Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,422 recruiting studies in this area right now.
By phase
- Not applicable9,759
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama210
- Illinois189
- Pennsylvania178
Recruiting studies12,420 total
- NCT04007380Recruiting
Sleep problems after spinal cord injury study
This study looks at how sleep-disordered breathing (breathing problems during sleep) affects mood, thinking, and behavior after a spinal cord injury. It may help researchers understand the impact of these sleep breathing issues and guide better support for people after injury.
Toronto, OntarioAges 18 years+ - NCT04010214Recruiting
Study of cerebellar ataxia in Southeast China
This is an observational study that follows people with cerebellar ataxia, their relatives, and healthy volunteers to learn more about the condition. It may help researchers better understand the causes and patterns of cerebellar ataxia over time.
Fuzhou, FujianAges Any age - NCT04007432Recruiting
Testing nighttime low-oxygen levels after hip fracture surgery
This study checks how often older adults get low oxygen during the night after hip fracture surgery. It may help doctors better monitor and improve care during hospital recovery.
ParisAges 70 years+ - NCT04008329Recruiting
Study of people with amyotrophic lateral sclerosis
This study follows people living with amyotrophic lateral sclerosis (ALS) over time. It may help researchers better understand ALS and track changes that could guide future treatments.
Fuzhou, FujianAges Any age - NCT04010604Recruiting
Study of spinal muscular atrophy in patients and carriers
This is a long-term observation study that follows people affected by spinal muscular atrophy (SMA), people who carry the SMA gene but have no symptoms, and families of people with SMA. It helps researchers better understand SMA and related genetic status, which can support future treatment planning.
Fuzhou, FujianAges 1 week–70 years - NCT04010188Recruiting
Study comparing people with Charcot-Marie-Tooth and healthy controls
This study follows people who have Charcot-Marie-Tooth disease (CMT) and compares them with people without it. It aims to better understand CMT, using both clinical symptoms and genetic test results, which may help future care.
FuzhouAges Any age - NCT04012671Recruiting
Study of Duchenne muscular dystrophy in children and carriers
This is a research study that follows people with Duchenne muscular dystrophy and female genetic carriers to better understand the condition. It may help researchers measure health patterns over time, which can support future treatments.
FuzhouAges 2 years+ - NCT04011566Recruiting
Testing a shunt sensor in people with symptom-free hydrocephalus shunts
This study checks how well a device called ShuntCheck works for monitoring a ventriculoperitoneal (VP) shunt in people who feel okay (no symptoms) with normal pressure hydrocephalus. It may help improve future shunt checks during routine care.
Tampa, FloridaAges 40 years+ - NCT04012905RecruitingPhase 3
Compare two steroid taper schedules for giant cell arteritis
This Phase 3 study compares how two standard steroid dose-reduction (tapering) schedules work for people with giant cell arteritis. It aims to see which taper approach controls the disease while reducing problems from long-term steroid use.
CaenAges 50 years+ - NCT04012411Recruiting
Testing brain fluid biomarkers in Huntington’s disease
This study looks at specific “biomarkers” (measurable signs) found in cerebrospinal fluid, to better understand Huntington’s disease. The results may help researchers track the disease and improve future tests or treatments.
MontpellierAges 18 years+ - NCT04012658Recruiting
Study of people with Wilson disease genes and family members
This study follows people who have the genetic cause of Wilson disease, including people who feel well and family members. Researchers want to better understand Wilson disease and what to watch for over time.
FuzhouAges Any age - NCT04014413Recruiting
Fecal transplant for gut and immune-related conditions
This trial studies whether fecal microbiota transplantation (FMT)—a medical procedure using stool from a screened donor to restore gut bacteria—can improve safety and outcomes for people with certain bowel, immune, and metabolic conditions. It may help if your symptoms are thought to be related to an unhealthy gut microbiome, though eligibility is broad and depends on specific safety factors.
Hong Kong, ShatinAges Any age - NCT04025398Recruiting
Computer training to improve thinking skills in adults with disability
This study tests whether a computer-based “cognitive remediation” program can improve thinking and daily functioning in adults with mild to moderate intellectual disability. It may help your attention and social thinking, alongside usual care.
Lyon, Auvergne-Rhône-AlpesAges 18–45 - NCT04026386Recruiting
Early intervention program for preschool children with developmental delays
This trial tests a structured, center-based early intervention program for preschoolers with developmental disorders. It may help children build skills and support development through guided activities and testing at the research site.
Stanford, CaliforniaAges 2–5 - NCT04031950Recruiting
Testing a sleep sensor for children suspected of sleep apnea
This study tests a child sleep “sensor” device in kids who have been referred to a sleep clinic because sleep apnea is suspected. It may help doctors diagnose sleep problems more easily using extra information from the sensor.
SheffieldAges 1–18 - NCT04032379Recruiting
Study biomarkers to predict outcomes in idiopathic intracranial hypertension
This study looks at body measurements (“biomarkers”) to help doctors diagnose idiopathic intracranial hypertension (IIH) and predict how it may go over time. If you’re an adult with a doctor’s concern for IIH, you may be asked to provide health information and possibly samples for testing.
Copenhagen, GlostrupAges 18 years+ - NCT04032990Recruiting
Testing a skin-based nerve stimulation for kids’ arm function
This trial studies whether a painless, skin-based treatment (stimulation over the spine) is safe and feasible to improve arm and hand function in children with a spinal cord injury. It’s mainly designed to see if the approach can be done safely and whether it may help upper-limb skills.
Louisville, KentuckyAges 4–18 - NCT04032470Recruiting
Deep brain stimulation registry for essential tremor patients
This study collects information from adults with essential tremor who are getting deep brain stimulation under the hospital’s standard safety guidelines. It may help improve how this treatment is chosen and used for people with tremor over time.
InnsbruckAges 18 years+ - NCT04033497Recruiting
MRI study to tell tumor from dead tissue after brain radiation
This study uses MRI scans to figure out whether an enlarging spot in the brain after stereotactic (focused) radiation is still living tumor or dead tissue. It may help doctors better understand what’s happening after radiation and guide next treatment decisions.
Boston, MassachusettsAges 18 years+ - NCT04038502RecruitingPhase 2
Testing carboplatin or olaparib for gene-linked prostate cancer
This Phase 2 study tests whether carboplatin or olaparib can help people with prostate cancer that has certain DNA repair gene changes. It’s designed for advanced (metastatic) prostate cancer that is growing despite standard hormone-blocking treatment.
West Los Angeles, CaliforniaAges 18 years+ - NCT04043598Recruiting
Fluids choice after brain bleed to improve brain outcomes
This trial studies whether giving a specific type of IV fluid (a salt-water fluid in the vein) after a type of brain bleed can improve neurological recovery. It focuses on adults with a non-traumatic subarachnoid hemorrhage (a bleeding in the space around the brain) given soon after diagnosis.
Sankt Gallen, Canton of St. GallenAges 16 years+ - NCT04046237Recruiting
Treating gum disease to study heart artery inflammation after a heart attack
This study tests whether treating severe gum disease in people who recently had a heart attack can reduce inflammation in the artery plaque. It may help researchers understand if gum treatment could benefit heart health after a heart attack.
ParisAges 30–70 - NCT04045665RecruitingPhase 3
Blood thinner vs usual care for new heart rhythm after bypass surgery
This trial tests whether using a blood thinner in people with new, temporary atrial fibrillation after CABG (heart bypass surgery) can reduce harmful outcomes compared with standard treatment. It may help prevent stroke or other complications if your rhythm problem fits the trial’s timing and risk profile.
Little Rock, ArkansasAges 18 years+ - NCT04046523Recruiting
Test non-contact eye videos to measure brain pressure waves
This study uses a special video exam of your eyes to record patterns that may relate to brain pressure changes. It may help researchers find a safer, non-contact way to monitor pressure inside the skull.
Minneapolis, MinnesotaAges 4 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,422 recruiting neurology studies from the U.S. registry right now, out of 19,431 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.