ - NCT07693998Enrolling by invitation
Pain education class for fibromyalgia or chronic back pain
This trial tests a class to help people with fibromyalgia or chronic low back pain learn about their pain and how to manage it. It might help you feel better and understand your pain.
Valencia, ValenciaAges 18 years+ - NCT07696923Recruiting
Treating frozen shoulder with microembolization or steroid injection
This trial compares two treatments for frozen shoulder: a new procedure that blocks tiny blood vessels (TAME) and a steroid injection. You must have had shoulder pain for at least a month and be willing to do physical therapy.
TaipeiAges 18–80 - NCT07689747Recruiting
Brain training and ankle tests for athletes with weak ankles
This study tests if adding a special computer-based brain training activity to regular ankle function tests can help teenage and young adult athletes who have ongoing ankle problems. If you are a licensed football, basketball, or volleyball player aged 16–25 with chronic ankle instability for at least a year, you may be eligible.
Istanbul, SarıyerAges 16–25 - NCT07688876Recruiting
Comparing two treatments for long-term heel pain
This trial tests two minimally invasive procedures—pulsed radiofrequency and a dextrose injection—to see which better relieves chronic heel pain from plantar fasciitis that hasn't improved with other treatments.
AnkaraAges 18–70 - NCT07694882Recruiting
Gentle pressure techniques for chronic neck pain
This study tests two different types of gentle pressure techniques (myofascial release) to see which one helps relieve long-term neck pain and improve everyday function. It is for people with chronic neck pain that isn't caused by a specific injury or disease.
Famagusta, HatayAges 18–45 - NCT07688902Recruiting
Comparing two injection methods for partial rotator cuff tears
This study compares two ways of injecting a sugar-water solution (5% dextrose) into the shoulder to treat partial rotator cuff tears. It may help reduce pain and improve shoulder function without surgery.
AnkaraAges 18–75 - NCT06175884Recruiting
Communication skills for chronic muscle and joint pain
This trial tests how a physical therapist's communication style affects pain and function in people with long-term muscle or joint pain. Participants will fill out questionnaires and watch a video to see if better communication improves outcomes.
LamiaAges 18–65 - NCT05648474Recruiting
Nerve monitoring during a low-back fusion surgery
This study tests whether special nerve monitoring during a low-back fusion helps make surgery safer and the results easier to judge. It’s for people having a specific type of low-back fusion on one or two levels.
Carlsbad, CaliforniaAges 18 years+ - NCT06653998Recruiting
Early movement and rehab in ICU patients
This study tests whether starting physical therapy and movement early is safe and possible for patients in the intensive care unit. It aims to improve recovery for people who are stable enough to participate.
Bogotá, Bogota D.C.Ages 18 years+ - NCT06426875Recruiting
Isometric training for shoulder pain in bowlers
This trial tests if isometric muscle training (holding still muscle contractions) can reduce shoulder pain and improve function and bowling performance in male bowlers. It may help if your pain affects your game and causes emotional distress.
Rawalpindi, Punjab ProvinceAges 18–30 - NCT06656182Recruiting
Mobilization techniques for scapulocostal syndrome
This trial tests two types of gentle joint movements (SNAGs and scapular mobilizations) to see if they reduce pain and improve shoulder and neck movement in people with scapulocostal syndrome. If you have chronic neck pain and trouble lifting your arm overhead, this study may help.
Rawalpindi, Punjab ProvinceAges 18–40 - NCT04934839Recruiting
Gait study comparing prosthetic walking types in adults
This study compares how people walk using an osseointegrated prosthesis (a prosthesis connected to the bone) versus a traditional socket prosthesis. It may help researchers understand which option works better for walking balance, comfort, and function.
Milan, MIAges 18 years+ - NCT05844098Recruiting
Fixing a shoulder AC joint injury with or without extra pins
This trial compares two surgical options for a recent shoulder AC joint injury: one method uses arthroscopy-assisted stabilization alone, and the other adds an extra K-wire (small metal pin) for fixation. The goal is to see which approach leads to better healing and shoulder recovery.
Chon BuriAges 18–45 - NCT06482203Recruiting
Comparing exercises for round upper back posture
This trial compares two types of exercises—endurance training for back muscles versus shoulder blade mobilization—in people with a hunched upper back (thoracic kyphosis) and mild back pain. It will help determine which approach is more effective.
Peshawar, Khyber PakhutunkhuwaAges 20–40 - NCT06650228Recruiting
Heart risks and healthy habits in ankylosing spondylitis
This study looks at how heart health risks and healthy lifestyle habits (like diet, exercise, and not smoking) relate to people with ankylosing spondylitis. It may help you understand how to better manage your overall health.
KırşehirAges 18–65 - NCT06658327Recruiting
Stretching for knee arthritis in postmenopausal women
This study compares two types of stretching to see which better reduces pain and improves movement in postmenopausal women with knee osteoarthritis. It may help you find a simple, drug-free way to manage your symptoms.
Lahore, Punjab ProvinceAges 50–65 - NCT07683650Recruiting
Hyaluronic acid and platelet gel for jaw joint disc pain
This study tests a mixture of hyaluronic acid (a natural lubricant) and platelet-rich fibrin (from your own blood) injected into the jaw joint to see if it helps people with a misaligned jaw disc and pain. It may improve jaw movement and reduce discomfort.
Al MansurahAges 18–45 - NCT07682051Enrolling by invitation
Resistance training for patellar tendon pain
This study tests whether resistance training can improve the health of the patellar tendon in people with patellar tendinopathy (pain at the knee cap). It may help you recover strength and reduce pain over time.
Graz, StyriaAges 18–50 - NCT07686809Recruiting
Leg therapy for children with one-sided weakness
This study tests a new leg exercise program to help children with hemiplegia walk better. The therapy may improve balance and movement in the affected leg.
CairoAges 6–8 - NCT07681661Recruiting
Massage Gun vs Deep Massage for Shoulder Knots
This study compares using a handheld massage device (like a massage gun) with deep pressure massage to treat painful knots in the upper shoulder muscle. It may help people with moderate to severe neck or shoulder pain who have not had recent treatment.
IslamabadAges 24–45 - NCT07681804Recruiting
Steroid vs Sugar-Water Injection for Trigger Finger
This study compares two common treatments for trigger finger: a steroid injection (betamethasone) and a sugar-water (dextrose) injection. The goal is to see which one works better to relieve finger locking and pain.
IstanbulAges 18–75 - NCT07682090Recruiting
Nerve stimulation for fibromyalgia pain
This study tests a gentle nerve stimulation device worn near your ear to see if it can reduce fibromyalgia pain and improve how your body handles stress. It is a non-invasive treatment option that you receive while continuing your regular medications.
Rome, LazioAges 18–70 - NCT07685418Recruiting
Pressure therapy and home exercises for neck pain
This trial tests whether a hands-on technique called ischemic compression (applying gentle pressure to trigger points) plus home exercises helps relieve long-term neck pain that has no specific medical cause.
Istanbul, BakırköyAges 17–65
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.